| Entry |
|
|---|
| Name |
Talarozole (USAN/INN);
Rambazole (TN) |
|---|
| Formula |
C21H23N5S
|
|---|
| Exact mass |
377.1674
|
|---|
| Mol weight |
377.51
|
|---|
| Structure |
|
|---|
| Efficacy |
Anti-acne, Antipsoriatic |
|---|
| Comment |
Treatment of keratinization disorders, acne and psoriasis
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Cytochrome P450
CYP26
D09385 Talarozole (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 27
1 C8x C 22.6800 -24.8500
2 C8y C 22.6800 -26.2500
3 C8x C 23.8924 -26.9500
4 C8x C 25.1049 -26.2500
5 C8y C 25.1049 -24.8500
6 C8x C 23.8924 -24.1500
7 C1c C 26.3360 -24.1390
8 C1c C 27.5412 -24.8347
9 C1b C 28.7235 -24.1519
10 C1a C 29.9175 -24.8412
11 C1b C 27.5416 -26.2496
12 C1a C 28.7305 -26.9359
13 N4y N 26.3357 -22.7501
14 C8x C 27.4579 -21.9344
15 N5x N 27.0288 -20.6151
16 C8x C 25.6415 -20.6154
17 N5x N 25.2132 -21.9349
18 N1b N 21.4676 -26.9500
19 C8y C 20.2721 -26.2596
20 S2x S 20.1251 -24.8610
21 C8y C 18.7495 -24.5685
22 C8y C 18.0463 -25.7864
23 N5x N 18.9873 -26.8316
24 C8x C 18.0495 -23.3561
25 C8x C 16.6495 -23.3560
26 C8x C 15.9463 -24.5739
27 C8x C 16.6463 -25.7864
BOND 30
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 8 11 1
12 11 12 1
13 7 13 1
14 13 14 1
15 14 15 2
16 15 16 1
17 16 17 2
18 13 17 1
19 2 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 21 22 2
24 22 23 1
25 19 23 2
26 21 24 1
27 24 25 2
28 25 26 1
29 26 27 2
30 22 27 1
|
|---|
