| Entry |
|
|---|
| Name |
Varlitinib (USAN/INN) |
|---|
| Formula |
C22H19ClN6O2S
|
|---|
| Exact mass |
466.0979
|
|---|
| Mol weight |
466.94
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Receptor tyrosine kinase inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG01357 Varlitinib
D09689 Varlitinib
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
EGFR family
EGFR
D09689 Varlitinib (USAN/INN)
ERBB2 (HER2, CD340)
D09689 Varlitinib (USAN/INN)
ERBB4 (HER4)
D09689 Varlitinib (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG01357 Varlitinib
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 C8x C 27.3700 -18.8300
2 C8y C 27.3700 -20.2300
3 C8x C 26.1800 -20.9300
4 C8y C 24.9200 -20.2300
5 C8y C 24.9200 -18.8300
6 C8x C 26.1800 -18.1300
7 C8y C 23.7300 -20.9300
8 N5x N 22.5400 -20.2300
9 C8x C 22.5400 -18.8300
10 N5x N 23.7300 -18.1300
11 N1b N 23.7300 -22.3300
12 N1b N 28.5600 -20.9300
13 C2y C 29.7500 -20.2300
14 O2x O 29.7500 -18.8300
15 C1x C 31.0800 -18.4100
16 C1y C 31.9200 -19.5300
17 N2x N 31.0800 -20.6500
18 C1a C 33.3200 -19.5300
19 C8y C 24.9453 -23.0251
20 C8x C 24.9511 -24.4297
21 C8y C 26.1664 -25.1247
22 C8y C 27.3759 -24.4197
23 C8x C 27.3701 -23.0151
24 C8x C 26.1548 -22.3201
25 X Cl 26.1721 -26.5300
26 O2a O 28.5912 -25.1146
27 C1b C 29.7707 -24.4271
28 C8y C 30.9716 -25.1139
29 S2x S 30.9562 -26.5299
30 C8x C 32.2939 -26.9825
31 C8x C 33.1378 -25.8501
32 N5x N 32.3216 -24.6977
BOND 36
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 5 10 1
12 7 11 1
13 2 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 13 17 2
20 16 18 1 #Up
21 11 19 1
22 19 20 2
23 20 21 1
24 21 22 2
25 22 23 1
26 23 24 2
27 19 24 1
28 21 25 1
29 22 26 1
30 26 27 1
31 27 28 1
32 28 29 1
33 29 30 1
34 30 31 2
35 31 32 1
36 28 32 2
|
|---|
