| Entry |
|
|---|
| Name |
Evocalcet (JAN/INN);
Orkedia (TN)
|
|---|
| Formula |
C24H26N2O2
|
|---|
| Exact mass |
374.1994
|
|---|
| Mol weight |
374.4754
|
|---|
| Structure |
   |
|---|
| Remark |
| Therapeutic category: | 3999 |
|
|---|
| Efficacy |
Antihyperparathyroidism, Calcium-sensing receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04621 | NOD-like receptor signaling pathway |
| hsa04928 | Parathyroid hormone synthesis, secretion and action |
|
|---|
| Interaction |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
399 Miscellaneous
3999 Others
D11063 Evocalcet (JAN/INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Metabotropic glutamate receptor family
Calcium-sensing
CASR
D11063 Evocalcet (JAN/INN) <JP>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D11063
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D11063
 |
|---|
| Other DBs |
|
|---|
| LinkDB |
 |
|---|
| KCF data |
ATOM 28
1 C8x C 11.9700 -14.4200
2 C8y C 11.9700 -15.8200
3 C8y C 13.2300 -16.5200
4 C8y C 14.4200 -15.8200
5 C8x C 14.4200 -14.4200
6 C8x C 13.2300 -13.7200
7 C8x C 10.7800 -16.5200
8 C8x C 10.7800 -17.9200
9 C8x C 11.9700 -18.6200
10 C8x C 13.2300 -17.9200
11 C1c C 15.6800 -16.5200
12 N1b N 16.8700 -15.8200
13 C1y C 18.0600 -16.5200
14 C1a C 15.6800 -17.9200
15 C1x C 19.1800 -15.6800
16 N1y N 20.3000 -16.5200
17 C1x C 19.8800 -17.8500
18 C1x C 18.4800 -17.8500
19 C8y C 21.4900 -15.8200
20 C8x C 21.4900 -14.4200
21 C8x C 22.7500 -13.7200
22 C8y C 23.9400 -14.4200
23 C8x C 23.9400 -15.8200
24 C8x C 22.7500 -16.5200
25 C1b C 25.1300 -13.7200
26 C6a C 26.3200 -14.4200
27 O6a O 27.5100 -13.7200
28 O6a O 26.3200 -15.8200
BOND 31
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 3 10 1
12 4 11 1
13 11 12 1
14 13 12 1 #Down
15 11 14 1 #Down
16 13 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 13 18 1
21 16 19 1
22 19 20 2
23 20 21 1
24 21 22 2
25 22 23 1
26 23 24 2
27 19 24 1
28 22 25 1
29 25 26 1
30 26 27 1
31 26 28 2
|
|---|
