| Entry |
|
|---|
| Name |
Bendamustine hydrochloride hydrate (JAN);
Bendamustine hydrochloride monohydrate;
Treakisym (TN) |
|---|
| Formula |
C16H21Cl2N3O2. HCl. H2O
|
|---|
| Exact mass |
411.0883
|
|---|
| Mol weight |
412.73
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
|
|---|
| Remark |
| Therapeutic category: | 4219 |
| Product (DG00678): | D07085<JP/US> D11661<JP> |
|
|---|
| Efficacy |
Antineoplastic, Alkylating agent |
|---|
| Target |
DNA |
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01A ALKYLATING AGENTS
L01AA Nitrogen mustard analogues
L01AA09 Bendamustine
D11661 Bendamustine hydrochloride hydrate (JAN) <JP>
USP drug classification [BR:br08302]
Antineoplastics
Alkylating Agents
Nitrogen Mustards
Bendamustine
D11661 Bendamustine hydrochloride hydrate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
421 Alkylating agents
4219 Others
D11661 Bendamustine hydrochloride hydrate (JAN)
Drug groups [BR:br08330]
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
DG00678 Bendamustine
D11661 Bendamustine hydrochloride hydrate
Drug groups [BR:br08330]
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
DG00678 Bendamustine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 25
1 C8y C 15.0648 -15.6955
2 N1c N 13.9437 -16.3962
3 C1b C 13.9437 -17.7275
4 C1b C 12.6825 -15.6955
5 C1b C 12.6825 -14.2240
6 X Cl 11.4913 -13.5233
7 C1b C 15.1349 -18.4282
8 X Cl 15.1349 -19.8295
9 C8x C 16.3261 -16.3962
10 C8y C 17.5173 -15.6955
11 C8y C 17.5173 -14.2941
12 C8x C 16.2560 -13.5934
13 C8x C 15.0648 -14.2941
14 N5x N 18.8486 -16.1159
15 C8y C 19.6894 -14.9948
16 N4y N 18.8486 -13.8036
17 C1b C 21.0908 -14.9948
18 C1b C 21.7915 -16.1859
19 C1b C 23.1928 -16.1859
20 C6a C 23.8935 -17.3771
21 O6a O 25.2949 -17.3771
22 O6a O 23.1928 -18.6384
23 C1a C 19.2690 -12.5424
24 X Cl 25.7854 -13.3131
25 O0 O 26.2500 -15.3300
BOND 24
1 1 2 1
2 2 3 1
3 2 4 1
4 4 5 1
5 5 6 1
6 3 7 1
7 7 8 1
8 1 9 2
9 9 10 1
10 10 11 2
11 11 12 1
12 12 13 2
13 1 13 1
14 10 14 1
15 14 15 2
16 15 16 1
17 11 16 1
18 15 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 20 22 2
24 16 23 1
|
|---|
