KEGG   DRUG: PlecanatideHelp
Entry
D09948                      Drug                                   

Name
Plecanatide (USAN/INN)
Product
Formula
C65H104N18O26S4
Exact mass
1680.6252
Mol weight
1681.8863
Remark
ATC code: A06AX07
Product: D09948<US>
Efficacy
Peristaltic accelerator, Enterotoxin receptor agonist
Comment
synthetic analog of Uroguanylin [CPD:C16006]
Chronic constipation, irritable bowel syndrome with constipation
Target
GUCY2C [HSA:2984] [KO:K12320]
  Pathway
hsa00230  Purine metabolism
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A06 DRUGS FOR CONSTIPATION
   A06A DRUGS FOR CONSTIPATION
    A06AX Other drugs for constipation
     A06AX07 Plecanatide
      D09948  Plecanatide (USAN/INN) <US>
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases (EC4)
   Phosphorus-oxygen lyases
    GUCY2C
     D09948  Plecanatide (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D09948
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09948
BRITE hierarchy
Other DBs
CAS: 467426-54-6
PubChem: 124490630
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