KEGG ORTHOLOGY: K04612

ORTHOLOGY: K04612

Entry

K04612                      KO

Symbol

CASR

Name

calcium-sensing receptor

Pathway

map04621

NOD-like receptor signaling pathway

map04928

Parathyroid hormone synthesis, secretion and action

Disease

H00239

Bartter syndrome

H00245

Calcium sensing receptor (CASR) related disease

H00246

Primary hyperparathyroidism

H00808

Idiopathic generalized epilepsies

H01558

Parathyroid carcinoma

H02026

Familial hypocalciuric hypercalcemia

H02030

Neonatal hyperparathyroidism

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K04612  CASR; calcium-sensing receptor
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    K04612  CASR; calcium-sensing receptor
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04612  CASR; calcium-sensing receptor
G protein-coupled receptors [BR:ko04030]
Metabotropic glutamate receptor family
  Calcium-sensing
   K04612  CASR; calcium-sensing receptor

Other DBs

TC:	9.A.14.7.2

Genes

HSA:

846(CASR)

PTR:	460628(CASR)

PPS:	100982027(CASR)

GGO:	101140602(CASR)

PON:	100459602(CASR)

PPYG:

129034013(CASR)

NLE:	100602462(CASR)

HMH:	116466872(CASR)

SSYN:

129471090(CASR)

MCC:	714441(CASR)

MCF:	101867346(CASR)

MTHB:

126949203

MNI:	105470290(CASR)

CSAB:

103228191(CASR)

CATY:

105589770(CASR)

PANU:

101006482(CASR)

TGE:	112618778(CASR)

MLEU:

105533200(CASR)

RRO:	104667917(CASR)

RBB:	108541446(CASR)

TFN:	117083424(CASR)

PTEH:

111541991(CASR)

CANG:

105518007(CASR)

CJC:	100406413(CASR)

SBQ:	101044482(CASR)

CIMI:

108288946(CASR)

ANAN:

105733676(CASR)

CSYR:

103255016(CASR)

MMUR:

105879893(CASR)

LCAT:

123641988(CASR)

PCOQ:

105807262(CASR)

OGA:	100958607(CASR)

MMU:	12374(Casr)

MCAL:

110311755(Casr)

MPAH:

110329728(Casr)

RNO:	24247(Casr)

MCOC:

116085875(Casr)

ANU:	117702176 117717936(Casr)

ASYL:

127666184(Casr)

MUN:	110541014(Casr)

CGE:	100766791(Casr)

MAUA:

101837593(Casr)

PROB:

127227126(Casr)

PLEU:

114687677(Casr)

MORG:

121461942(Casr)

MFOT:

126488719

AAMP:

119825523(Casr)

NGI:	103741970(Casr)

HGL:	101725174(Casr)

CPOC:

100718111(Casr)

DORD:

105987931(Casr)

DSP:	122099610(Casr)

PLOP:

125351758(Casr)

NCAR:

124993205

MMMA:

107143540(Casr)

ITI:	101959624(Casr)

OCU:

100341543

OPI:	101528758(CASR)

TUP:	102477960(CASR)

GVR:	103606565(CASR)

CFA:	488007(CASR)

CLUD:

112677341(CASR)

VVP:	112913490(CASR)

VLG:	121485228(CASR)

NPO:	129503977(CASR)

AML:	100483630(CASR)

UMR:	103678767(CASR)

UAH:	113252194(CASR)

UAR:	123802092(CASR)

ELK:

111155111

LLV:

125103649

MPUF:

101686145(CASR)

MNP:	132011849(CASR)

MLK:	131824615(CASR)

NVS:	122908885(CASR)

ORO:	101385726(CASR)

EJU:	114214811(CASR)

ZCA:	113915935(CASR)

MLX:	118007038(CASR)

NSU:	110582450(CASR)

LWW:	102730587(CASR)

FCA:	100302732(CASR)

PYU:	121036317(CASR)

PCOO:

112849689(CASR)

PBG:	122491503(CASR)

PVIV:

125174628(CASR)

LRUF:

124526398

LGF:	123610957(CASR)

AJU:

106984104

PTG:	102954246(CASR)

PPAD:

109266471(CASR)

PUC:

125921008

PLEZ:

122198628(CASR)

HHV:	120237395(CASR)

BTA:	281038(CASR)

BOM:	102275412(CASR)

BIU:	109554157(CASR)

BBUB:

102407958(CASR)

BBIS:

104984500(CASR)

CHX:	102185783(CASR)

OAS:	101112527(CASR)

BTAX:

128055592(CASR)

CSUM:

138090926(CASR)

ODA:	120870967(CASR)

CCAD:

122444626(CASR)

MREE:

136173135(CASR)

OVR:	110146979(CASR)

MBEZ:

129550635(CASR)

SSC:	100520980(CASR)

CFR:	102504794(CASR)

CBAI:

105081618(CASR)

CDK:	105090302(CASR)

VPC:	102528218(CASR)

BACU:

102999890(CASR)

BMUS:

118894945(CASR)

LVE:	103091448(CASR)

OOR:	101289504(CASR)

LALB:

132520574(CASR)

DLE:	111171431(CASR)

PCAD:

102978777(CASR)

PSIU:

116753244(CASR)

NASI:

112416028(CASR)

ECB:	100034084(CASR)

EPZ:	103548438(CASR)

EAI:	106823746(CASR)

MYB:	102240037(CASR)

MYD:	102768966(CASR)

MMYO:

118677483(CASR)

MLF:	102437595(CASR)

MDT:	132230355(CASR)

MYUM:

139003891(CASR)

PKL:	118723844(CASR)

EFUS:

103290741(CASR)

MNA:	107527344(CASR)

DRO:	112320579(CASR)

SHON:

118990753(CASR)

AJM:	119046980(CASR)

PDIC:

114491093(CASR)

PHAS:

123827095(CASR)

MMF:	118617392(CASR)

PPAM:

129071709(CASR)

HAI:	109386938(CASR)

RFQ:	117035500(CASR)

PALE:

102886543(CASR)

PGIG:

120586696(CASR)

PVP:	105299330(CASR)

RAY:	107497789(CASR)

MJV:	108407427(CASR)

TOD:	119257474(CASR)

SARA:

101554387(CASR)

SFUM:

130018647(CASR)

SETR:

126026173(CASR)

LAV:	100671950(CASR)

TMU:

101344617

ETF:	101644174(CASR)

DNM:	101412395(CASR)

MDO:	100018274(CASR)

GAS:	123239465(CASR)

SHR:	100923241(CASR)

AFZ:

127554131

PCW:	110208103(CASR)

TVP:	118839168(CASR)

PBRV:

138154656(CASR)

OAA:	100085595(CASR)

TACU:

119938413(CASR)

GGA:	418266(CASR)

PCOC:

116239989(CASR)

MGP:	104909275(CASR)

CJO:	107318997(CASR)

TPAI:

128089874(CASR)

LMUT:

125685059(CASR)

NMEL:

110398790(CASR)

APLA:

101794634(CASR)

ACYG:

106049285(CASR)

CATA:

118259814(CASR)

AFUL:

116502187(CASR)

TGU:	100223057(CASR)

LSR:	110480710(CASR)

SCAN:

103827139(CASR)

PMOA:

120506515(CASR)

OTC:	121339283(CASR)

PRUF:

121351642(CASR)

ATRC:

139592863(CASR)

GFR:	102037483(CASR)

FAB:	101816726(CASR)

OMA:	130258689(CASR)

PHI:	102101160(CASR)

PMAJ:

107199856(CASR)

CCAE:

111938543(CASR)

CCW:	104687109(CASR)

CBRC:

103613935(CASR)

ACOE:

138112249(CASR)

ETL:	114058185(CASR)

ZAB:	102062004(CASR)

ZLE:	135452695(CASR)

ACHL:

103808701

SVG:	106857829(CASR)

MMEA:

130582284(CASR)

HRT:	120749573(CASR)

SATI:

136375579(CASR)

CCIC:

134056415(CASR)

FPG:	101921216(CASR)

FCH:	102052191(CASR)

CCRI:

104163946(CASR)

NNT:	104401542(CASR)

SHAB:

115601661(CASR)

ACUN:

113486688(CASR)

TALA:

104362532(CASR)

ACHC:

115344088(CASR)

HALD:

104322147(CASR)

HLE:	104831739(CASR)

AGEN:

126049086

HHAR:

128145233(CASR)

GCL:

127014496

CSTI:

104554445(CASR)

LDI:	104345105(CASR)

MNB:	103773103(CASR)

DPUB:

104298409(CASR)

PPUS:

135175190(CASR)

AVIT:

104276532(CASR)

BRHI:

104500225(CASR)

EGZ:	104126522(CASR)

NNI:	104008613(CASR)

PCRI:

104034770(CASR)

PCAO:

104050948

PADL:

103921166(CASR)

AFOR:

103905435(CASR)

FGA:	104080270(CASR)

GSTE:

104260144

CLV:	102088012(CASR)

MUI:	104545028(CASR)

PGUU:

104467239

PLET:

104619479

CMAC:

104479497(CASR)

CUCA:

104055668(CASR)

TEO:

104378603

BREG:

104636648(CASR)

OHA:	104327337(CASR)

ACAR:

104522824

CPEA:

104384973(CASR)

CVF:	104293574(CASR)

RTD:	128904391(CASR)

CRID:

134523710(CASR)

AAM:	106497195(CASR)

AROW:

112963960(CASR)

NPD:	112960119(CASR)

TGT:	104574634(CASR)

DNE:	112985913(CASR)

SCAM:

104150693(CASR)

ASN:

102382107

AMJ:	102575409(CASR)

CPOO:

109316224(CASR)

GGN:	109296607(CASR)

PSS:	102454429(CASR)

CMY:	102946726(CASR)

CCAY:

125622166(CASR)

DCC:	119859561(CASR)

CPIC:

101949569(CASR)

TST:	117886175(CASR)

CABI:

116816274(CASR)

MRV:	120385079(CASR)

ACS:	100561507(casr)

ASAO:

132767524(CASR)

PVT:	110084625(CASR)

SUND:

121920483(CASR)

PBI:	103050985(CASR)

PMUR:

107285802(CASR)

CTIG:

120306122

TSR:	106550537(CASR)

PGUT:

117661839(CASR)

APRI:

131191601(CASR)

PTEX:

113444508(CASR)

NSS:	113417239(CASR)

VKO:	123033213(CASR)

PMUA:

114587867(CASR)

PRAF:

128404586(CASR)

ZVI:	118097843(CASR)

HCG:	128329275 128329918 128331331 128336250 128348202(CASR)

GJA:	107114860(CASR)

STOW:

125436644

EMC:	129345612(CASR)

XLA:	108709291(casr.S)

XTR:	100496505(casr)

NPR:	108801946(CASR)

RTEM:

120928071(CASR)

BBUF:

120994365(CASR)

BGAR:

122930619(CASR)

PWL:	138248837(CASR)

MUO:	115470636(CASR) 115471368

GSH:	117358748(CASR)

DRE:	560607(casr)

SRX:	107719763(casr) 107752249

SANH:

107662088 107702888

SGH:	107557750 107560313

CCAR:

109059878 109106310

CAUA:

113085850 113094305

CGIB:

127958894 127991348

PTET:

122324474(casr)

LROH:

127165949(casr)

OMC:	131540382(casr)

PPRM:

120471748(casr)

RKG:	130082525(casr)

MAMB:

125267780(casr)

CIDE:

127512949

CERY:

137034402(casr)

MASI:

127425971 127437166

TROS:

130546546(casr)

TDW:	130419622(casr)

MANU:

129441092(casr)

PDAB:

135774389(casr)

IPU:

108260132

IFU:	128603801(casr)

PHYP:

113531355(casr)

SMEO:

124378849(casr)

TFD:	113650874(casr)

TVC:	132841029(casr)

CGAR:

128512431(casr)

NGRA:

132875460(casr)

TRN:	134303744(casr)

AMEX:

103045396(casr)

CMAO:

118815114(casr)

EEE:	113587436(casr)

CHAR:

105904387(casr)

SPIL:

134080858(casr)

TRU:	101080211(casr)

TFS:	130537418(casr)

TNG:	GSTEN00019045G001

LCO:	104935625(casr)

NCC:	104966000(casr)

TBEN:

117490760(casr)

CGOB:

115019028(casr)

PGEO:

117459110(casr)

GACU:

117536792(casr)

EMAC:

134872226(casr)

ELY:	117247108(casr)

EFO:	125897800(casr)

PLEP:

121952867(casr)

SLUC:

116064708(casr)

ECRA:

117956092(casr)

ESP:	116700055(casr)

PFLV:

114567291(casr)

GAT:	120821234(casr)

PPUG:

119215493(casr)

AFB:	129114033(casr)

CLUM:

117742719(casr)

PSWI:

130191906(casr)

CANA:

137802978(casr)

CVE:	137876739(casr)

MSAM:

119894870(casr)

SCHU:

122887902(casr)

CUD:	121518800(casr)

SPUL:

138604828(casr)

LMIX:

132987827(casr)

ALAT:

119031745(casr)

ASTR:

137606634(casr)

MZE:	101466083(casr)

ONL:	100711199(casr)

OAU:	116336145(casr)

OLA:	101160185(casr)

OML:	112142737(casr)

CSAI:

133460245(casr)

XMA:	102233243(casr)

XCO:	114153427(casr)

XHE:	116728643(casr)

PRET:

103475411(casr)

PFOR:

103141635(casr)

PLAI:

106959937(casr)

PMEI:

106911342(casr)

GAF:	122844844(casr)

PPRL:

129368737(casr)

CVG:	107096676(casr)

CTUL:

119777945(casr)

GMU:	124876744(casr)

NFU:	107386425(casr)

KMR:	108236954(casr)

ALIM:

106532727

NWH:	119420188(casr)

AOCE:

111587194(casr)

EJA:	138195946(casr)

BFRE:

138629526(casr)

MCEP:

125021337(casR)

CSEM:

103395578(casr)

POV:	109628817(casr)

SSEN:

122779974(casr)

SSOE:

131458018(casr)

HHIP:

117774908(casr)

HSP:	118122291(casr)

PPLT:

128456960(casr)

SMAU:

118301519(casr)

LCF:

108893522

SDU:	111234605(casr)

SLAL:

111666288(casr)

XGL:	120802747(casr)

HCQ:	109517814(casr) 109517819

SSCV:

125982004(casr)

SBIA:

133491367 133491469 133491919

PEE:	133415958(casr)

PTAO:

133467112(casr)

BPEC:

110158605(casr)

ENY:	140360349(casr)

MALB:

109959556(casr)

BSPL:

114869412(casr)

SJO:	128371477(casr)

SSCO:

133994271(casr)

GMH:	115546653(casr)

SASA:

100136437(casr) 100136909 100136912

STRU:

115204410(casr)

OTW:	112231207(casr)

OMY:	110510087(casr)

OGO:	124007306(casr)

ONE:	115116497(casr)

OKI:	109874249(casr)

OKE:	118385024(casr)

OMM:	135544182(casr)

OCLA:

139388622

SALP:

111964284(casr)

SNH:	120020906(casr)

CCLU:

121541251(casr)

ELS:	105010874(casr)

OEP:	134014016(casr)

PKI:	111855344(casr)

LOC:	102693201(casr)

PSPA:

121302642(casr)

ARUT:

117406287 117972889

PSEX:

120524387(casr)

LCM:	102364749(CASR)

CMK:	103188650(casr)

RTP:

109913689

CPLA:

122555215(casr)

HOC:	132820790(casr)

LERI:

129702527(casr)

PMRN:

LRJ:

BFO:

BBEL:

CIN:

SCLV:

SPU:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:	100313567(Casr1) 100368557 100371662 102800571

PFLL:

139117585 139117586 139117588 139117589 139117590 139120801

OBI:

OSN:

LJP:

LLON:

NVE:	116612387 5504714 5509807 5509900 5514145 5514586 5514640 5514641 5514718 5514719 5514745 5515018 5515863 5517778 5517886 5518169

EPA:	110237588 110248447 110248561 110248599 110248609

ATEN:

116286459 116286465 116286513 116289906 116291835 116296554 116297090 116301787 116301808 116306926

ADF:	107327952 107340859 107340895 107344791 107349098

AMIL:

114954111 114954604 114954643 114956530 114961867 114964946 114964969

MCAZ:

138022758 138032986 138033293 138035189 138038964 138043494 138052695 138052697 138052698 138052699 138052700 138054238

MFOO:

137973070 137992556 137994519 137995292 137996884 137996885 137996887 138003097 138003099 138003100 138006882

PDAM:

113665737 113666847 113668928 113670073 113670172 113670470 113670471 113670472 113672586 113674028 113677976 113677977 113678004 113678992 113682279 113683555 113685200

SPIS:

111319565 111320548 111322916 111323721 111323977 111328116 111328379 111329544 111329695 111329855 111337045 111338291 111338590 111340143 111346050 111346057 111346159

DGT:	114527475 114527490 114536276

XEN:	124433344 124433347 124433441 124453945

HMG:	100198468 100201161 101239077 101239579 105846088 105846111

HSY:	130630362 130645154 130645155 130646099 130646996 130646997 130647954 130649619 130654434 130654920

RES:	135690068 135690102 135695871

TAD:	TRIADDRAFT_10902 TRIADDRAFT_11108 TRIADDRAFT_11320 TRIADDRAFT_29555 TRIADDRAFT_59571

» show all

Reference

PMID:7759551

Authors

Garrett JE, Capuano IV, Hammerland LG, Hung BC, Brown EM, Hebert SC, Nemeth EF, Fuller F

Title

Molecular cloning and functional expression of human parathyroid calcium receptor cDNAs.

Journal

J Biol Chem 270:12919-25 (1995)
DOI:10.1074/jbc.270.21.12919

Sequence

[hsa:846]

LinkDB

DBGET integrated database retrieval system