KEGG   DRUG: Ofatumumab
Entry
D09314                      Drug                                   
Name
Ofatumumab (USAN/INN);
Ofatumumab (genetical recombination) (JAN);
Arzerra (TN);
Kesimpta (TN)
Product
Formula
C6480H10022N1742O2020S44
Exact mass
145970.276
Mol weight
146060.2301
Remark
Therapeutic category: 1190
ATC code: L01FA02 L04AG12
Product: D09314<JP/US>
Efficacy
Antineoplastic, Anti-CD20 antibody
  Disease
Chronic lymphocytic leukemia [DS:H00005]
Multiple sclerosis [DS:H01490]
  Type
Monoclonal antibody
Target
CD20 [HSA:931] [KO:K06466]
  Pathway
hsa04640  Hematopoietic cell lineage
Interaction
Structure map
map07050  Antirheumatics - DMARDs and biological agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01F MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES
    L01FA CD20 (Clusters of Differentiation 20) inhibitors
     L01FA02 Ofatumumab
      D09314  Ofatumumab (USAN/INN) <JP/US>
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AG Monoclonal antibodies
     L04AG12 Ofatumumab
      D09314  Ofatumumab (USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Antineoplastics
  Monoclonal Antibody/Antibody-Drug Conjugate
   Ofatumumab
    D09314  Ofatumumab (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   119  Miscellaneous
    1190  Miscellaneous
     D09314  Ofatumumab (USAN/INN); Ofatumumab (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Other cell surface molecules
   CD molecules
    CD20
     D09314  Ofatumumab (USAN/INN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D09314
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D09314
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D09314
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09314
Pharmacogenomic biomarkers [br08341.html]
 Somatic variations in targeted cancer therapies
  D09314
Other DBs
CAS: 679818-59-8
PubChem: 96025994
LinkDB

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