KEGG   DRUG: Bendamustine hydrochloride
Entry
D07085                      Drug                                   

Name
Bendamustine hydrochloride (JAN/USAN);
Treanda (TN);
Ribomustin (TN)
Product
Formula
C16H21Cl2N3O2. HCl
Exact mass
393.0778
Mol weight
394.7238
Structure
Simcomp
Class
Antineoplastic
 DG01677  Alkylating agent
  DG01678  Nitrogen mustard analog
Remark
Therapeutic category: 4219
ATC code: L01AA09
Chemical structure group: DG00678
Product (DG00678): D07085<JP/US> D11661<JP>
Efficacy
Antineoplastic, Alkylating agent
  Disease
Chronic lymphocytic leukemia [DS:H00005]
Non-Hodgkin lymphoma [DS:H02418]
Target
DNA
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01A ALKYLATING AGENTS
    L01AA Nitrogen mustard analogues
     L01AA09 Bendamustine
      D07085  Bendamustine hydrochloride (JAN/USAN) <JP/US>
USP drug classification [BR:br08302]
 Antineoplastics
  Alkylating Agents
   Bendamustine
    D07085  Bendamustine hydrochloride (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   421  Alkylating agents
    4219  Others
     D07085  Bendamustine hydrochloride (JAN/USAN)
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D07085
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D07085
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D07085
Other DBs
CAS: 3543-75-7
PubChem: 51091427
ChEMBL: CHEMBL1201734
LigandBox: D07085
NIKKAJI: J327.616C
LinkDB
KCF data

ATOM        24
            1   C8y C    15.1026  -15.7232
            2   N1c N    13.9801  -16.4247
            3   C1b C    13.9800  -17.7577
            4   C1b C    12.7173  -15.7232
            5   C1b C    12.7173  -14.2498
            6   X   Cl   11.5246  -13.5483
            7   C1b C    15.1728  -18.4593
            8   X   Cl   15.1728  -19.8625
            9   C8x C    16.3218  -16.4177
            10  C8y C    17.5329  -15.7092
            11  C8y C    17.5249  -14.3061
            12  C8x C    16.3056  -13.6115
            13  C8x C    15.0946  -14.3200
            14  N5x N    18.8699  -16.1351
            15  C8y C    19.6882  -14.9952
            16  N4y N    18.8569  -13.8648
            17  C1b C    21.0657  -14.9878
            18  C1b C    21.7889  -16.2242
            19  C1b C    23.1708  -16.2163
            20  C6a C    23.8785  -17.4259
            21  O6a O    25.2756  -17.4178
            22  O6a O    23.1906  -18.6333
            23  C1a C    19.2765  -12.5498
            24  X   Cl   25.7667  -13.3378
BOND        24
            1     1   2 1
            2     2   3 1
            3     2   4 1
            4     4   5 1
            5     5   6 1
            6     3   7 1
            7     7   8 1
            8     1   9 2
            9     9  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13    1  13 1
            14   10  14 1
            15   14  15 2
            16   15  16 1
            17   11  16 1
            18   15  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   20  22 2
            24   16  23 1

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