KEGG   Homo sapiens (human): 974
Entry
974               CDS       T01001                                 
Symbol
CD79B, AGM6, B29, IGB, Igbeta
Name
(RefSeq) CD79b molecule
  KO
K06507  CD79B antigen
Organism
hsa  Homo sapiens (human)
Pathway
hsa04662  B cell receptor signaling pathway
Disease
H00085  Agammaglobulinemias
H02424  Primary central nervous system lymphoma
H02434  Diffuse large B-cell lymphoma, not otherwise specified
Drug target
Polatuzumab vedotin: D10761<JP/US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04662 B cell receptor signaling pathway
    974 (CD79B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    974 (CD79B)
CD molecules [BR:hsa04090]
 Proteins
  974 (CD79B)
SSDB
Motif
Pfam: V-set I-set Ig_3 ig ITAM Ig_6 Ig_2 Ig_4 Adeno_E3_CR1
Other DBs
NCBI-GeneID: 974
NCBI-ProteinID: NP_000617
OMIM: 147245
HGNC: 1699
Ensembl: ENSG00000007312
Pharos: P40259(Tbio)
UniProt: P40259
Structure
LinkDB
Position
17:complement(63928740..63932331)
AA seq 229 aa
MARLALSPVPSHWMVALLLLLSAEPVPAARSEDRYRNPKGSACSRIWQSPRFIARKRGFT
VKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNGIY
FCQQKCNNTSEVYQGCGTELRVMGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLL
LDKDDSKAGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE
NT seq 690 nt   +upstreamnt  +downstreamnt
atggccaggctggcgttgtctcctgtgcccagccactggatggtggcgttgctgctgctg
ctctcagctgagccagtaccagcagccagatcggaggaccggtaccggaatcccaaaggt
agtgcttgttcgcggatctggcagagcccacgtttcatagccaggaaacggggcttcacg
gtgaaaatgcactgctacatgaacagcgcctccggcaatgtgagctggctctggaagcag
gagatggacgagaatccccagcagctgaagctggaaaagggccgcatggaagagtcccag
aacgaatctctcgccaccctcaccatccaaggcatccggtttgaggacaatggcatctac
ttctgtcagcagaagtgcaacaacacctcggaggtctaccagggctgcggcacagagctg
cgagtcatgggattcagcaccttggcacagctgaagcagaggaacacgctgaaggatggt
atcatcatgatccagacgctgctgatcatcctcttcatcatcgtgcctatcttcctgctg
ctggacaaggatgacagcaaggctggcatggaggaagatcacacctacgagggcctggac
attgaccagacagccacctatgaggacatagtgacgctgcggacaggggaagtgaagtgg
tctgtaggtgagcacccaggccaggagtga

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