Entry |
|
Name |
Edivoxetine (USAN/INN) |
Formula |
C18H26FNO4
|
Exact mass |
339.1846
|
Mol weight |
339.40
|
Structure |
|
Simcomp |
|
Class |
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
|
Remark |
|
Efficacy |
Antidepressant, Selective noradrenaline reuptake inhibitor (NRI) |
Comment |
Treatment of depression and attention deficit disorder
|
Target |
|
Interaction |
|
Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG01310 Edivoxetine
D09890 Edivoxetine
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D09890 Edivoxetine (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG01310 Edivoxetine
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 24
1 C8x C 20.8600 -20.7900
2 C8x C 20.8600 -19.3900
3 C8y C 22.0500 -18.6900
4 C8y C 23.3100 -19.3900
5 C8x C 23.3100 -20.7900
6 C8y C 22.0500 -21.4900
7 C1b C 24.5000 -18.6900
8 C1d C 25.6900 -19.3900
9 C1y C 25.6900 -20.7900
10 C1x C 24.5000 -21.4900
11 C1x C 26.9500 -21.4900
12 C1x C 26.9500 -22.8900
13 O2x O 25.6900 -23.5900
14 C1x C 24.5000 -22.8900
15 O2a O 22.0500 -17.2900
16 X F 22.0500 -22.8900
17 C1a C 23.3100 -16.5900
18 C1y C 26.9500 -18.6900
19 O2x O 26.9500 -17.2900
20 C1x C 28.1400 -16.5900
21 C1x C 29.3300 -17.2900
22 N1x N 29.3300 -18.6900
23 C1x C 28.1400 -19.3900
24 O1a O 26.9500 -20.0900
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 9 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 10 14 1
16 3 15 1
17 6 16 1
18 15 17 1
19 8 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 21 22 1
24 22 23 1
25 18 23 1
26 8 24 1 #Up
|