KEGG   DRUG: Tropatepine hydrochloride
Entry
D08653                      Drug                                   

Name
Tropatepine hydrochloride;
Lepticur (TN)
Formula
C22H23NS. HCl
Exact mass
369.1318
Mol weight
369.9507
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
  DG01745  Anticholinergic antiparkinson agent
 DG01745  Anticholinergic antiparkinson agent
 DG01967  Antiparkinson agent
  DG01745  Anticholinergic antiparkinson agent
Remark
ATC code: N04AA12
Chemical structure group: DG00858
Efficacy
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
Comment
Atropine [CPD:C01479] derivative; Tricyclic compound
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA12 Tropatepine
      D08653  Tropatepine hydrochloride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D08653  Tropatepine hydrochloride
Other DBs
CAS: 27574-25-0
PubChem: 96025336
LigandBox: D08653
NIKKAJI: J262.605E
LinkDB
KCF data

ATOM        25
            1   X   Cl   27.4851  -17.6694
            2   C1x C    17.2176  -14.7680
            3   C1x C    17.4976  -13.6482
            4   C1y C    18.3374  -14.3481
            5   C1y C    18.6874  -13.2282
            6   N1y N    17.5676  -11.8984
            7   C1x C    20.0872  -14.3481
            8   C1x C    19.8772  -13.2282
            9   C2y C    21.0671  -14.9080
            10  C1a C    16.8676  -10.7086
            11  C2y C    21.0671  -16.3778
            12  C8y C    22.2569  -16.9377
            13  C8y C    22.5369  -18.1976
            14  S2x S    21.6970  -19.2474
            15  C8y C    19.8773  -16.9377
            16  C1x C    20.4372  -19.2474
            17  C8y C    19.5973  -18.1976
            18  C8x C    18.9674  -16.0279
            19  C8x C    17.7075  -16.3778
            20  C8x C    17.3576  -17.7076
            21  C8x C    18.3375  -18.5475
            22  C8x C    23.7967  -18.6175
            23  C8x C    24.7766  -17.7776
            24  C8x C    24.4966  -16.4478
            25  C8x C    23.2368  -16.0978
BOND        28
            1     2   3 1
            2     2   4 1
            3     3   5 1
            4     4   6 1
            5     4   7 1
            6     5   8 1
            7     7   9 1
            8     5   6 1
            9     8   9 1
            10    6  10 1
            11   13  14 1
            12   11  15 1
            13   14  16 1
            14   12  13 1
            15   15  17 1
            16   11  12 1
            17   16  17 1
            18   15  18 2
            19   18  19 1
            20   19  20 2
            21   20  21 1
            22   17  21 2
            23   13  22 2
            24   22  23 1
            25   23  24 2
            26   24  25 1
            27   12  25 2
            28    9  11 2

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