| Entry |
|
|---|
| Name |
Clindamycin phosphate hydrate (JAN) |
|---|
| Formula |
C18H34ClN2O8PS. H2O
|
|---|
| Exact mass |
522.1568
|
|---|
| Mol weight |
522.98
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01578 Lincosamide antibiotic
|
|---|
| Remark |
| Product (DG00435): | D00277<US> D01073<JP/US> D01990<US> D02132<JP/US> |
| Product (mixture): | D10602<JP/US> D11084<US> D12969<US> |
|
|---|
| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
|---|
| Comment |
Semisynthetic lincosamide
Active form of prodrug: Clindamycin [DR: D00277]
|
|---|
| Target |
50S ribosomal subunit |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D10 ANTI-ACNE PREPARATIONS
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AF Antiinfectives for treatment of acne
D10AF01 Clindamycin
D10531 Clindamycin phosphate hydrate (JAN)
G GENITO URINARY SYSTEM AND SEX HORMONES
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01AA Antibiotics
G01AA10 Clindamycin
D10531 Clindamycin phosphate hydrate (JAN)
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
J01FF Lincosamides
J01FF01 Clindamycin
D10531 Clindamycin phosphate hydrate (JAN)
Drug groups [BR:br08330]
Antibacterial
DG01578 Lincosamide antibiotic
DG00435 Clindamycin
D10531 Clindamycin phosphate hydrate
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Lincosamide
D10531 Clindamycin phosphate hydrate (JAN)
Drug groups [BR:br08330]
Antibacterial
DG01578 Lincosamide antibiotic
DG00435 Clindamycin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Lincosamide
DG00435 Clindamycin
Prodrugs [br08324.html]
DG00435
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 32
1 C1y C 22.7500 -16.2400
2 C1y C 22.7500 -17.6400
3 C1y C 23.9400 -18.3400
4 C1y C 25.1300 -17.6400
5 C1y C 25.1300 -16.2400
6 O2x O 23.9400 -15.5400
7 S2a S 26.3900 -15.5400
8 C1a C 26.3900 -14.1400
9 O2b O 26.3900 -18.3400
10 O1a O 23.9400 -19.7400
11 O1a O 21.4900 -18.3400
12 C1c C 21.4900 -15.5400
13 N1b N 20.3000 -16.2400
14 C1c C 21.4900 -14.1400
15 X Cl 20.3000 -13.4400
16 C1a C 22.7500 -13.4400
17 C5a C 19.1100 -15.5400
18 C1y C 17.8500 -16.2400
19 O5a O 19.1100 -14.1400
20 N1y N 16.7300 -15.4700
21 C1x C 15.6100 -16.2400
22 C1y C 16.1000 -17.5700
23 C1x C 17.4300 -17.5700
24 C1a C 16.7300 -14.0700
25 C1b C 15.4000 -18.8300
26 C1b C 14.0000 -18.8300
27 C1a C 13.3000 -20.0200
28 P1b P 27.5800 -17.6400
29 O1c O 28.7700 -16.9400
30 O1c O 26.8800 -16.3800
31 O1c O 28.2800 -18.8300
32 O0 O 33.2500 -18.7600
BOND 32
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 5 7 1 #Down
8 7 8 1
9 4 9 1 #Down
10 3 10 1 #Up
11 2 11 1 #Up
12 1 12 1
13 12 13 1
14 12 14 1
15 14 15 1 #Up
16 14 16 1
17 13 17 1
18 18 17 1 #Down
19 17 19 2
20 18 20 1
21 20 21 1
22 21 22 1
23 22 23 1
24 18 23 1
25 20 24 1
26 22 25 1 #Up
27 25 26 1
28 26 27 1
29 9 28 1
30 28 29 1
31 28 30 2
32 28 31 1
|
|---|
