KEGG   DRUG: Piroheptine
Entry
D08395                      Drug                                   
Name
Piroheptine (INN)
Formula
C22H25N
Exact mass
303.1987
Mol weight
303.44
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
  DG01745  Anticholinergic antiparkinson agent
 DG01967  Antiparkinson agent
Remark
Chemical structure group: DG01272
Product (DG01272): D01231<JP>
Efficacy
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
Target
CHRM [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Structure map
map07057  Antiparkinsonian agents
Brite
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01745  Anticholinergic antiparkinson agent
    DG01272  Piroheptine
     D08395  Piroheptine
  DG01967  Antiparkinson agent
   DG01272  Piroheptine
    D08395  Piroheptine
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D08395  Piroheptine (INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01745  Anticholinergic antiparkinson agent
    DG01272  Piroheptine
  DG01967  Antiparkinson agent
   DG01272  Piroheptine
Other DBs
CAS: 16378-21-5
PubChem: 96025081
ChEBI: 135287
LigandBox: D08395
LinkDB
KCF data

ATOM        23
            1   C1x C    23.4500  -21.8400
            2   C8y C    22.6100  -20.7200
            3   C8y C    22.8900  -19.3900
            4   C2y C    24.1500  -18.8300
            5   C1x C    24.8500  -21.8400
            6   C8y C    25.4100  -19.3900
            7   C8y C    25.6900  -20.7900
            8   C8x C    21.9100  -18.4100
            9   C8x C    20.5800  -18.7600
            10  C8x C    20.2300  -20.1600
            11  C8x C    21.2100  -21.1400
            12  C8x C    27.0200  -21.2100
            13  C8x C    28.0700  -20.3000
            14  C8x C    27.7900  -18.9000
            15  C8x C    26.4600  -18.4800
            16  C2y C    24.1500  -17.4300
            17  C1y C    25.2700  -16.5200
            18  N1y N    24.7800  -15.1900
            19  C1x C    23.3100  -15.2600
            20  C1x C    22.9600  -16.6600
            21  C1a C    26.6000  -16.9400
            22  C1b C    25.4100  -14.0000
            23  C1a C    26.8100  -14.0000
BOND        26
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    4  16 2
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   16  20 1
            24   17  21 1
            25   18  22 1
            26   22  23 1

» Japanese version   » Back

DBGET integrated database retrieval system