KEGG   DRUG: Tamolarizine hydrochloride
Entry
D11102                      Drug                                   
Name
Tamolarizine hydrochloride (JAN)
Formula
C27H32N2O3. 2HCl
Exact mass
504.1946
Mol weight
505.4765
Structure
Efficacy
Vasodilator (cerebral), Calcium channel blocker
Target
CACNA1-L [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
  Pathway
hsa04020  Calcium signaling pathway
hsa04024  cAMP signaling pathway
hsa04270  Vascular smooth muscle contraction
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Calcium channels
    CACNA1-L
     D11102  Tamolarizine hydrochloride (JAN)
Other DBs
CAS: 93035-33-7
PubChem: 376219026
LinkDB
KCF data

ATOM        34
            1   C8x C    10.6400  -21.7700
            2   C8x C    11.8300  -21.0700
            3   C8y C    11.8300  -19.6700
            4   C8x C    10.5700  -18.9700
            5   C8x C     9.3800  -19.6700
            6   C8x C     9.3800  -21.0700
            7   C1c C    13.0200  -18.9000
            8   C8y C    14.2800  -19.6000
            9   N1y N    13.0200  -17.5700
            10  C8x C    14.2800  -21.0000
            11  C8x C    15.4700  -21.7000
            12  C8x C    16.6600  -21.0000
            13  C8x C    16.6600  -19.6000
            14  C8x C    15.4700  -18.9000
            15  C1x C    14.2100  -16.8000
            16  C1x C    14.2100  -15.4000
            17  N1y N    13.0200  -14.7700
            18  C1x C    11.7600  -15.4700
            19  C1x C    11.7600  -16.8700
            20  C1b C    13.0200  -13.3700
            21  C1c C    14.2100  -12.6700
            22  O1a O    15.4000  -13.3700
            23  C8y C    14.2100  -11.2700
            24  C8x C    15.4000  -10.5700
            25  C8y C    15.4000   -9.1700
            26  C8y C    14.2100   -8.4700
            27  C8x C    13.0200   -9.1700
            28  C8x C    13.0200  -10.5700
            29  O2a O    14.2100   -7.0700
            30  O2a O    16.6153   -8.4749
            31  C1a C    17.8037   -9.1677
            32  C1a C    15.4224   -6.3700
            33  X   Cl   18.9700  -16.8700
            34  X   Cl   18.9700  -16.8700
BOND        35
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     3   7 1
            8     7   8 1
            9     7   9 1
            10    8  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14   13  14 2
            15    8  14 1
            16    9  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21    9  19 1
            22   17  20 1
            23   21  22 1
            24   21  20 1
            25   21  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   23  28 1
            32   26  29 1
            33   25  30 1
            34   30  31 1
            35   29  32 1
BRACKET     1    17.2900  -17.7100   17.2900  -15.6100
            1    20.0200  -15.6100   20.0200  -17.7100
            1  2
 ORIGINAL  1   33
 REPEAT    1   34

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