| Entry |
|
|---|
| Name |
Valaciclovir hydrochloride hydrate (JAN);
Valaciclovir (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C13H20N6O4. HCl. xH2O
|
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| Structure |
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| Simcomp |
|
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| Class |
Antiviral
DG02840 Anti-herpesvirus agent
|
|---|
| Remark |
| Therapeutic category: | 6250 |
| Product (DG00647): | D00398<JP/US> D10518<JP/US> |
|
|---|
| Efficacy |
Antiviral, DNA polymerase inhibitor |
|---|
| Comment |
Active form of prodrug: Aciclovir [DR: D00222]
|
|---|
| Target |
Herpesvirus DNA polymerase [KO: K18964] |
|---|
| Pathway |
|
|---|
| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
J05AB11 Valaciclovir
D10518 Valaciclovir hydrochloride hydrate (JAN) <JP/US>
USP drug classification [BR:br08302]
Antivirals
Antiherpetic Agents
Valacyclovir
D10518 Valaciclovir hydrochloride hydrate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
625 Antivirals
6250 Antivirals
D10518 Valaciclovir hydrochloride hydrate (JAN)
Drug groups [BR:br08330]
Antiviral
DG02840 Anti-herpesvirus agent
DG00647 Valaciclovir
D10518 Valaciclovir hydrochloride hydrate
Drug classes [BR:br08332]
Antiviral
DG02840 Anti-herpesvirus agent
D10518 Valaciclovir hydrochloride hydrate
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D10518 Valaciclovir hydrochloride hydrate (JAN) <JP/US>
Drug groups [BR:br08330]
Antiviral
DG02840 Anti-herpesvirus agent
DG00647 Valaciclovir
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
DG00647 Valaciclovir
Prodrugs [br08324.html]
DG00647
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 X Cl 30.1700 -16.1700
2 N4y N 22.0500 -17.0100
3 C8y C 23.3100 -16.5200
4 C8y C 23.3100 -15.1200
5 N5x N 21.9800 -14.7000
6 C8x C 21.2100 -15.8900
7 N5x N 24.5700 -17.2200
8 C8y C 25.7600 -16.5200
9 N4x N 25.7600 -15.1200
10 C8y C 24.5000 -14.3500
11 O5x O 24.5000 -12.9500
12 N1a N 27.0200 -17.1500
13 C1b C 22.0500 -18.4100
14 O2a O 20.7900 -19.1100
15 C1b C 19.6000 -18.4100
16 C1b C 18.4100 -19.1100
17 O7a O 17.2200 -18.4100
18 C7a C 15.9600 -19.0400
19 C1c C 14.7700 -18.4100
20 C1c C 13.5800 -19.0400
21 C1a C 12.3900 -18.3400
22 C1a C 13.5800 -20.5100
23 O6a O 15.9600 -20.5100
24 N1a N 14.7700 -17.0100
25 O0 O 30.1700 -19.9500
BOND 24
1 2 3 1
2 3 4 2
3 4 5 1
4 5 6 2
5 2 6 1
6 3 7 1
7 7 8 2
8 8 9 1
9 9 10 1
10 4 10 1
11 10 11 2
12 8 12 1
13 2 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 20 21 1
22 20 22 1
23 18 23 2
24 19 24 1 #Down
BRACKET 1 28.0000 -20.6500 28.0000 -18.7600
1 30.8700 -18.7600 30.8700 -20.6500
1 x
ORIGINAL 1 25
REPEAT 1
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