KEGG   DRUG: Aspirin and omeprazole
Entry
D11616            Mixture   Drug                                   
Name
Aspirin and omeprazole;
Yosprala (TN)
Product
Component
Aspirin [DR:D00109], Omeprazole [DR:D00455]
Class
Metabolizing enzyme substrate
 DG01639  CYP2C19 substrate
 DG01633  CYP3A/CYP3A4 substrate
  DG02913  CYP3A4 substrate
Remark
Product: D11616<US>
Efficacy
Anti-ulcerative
Comment
Prevention of aspirin-associated gastric ulcers
Omeprazole is metabolized by CYP2C19 with some contribution from CYP3A4.
Metabolism
Enzyme: CYP2C19 [HSA:1557]; CYP3A4 [HSA:1576]
Interaction
Brite
Drug groups [BR:br08330]
 Metabolizing enzyme substrate
  DG01639  CYP2C19 substrate
   D11616  Aspirin and omeprazole
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D11616  Aspirin and omeprazole
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D11616
Other DBs
CAS: 1259513-22-8
PubChem: 405226483
LinkDB

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