| Entry |
|
|---|
| Name |
Opipramol (INN);
Opipramol dura (TN) |
|---|
| Formula |
C23H29N3O
|
|---|
| Exact mass |
363.2311
|
|---|
| Mol weight |
363.50
|
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| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG01728 Tricyclic antidepressant
DG01560 Sigma receptor agonist
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidepressant |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AA Non-selective monoamine reuptake inhibitors
N06AA05 Opipramol
D08297 Opipramol (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00930 Opipramol
D08297 Opipramol
DG01728 Tricyclic antidepressant
DG00930 Opipramol
D08297 Opipramol
DG01560 Sigma receptor agonist
DG00930 Opipramol
D08297 Opipramol
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00930 Opipramol
D08297 Opipramol
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00930 Opipramol
D08297 Opipramol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D08297 Opipramol (INN)
Histamine
HRH1
D08297 Opipramol (INN)
Serotonin
HTR2
D08297 Opipramol (INN)
Transporters
Other transporters
Auxiliary transport proteins (TC:8.A)
SIGMAR1
D08297 Opipramol (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00930 Opipramol
DG01728 Tricyclic antidepressant
DG00930 Opipramol
DG01560 Sigma receptor agonist
DG00930 Opipramol
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00930 Opipramol
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00930 Opipramol
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 27
1 C2x C 20.4400 -21.5600
2 C8y C 19.6000 -20.4400
3 C8y C 19.8800 -19.0400
4 N1y N 21.1400 -18.4800
5 C2x C 21.8400 -21.5600
6 C8y C 22.4000 -19.1100
7 C8y C 22.7500 -20.5100
8 C8x C 18.9000 -18.0600
9 C8x C 17.5700 -18.4800
10 C8x C 17.2200 -19.8100
11 C8x C 18.2000 -20.7900
12 C8x C 24.0800 -20.9300
13 C8x C 25.1300 -19.9500
14 C8x C 24.7800 -18.6200
15 C8x C 23.4500 -18.2000
16 C1b C 21.1400 -17.0800
17 C1b C 22.3300 -16.4500
18 C1b C 23.5200 -17.1500
19 N1y N 24.7800 -16.4500
20 C1x C 25.9700 -17.1500
21 C1x C 27.2300 -16.5200
22 N1y N 27.2300 -15.1200
23 C1x C 25.9700 -14.3500
24 C1x C 24.7800 -15.0500
25 C1b C 28.4200 -14.4200
26 C1b C 29.6100 -15.1200
27 O1a O 30.8700 -14.4200
BOND 30
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 19 24 1
28 22 25 1
29 25 26 1
30 26 27 1
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