KEGG   DRUG: Nonacog beta pegolHelp
Entry
D10757                      Drug                                   

Name
Nonacog beta pegol (INN);
Nonacog beta pegol (genetical recombination) (JAN);
Refixia (TN)
Formula
C2041H3114N558O641S25
Exact mass
46496.1245
Mol weight
46525.5429
Sequence
YNSGKLXXFV QGNLXRXCMX XKCSFXXARX VFXNTXRTTX FWKQYVDGDQ CESNPCLNGG
SCKDDINSYE CWCPFGFEGK NCELDVTCNI KNGRCEQFCK NSADNKVVCS CTEGYRLAEN
QKSCEPAVPF PCGRVSVSQT SKLTRAEAVF PDVDYVNSTE AETILDNITQ STQSFNDFTR
VVGGEDAKPG QFPWQVVLNG KVDAFCGGSI VNEKWIVTAA HCVETGVKIT VVAGEHNIEE
TEHTEQKRNV IRIIPHHNYN AAINKYNHDI ALLELDEPLV LNSYVTPICI ADKEYTNIFL
KFGSGYVSGW GRVFHKGRSA LVLQYLRVPL VDRATCLRST KFTIYNNMFC AGFHEGGRDS
CQGDSGGPHV TEVEGTSFLT GIISWGEECA MKGKYGIYTK VSRYVNWIKE KTKLT
(Disulfide bridge: 18-23, 51-62, 56-71, 73-82, 88-99, 95-109, 111-124, 132-289, 206-222, 336-350, 361-389)
  Type
Peptide
Class
Cardiovascular agent
 DG02016  Hemostatics
  DG02013  Blood coagulation factor
  DG02014  Blood coagulation accelerant
   DG02013  Blood coagulation factor
Remark
Therapeutic category: 6343
ATC code: B02BD04
Chemical structure group: DG00171
Product (DG00171): D08797<JP/US> D08794<JP> D05201<JP> D10538<JP> D10757<JP> D10770<JP>
Efficacy
Bleeding suppressant, Replenisher (coagulation factor)
Comment
blood coagulation factor
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02B VITAMIN K AND OTHER HEMOSTATICS
    B02BD Blood coagulation factors
     B02BD04 Coagulation factor IX
      D10757  Nonacog beta pegol (INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   634  Human blood preparations
    6343  Plasma preparations
     D10757  Nonacog beta pegol (INN); Nonacog beta pegol (genetical recombination) (JAN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10757
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D10757
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10757
BRITE hierarchy
Other DBs
CAS: 1175512-71-6
PubChem: 295369347
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