| Entry |
|
|---|
| Name |
Pipotiazine (INN);
Piportil (TN) |
|---|
| Formula |
C24H33N3O3S2
|
|---|
| Exact mass |
475.1963
|
|---|
| Mol weight |
475.67
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
|
|---|
| Remark |
|
|---|
| Efficacy |
Antipsychotic, Neuroleptic |
|---|
| Comment |
Phenothiazine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AC Phenothiazines with piperidine structure
N05AC04 Pipotiazine
D08385 Pipotiazine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00884 Pipotiazine
D08385 Pipotiazine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD1
D08385 Pipotiazine (INN)
DRD2
D08385 Pipotiazine (INN)
Serotonin
HTR1A
D08385 Pipotiazine (INN)
HTR2A
D08385 Pipotiazine (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00884 Pipotiazine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 C8x C 14.2800 -22.4700
2 C8x C 15.4700 -21.7700
3 C8y C 15.4700 -20.3700
4 C8x C 14.2800 -19.6700
5 C8y C 13.0900 -21.7700
6 C8y C 13.0900 -20.3700
7 N1y N 11.9000 -19.6700
8 S2x S 11.9000 -22.4700
9 C8y C 10.7100 -21.7700
10 C8y C 10.7100 -20.3700
11 C8x C 9.4500 -19.6700
12 C8x C 8.2600 -20.3700
13 C8x C 8.2600 -21.7700
14 C8x C 9.4500 -22.4700
15 C1b C 11.9000 -18.2700
16 C1b C 13.0900 -17.5700
17 C1b C 13.0900 -16.2400
18 N1y N 14.2800 -15.5400
19 C1x C 15.4700 -16.1700
20 C1x C 16.6600 -15.5400
21 C1y C 16.6600 -14.1400
22 C1x C 15.4700 -13.4400
23 C1x C 14.2800 -14.1400
24 C1b C 17.8500 -13.4400
25 C1b C 19.1100 -14.1400
26 O1a O 20.3000 -13.4400
27 S4a S 16.7300 -19.6700
28 N1c N 17.9200 -20.3700
29 C1a C 19.1100 -19.6700
30 C1a C 17.9200 -21.7700
31 O3c O 17.7100 -18.6900
32 O3c O 15.6800 -18.6900
BOND 35
1 23 18 1
2 1 2 2
3 21 24 1
4 2 3 1
5 24 25 1
6 9 10 2
7 25 26 1
8 10 11 1
9 11 12 2
10 12 13 1
11 13 14 2
12 14 9 1
13 3 27 1
14 5 6 2
15 27 28 1
16 7 15 1
17 28 29 1
18 6 7 1
19 28 30 1
20 15 16 1
21 27 31 2
22 7 10 1
23 27 32 2
24 16 17 1
25 9 8 1
26 17 18 1
27 8 5 1
28 3 4 2
29 4 6 1
30 5 1 1
31 18 19 1
32 19 20 1
33 20 21 1
34 21 22 1
35 22 23 1
|
|---|
