KEGG   DRUG: BrivaracetamHelp
Entry
D08879                      Drug                                   

Name
Brivaracetam (USAN/INN);
Briviact (TN)
Product
Formula
C11H20N2O2
Exact mass
212.1525
Mol weight
212.2887
Structure
Mol fileKCF fileDB search
Class
Neuropsychiatric agent
 DG02038  Piracetam antiepileptics
Enzyme substrate
 DG01639  CYP2C19 substrate
Remark
ATC code: N03AX23
Product: D08879<US>
Efficacy
Anticonvulsant, Pain relief
Comment
Levetiracetam [DR:D00709] derivative
Treatment of epilepsy, neuropathic pain and essential tremor
Target
SV2A [HSA:9900] [KO:K06258]
  Pathway
hsa04512  ECM-receptor interaction
Metabolism
Enzyme: CYP2C19 [HSA:1557]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AX Other antiepileptics
     N03AX23 Brivaracetam
      D08879  Brivaracetam (USAN/INN) <US>
USP drug classification [BR:br08302]
 Anticonvulsants
  Anticonvulsants, Other
   Brivaracetam
    D08879  Brivaracetam (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Major facilitator superfamily
   VNT family
    SV2A
     D08879  Brivaracetam (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D08879
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D08879
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D08879
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and germline mutations
  D08879
BRITE hierarchy
Other DBs
CAS: 357336-20-0
PubChem: 96025562
ChEBI: 133013
ChEMBL: CHEMBL607400
LigandBox: D08879
LinkDB All DBs
KCF data Show

ATOM        15
            1   N1y N    29.4350  -21.8855
            2   C1c C    30.6233  -21.1865
            3   C5x C    28.2467  -21.0467
            4   C1x C    28.9457  -23.2136
            5   C5a C    31.8117  -21.8855
            6   C1x C    27.1283  -21.8855
            7   O5x O    28.2467  -19.6487
            8   C1y C    27.5477  -23.2136
            9   N1a N    33.0000  -21.1865
            10  O5a O    31.8117  -23.2835
            11  C1b C    26.7213  -24.3412
            12  C1b C    25.3184  -24.1880
            13  C1a C    24.4873  -25.3220
            14  C1b C    30.6233  -19.7885
            15  C1a C    31.8340  -19.0895
BOND        15
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     4   8 1
            8     5   9 1
            9     5  10 2
            10    6   8 1
            11    8  11 1 #Down
            12   11  12 1
            13   12  13 1
            14    2  14 1 #Up
            15   14  15 1

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