| Entry |
|
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| Name |
Norfloxacin nicotinate;
Quinabic soluble powder (TN) [veterinary] |
|---|
| Formula |
C16H18FN3O3. C6H5NO2
|
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| Exact mass |
442.1652
|
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| Mol weight |
442.44
|
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| Structure |
|
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| Class |
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
Metabolizing enzyme substrate
DG01892 CYP1A2 substrate
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG02852 CYP3A/CYP3A4 inhibitor
|
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| Remark |
| Product (DG00620): | D00210<JP> |
|
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| Efficacy |
Antibacterial, Nucleic acid biosynthesis inhibitor |
|---|
| Target |
|
|---|
| Metabolism |
Enzyme: CYP1A2 [HSA: 1544]
|
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| Interaction |
|
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MA Fluoroquinolones
J01MA06 Norfloxacin
D08287 Norfloxacin nicotinate
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AE Fluoroquinolones
S01AE02 Norfloxacin
D08287 Norfloxacin nicotinate
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00620 Norfloxacin
D08287 Norfloxacin nicotinate
Metabolizing enzyme substrate
DG01892 CYP1A2 substrate
DG00620 Norfloxacin
D08287 Norfloxacin nicotinate
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00620 Norfloxacin
D08287 Norfloxacin nicotinate
DG02852 CYP3A/CYP3A4 inhibitor
DG00620 Norfloxacin
D08287 Norfloxacin nicotinate
Antimicrobials [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
D08287 Norfloxacin nicotinate
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08287
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00620 Norfloxacin
Metabolizing enzyme substrate
DG01892 CYP1A2 substrate
DG00620 Norfloxacin
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00620 Norfloxacin
DG02852 CYP3A/CYP3A4 inhibitor
DG00620 Norfloxacin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
DG00620 Norfloxacin
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 32
1 C8y C 24.7100 -18.2700
2 C8y C 24.7100 -16.8700
3 N4y N 25.9700 -18.9700
4 C8x C 23.5200 -18.9700
5 C8y C 25.9700 -16.1700
6 C8x C 23.5200 -16.1700
7 C8x C 27.1600 -18.2700
8 C1b C 25.9700 -20.3700
9 C8y C 22.2600 -18.2700
10 C8y C 27.1600 -16.8700
11 O5x O 25.9700 -14.7700
12 C8y C 22.2600 -16.8700
13 C1a C 24.7100 -21.0700
14 N1y N 21.0700 -18.9700
15 C6a C 28.4200 -16.1700
16 X F 21.0700 -16.2400
17 C1x C 19.8800 -18.2700
18 C1x C 21.0700 -20.3700
19 O6a O 29.6100 -16.8700
20 O6a O 28.4200 -14.7700
21 C1x C 18.6900 -18.9700
22 C1x C 19.8800 -21.0700
23 N1x N 18.6900 -20.3700
24 C8x C 32.6200 -17.2900
25 C8x C 32.6200 -18.6900
26 N5x N 33.8324 -19.3900
27 C8x C 35.0449 -18.6900
28 C8y C 35.0449 -17.2900
29 C8x C 33.8324 -16.5900
30 C6a C 36.2760 -16.5790
31 O6a O 37.4812 -17.2747
32 O6a O 36.2757 -15.1901
BOND 34
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 2
9 5 10 1
10 5 11 2
11 6 12 2
12 8 13 1
13 9 14 1
14 10 15 1
15 12 16 1
16 14 17 1
17 14 18 1
18 15 19 1
19 15 20 2
20 17 21 1
21 18 22 1
22 21 23 1
23 7 10 2
24 9 12 1
25 22 23 1
26 24 25 2
27 25 26 1
28 26 27 2
29 27 28 1
30 28 29 2
31 24 29 1
32 28 30 1
33 30 31 1
34 30 32 2
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