KEGG   DRUG: Vatreptacog alfa (activated) (genetica recombination)
Entry
D10139                      Drug                                   

Name
Vatreptacog alfa (activated) (genetica recombination) (JAN);
Vatreptacog alfa (activated) (INN)
Formula
C1981H3051N561O620S27
Exact mass
45482.6917
Mol weight
45511.5633
Sequence
ANAFLXXLRP GSLXRXCKXX QCSFXXARXI FKDAXRTKLF WISYSDGDQC ASSPCQNGGS
CKDQLQSYIC FCLPAFEGRN CETHKDDQLI CVNENGGCEQ YCSDHTGTKR SCRCHEGYSL
LADGVSCTPT VEYPCGKIPI LEKRNASKPQ GRIVGGKDCP KGECPWQVLL LVNGAQLCGG
TLINTIWVVS AAHCFDKIKN WRNLIAVLGE HDLSEHDGDE QSRRVAQVII PSTYVPGTTN
HDIALLRLHQ PVVLTDHVVP LCLPERTFSE RTLAFVRFSL VSGWGQLLDR GATALVLQVL
NVPRLMTQDC LQQSRKVGDS PNITEYMFCA GYSDGSKDSC KGDSGGPHAT HYRGTWYLTG
IVSWGQGCAT VGHFGVYTRV SQYIEWLQKL MRSEPRPGVL LRAPFP
(Disulfide bridge: 17-22, 50-61, 55-70, 72-81, 91-102, 98-112, 114-127, 135-262, 159-164, 178-194, 310-329, 340-368; Glycosylation site: 52S, 60S, 145N, 322N)
  Type
Peptide
Class
Cardiovascular agent
 DG02016  Hemostatics
  DG02013  Blood coagulation factor
  DG02014  Blood coagulation accelerant
   DG02013  Blood coagulation factor
Remark
ATC code: B02BD05
Chemical structure group: DG00172
Product (DG00172): D00172<JP/US>
Efficacy
Bleeding suppressant, Replenisher (coagulation factor)
Comment
human FVIIa [HSA:2155] [KO:K01320] analog
blood coagulation factor VII
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02B VITAMIN K AND OTHER HEMOSTATICS
    B02BD Blood coagulation factors
     B02BD05 Coagulation factor VII
      D10139  Vatreptacog alfa (activated) (genetica recombination) (JAN)
Other DBs
CAS: 897936-89-9
PubChem: 135626857
LinkDB

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