| Entry |
|
|---|
| Name |
Polatuzumab vedotin (USAN);
Polatuzumab vedotin (genetical recombination) (JAN);
Polatuzumab vedotin-piiq;
Polivy (TN) |
|---|
| Product |
|
|---|
| Formula |
C6670H10317N1745O2087S40
|
|---|
| Exact mass |
149533.3646
|
|---|
| Mol weight |
149625.3253
|
|---|
| Class |
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
|
|---|
| Remark |
| Therapeutic category: | 4291 |
|
|---|
| Efficacy |
Antineoplastic |
|---|
| Disease |
Diffuse large B-cell lymphoma [DS: H02434] |
|---|
| Comment |
Antibody-drug conjugate
See Vedotin [DR: D09691]
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04662 | B cell receptor signaling pathway |
|
|---|
| Metabolism |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01X OTHER ANTINEOPLASTIC AGENTS
L01XC Monoclonal antibodies
L01XC37 Polatuzumab vedotin
D10761 Polatuzumab vedotin (USAN) <JP/US>
USP drug classification [BR:br08302]
Antineoplastics
Monoclonal Antibody/Antibody-Drug Conjugate
Polatuzumab Vedotin
D10761 Polatuzumab vedotin (USAN)
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
429 Miscellaneous
4291 Other Antitumors
D10761 Polatuzumab vedotin (USAN); Polatuzumab vedotin (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
Cell surface molecules and ligands
Other cell surface molecules
CD molecules
CD79B
D10761 Polatuzumab vedotin (USAN) <JP/US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D10761
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D10761
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D10761
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D10761
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D10761
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| Other DBs |
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| LinkDB |
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