KEGG   DRUG: RilmenidineHelp
Entry
D08482                      Drug                                   

Name
Rilmenidine (INN);
Hyperium (TN)
Formula
C10H16N2O
Exact mass
180.1263
Mol weight
180.2468
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01738  Centrally-acting antiadrenergic
Remark
Same as: C11120
ATC code: C02AC06
Efficacy
Antihypertensive, alpha2-Adrenergic receptor agonist
Target
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING
    C02AC Imidazoline receptor agonists
     C02AC06 Rilmenidine
      D08482  Rilmenidine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA2
     D08482  Rilmenidine (INN)
BRITE hierarchy
Other DBs
CAS: 54187-04-1
PubChem: 96025168
ChEBI: 8862
ChEMBL: CHEMBL289480
LigandBox: D08482
NIKKAJI: J23.709D
LinkDB All DBs
KCF data Show

ATOM        13
            1   C1y C    24.0800  -15.6800
            2   C1x C    24.7100  -14.4900
            3   C1x C    23.3100  -14.4900
            4   C1x C    23.5200  -21.3500
            5   N2x N    24.0100  -20.0200
            6   C2y C    22.8200  -19.1800
            7   O2x O    21.7000  -20.0200
            8   C1x C    22.1200  -21.3500
            9   N1b N    22.8200  -17.7800
            10  C1c C    24.0800  -17.0800
            11  C1y C    25.2700  -17.7800
            12  C1x C    25.9700  -18.9700
            13  C1x C    26.6700  -17.7800
BOND        15
            1     5   6 2
            2     6   7 1
            3     7   8 1
            4     8   4 1
            5     1   2 1
            6     6   9 1
            7     1   3 1
            8     9  10 1
            9    10   1 1
            10    3   2 1
            11    4   5 1
            12   11  12 1
            13   11  13 1
            14   13  12 1
            15   10  11 1

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