| Entry |
|
|---|
| Name |
Brivaracetam (JAN/USAN/INN);
Briviact (TN) |
|---|
| Product |
|
|---|
| Formula |
C11H20N2O2
|
|---|
| Exact mass |
212.1525
|
|---|
| Mol weight |
212.2887
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG03199 Antiepileptic agent
DG02038 Piracetam antiepileptic
Metabolizing enzyme substrate
DG01639 CYP2C19 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Anticonvulsant, Pain relief |
|---|
| Comment |
Levetiracetam [DR: D00709] derivative
Treatment of epilepsy, neuropathic pain and essential tremor
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP2C19 [HSA: 1557]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N03 ANTIEPILEPTICS
N03A ANTIEPILEPTICS
N03AX Other antiepileptics
N03AX23 Brivaracetam
D08879 Brivaracetam (JAN/USAN/INN) <US>
USP drug classification [BR:br08302]
Anticonvulsants
Anticonvulsants, Other
Potassium Channel Opener
Brivaracetam
D08879 Brivaracetam (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
Transporters
Major facilitator superfamily
VNT family
SV2A
D08879 Brivaracetam (JAN/USAN/INN) <US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D08879
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D08879
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D08879
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08879
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D08879
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 15
1 N1y N 29.4350 -21.8855
2 C1c C 30.6233 -21.1865
3 C5x C 28.2467 -21.0467
4 C1x C 28.9457 -23.2136
5 C5a C 31.8117 -21.8855
6 C1x C 27.1283 -21.8855
7 O5x O 28.2467 -19.6487
8 C1y C 27.5477 -23.2136
9 N1a N 33.0000 -21.1865
10 O5a O 31.8117 -23.2835
11 C1b C 26.7213 -24.3412
12 C1b C 25.3184 -24.1880
13 C1a C 24.4873 -25.3220
14 C1b C 30.6233 -19.7885
15 C1a C 31.8340 -19.0895
BOND 15
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 1
6 3 7 2
7 4 8 1
8 5 9 1
9 5 10 2
10 6 8 1
11 8 11 1 #Down
12 11 12 1
13 12 13 1
14 2 14 1 #Up
15 14 15 1
|
|---|
