KEGG   DRUG: Umeclidinium bromide and vilanterolHelp
Entry
D10533            Mixture   Drug                                   

Name
Umeclidinium bromide and vilanterol;
Anoro (TN)
Product
Component
Umeclidinium bromide [DR:D10181], (Vilanterol trifenatate [DR:D09697] | Vilanterol [DR:D09696])
Remark
Therapeutic category: 2259
ATC code: R03AL03
Product: D10533<JP/US>
Efficacy
Bronchodilator
  Disease
Chronic obstructive pulmonary disease [DS:H01714]
Comment
Umeclidinium bromide is primarily metabolized by CYP2D6.
Vilanterol trifenatate is primarily metabolized by CYP3A4.
Metabolism
Enzyme: CYP2D6 [HSA:1565], CYP3A4 [HSA:1576]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03A ADRENERGICS, INHALANTS
    R03AL Adrenergics in combination with anticholinergics incl. triple combinations with corticosteroids
     R03AL03 Vilanterol and umeclidinium bromide
      D10533  Umeclidinium bromide and vilanterol <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  22  Respiratory organ agents
   225  Bronchodilators
    2259  Others
     D10533  Umeclidinium bromide and vilanterol
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D10533
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10533
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D10533
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10533
BRITE hierarchy
Other DBs
PubChem: 254741495
LinkDB All DBs

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