| Entry |
|
|---|
| Name |
Talaglumetad hydrochloride (USAN) |
|---|
| Formula |
C11H16N2O5. HCl
|
|---|
| Exact mass |
292.0826
|
|---|
| Mol weight |
292.71
|
|---|
| Structure |
|
|---|
| Efficacy |
Antianxiety, Glutamate metabotropic receptor agonist |
|---|
| Comment |
Treatment of anxiety and stress disorders (metabotropic glutamate (mGlu) agonist)
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Metabotropic glutamate receptor family
Glutamate (metabotropic)
GRM2
D09008 Talaglumetad hydrochloride (USAN)
GRM3
D09008 Talaglumetad hydrochloride (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
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|---|
| KCF data |
ATOM 19
1 C1y C 23.0668 -17.7924
2 C1y C 23.0668 -19.1869
3 C1z C 24.3916 -19.6750
4 C1x C 25.2283 -18.4897
5 C1x C 24.3916 -17.3740
6 C1y C 21.8117 -18.4897
7 C6a C 20.4869 -18.4897
8 O6a O 19.7896 -17.3043
9 O6a O 19.7896 -19.7447
10 C6a C 25.5770 -20.3723
11 N1b N 24.3916 -21.0696
12 O6a O 26.7623 -19.6750
13 O6a O 25.5770 -21.7668
14 C5a C 23.1839 -21.7668
15 C1c C 23.1839 -23.1614
16 C1a C 21.9931 -23.8491
17 O5a O 21.9931 -21.0791
18 N1a N 24.4082 -23.8684
19 X Cl 30.3184 -20.2328
BOND 19
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 1 6 1
7 2 6 1
8 6 7 1 #Up
9 7 8 1
10 7 9 2
11 3 10 1 #Up
12 3 11 1 #Down
13 10 12 1
14 10 13 2
15 11 14 1
16 14 15 1
17 15 16 1
18 14 17 2
19 15 18 1 #Up
|
|---|
