Entry |
|
Name |
Plecanatide (USAN/INN); Trulance (TN) |
Product |
|
Formula |
C65H104N18O26S4
|
Exact mass |
1680.6252
|
Mol weight |
1681.8863
|
Sequence |
Asn Asp Glu Cys Glu Leu Cys Val Asn Val Ala Cys Thr Gly Cys Leu (Disulfide bridge: 4-12, 7-15) |
Type |
Peptide |
Remark |
|
Efficacy |
Peristaltic accelerator, Enterotoxin receptor agonist |
Disease |
Irritable bowel syndrome [DS: H01615] |
Comment |
synthetic analog of Uroguanylin [CPD: C16006]
Chronic constipation, irritable bowel syndrome with constipation
|
Target |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A06 DRUGS FOR CONSTIPATION
A06A DRUGS FOR CONSTIPATION
A06AX Other drugs for constipation
A06AX07 Plecanatide
D09948 Plecanatide (USAN/INN) <US>
USP drug classification [BR:br08302]
Gastrointestinal Agents
Anti-Constipation Agents
Plecanatide
D09948 Plecanatide (USAN/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Lyases (EC4)
Phosphorus-oxygen lyases
GUCY2C
D09948 Plecanatide (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D09948
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D09948
|
Other DBs |
|
LinkDB |
|