| Entry |
|
|---|
| Name |
Phenylephrine (INN);
Phenylephrine Minims (TN) |
|---|
| Formula |
C9H13NO2
|
|---|
| Exact mass |
167.0946
|
|---|
| Mol weight |
167.20
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
|
|---|
| Remark |
| Product (DG00215): | D00511<JP/US> |
| Product (mixture): | D10837<US> D11853<US> |
|
|---|
| Efficacy |
Vasoconstrictor, alpha1-Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07215 | alpha-Adrenergic receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA06 Phenylephrine
D08365 Phenylephrine (INN)
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AX Other agents for treatment of hemorrhoids and anal fissures for topical use
C05AX06 Phenylephrine
D08365 Phenylephrine (INN)
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AA Sympathomimetics, plain
R01AA04 Phenylephrine
D08365 Phenylephrine (INN)
R01AB Sympathomimetics, combinations excl. corticosteroids
R01AB01 Phenylephrine
D08365 Phenylephrine (INN)
R01B NASAL DECONGESTANTS FOR SYSTEMIC USE
R01BA Sympathomimetics
R01BA03 Phenylephrine
D08365 Phenylephrine (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01F MYDRIATICS AND CYCLOPLEGICS
S01FB Sympathomimetics excl. antiglaucoma preparations
S01FB01 Phenylephrine
D08365 Phenylephrine (INN)
S01G DECONGESTANTS AND ANTIALLERGICS
S01GA Sympathomimetics used as decongestants
S01GA05 Phenylephrine
D08365 Phenylephrine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Phenylephrine
D08365 Phenylephrine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00215 Phenylephrine
D08365 Phenylephrine
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG00215 Phenylephrine
D08365 Phenylephrine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D08365 Phenylephrine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00215 Phenylephrine
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
DG00215 Phenylephrine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 12
1 C8y C 13.1600 -38.5700
2 C8x C 13.1600 -39.9700
3 C8x C 14.3724 -40.6700
4 C8x C 15.5849 -39.9700
5 C8y C 15.5849 -38.5700
6 C8x C 14.3724 -37.8700
7 O1a O 11.9476 -37.8700
8 C1c C 16.8160 -37.8590
9 C1b C 18.0212 -38.5547
10 O1a O 16.8157 -36.4701
11 N1b N 19.2035 -37.8719
12 C1a C 20.3975 -38.5612
BOND 12
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 5 8 1
9 8 9 1
10 8 10 1 #Up
11 9 11 1
12 11 12 1
|
|---|
