KEGG   DRUG: Sacituzumab govitecan
Entry
D10985                      Drug                                   
Name
Sacituzumab govitecan (USAN/INN);
Sacituzumab govitecan (genetical recombination) (JAN);
Sacituzumab govitecan-hziy;
Trodelvy (TN)
Product
Remark
ATC code: L01FX17
Product: D10985<US>
Efficacy
Antineoplastic, Topoisomerase I inhibitor
  Disease
Breast cancer (triple negative) [DS:H00031]
  Type
Antibody-drug conjugate
Target
TOP1 [HSA:7150] [KO:K03163]
TACSTD2 (TROP2) [HSA:4070] [KO:K17288]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01F MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES
    L01FX Other monoclonal antibodies and antibody drug conjugates
     L01FX17 Sacituzumab govitecan
      D10985  Sacituzumab govitecan (USAN/INN) <US>
USP drug classification [BR:br08302]
 Antineoplastics
  Monoclonal Antibody/Antibody-Drug Conjugate
   Sacituzumab Govitecan
    D10985  Sacituzumab govitecan (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Other cell surface molecules
   Other
    TACSTD2 (TROP2)
     D10985  Sacituzumab govitecan (USAN/INN) <US>
 Enzymes
  Isomerases (EC5)
   DNA topoisomerase
    TOP1
     D10985  Sacituzumab govitecan (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D10985
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10985
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10985
Pharmacogenomic biomarkers [br08341.html]
 Somatic variations in targeted cancer therapies
  D10985
 Polymorphisms and mutations affecting drug response
  D10985
Other DBs
CAS: 1491917-83-9
PubChem: 350078336
LinkDB

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