KEGG   DRUG: Fosdenopterin
Entry
D11779                      Drug                                   

Name
Fosdenopterin (USAN)
Formula
C10H14N5O8P
Exact mass
363.058
Mol weight
363.2206
Structure
Remark
Chemical structure group: DG03102
Product (DG03102): D11780<US>
Efficacy
Cofactor replacement
Comment
Cofactor replacement therapy
Treatment of molybdenum cofactor deficiency, type A
Target
MOCS1* [HSA_VAR:4337v1] [HSA:4337] [KO:K20967]
  Network
N10026  Replacement of cofactor cPMP for deficient MOCS1
  Pathway
hsa00790  Folate biosynthesis
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases (EC4)
   Moco biosynthesis enzyme
    MOCS1* [HSA_VAR:4337v1]
     D11779  Fosdenopterin (USAN)
Other DBs
CAS: 150829-29-1
PubChem: 405226645
ChEMBL: CHEMBL2338675
LinkDB
KCF data

ATOM        24
            1   C8y C    19.8100  -18.9700
            2   C8y C    19.8100  -17.5700
            3   C8y C    18.6200  -16.8700
            4   N5x N    17.3600  -17.5700
            5   C8y C    17.3600  -18.9700
            6   N4x N    18.6200  -19.6700
            7   N1x N    21.0000  -19.6700
            8   C1y C    22.2600  -18.9700
            9   C1y C    22.2600  -17.5700
            10  N1x N    21.0000  -16.8700
            11  O2x O    23.4500  -19.6700
            12  C1y C    24.6400  -18.9700
            13  C1y C    24.6400  -17.5700
            14  C1z C    23.4500  -16.8700
            15  C1x C    25.9000  -19.6700
            16  O2x O    27.0900  -18.9700
            17  P1b P    27.0900  -17.5700
            18  O2x O    25.9000  -16.8700
            19  O5x O    18.6200  -15.4700
            20  O1a O    24.1500  -15.6800
            21  O1a O    22.7500  -15.6800
            22  O1c O    28.2800  -18.2700
            23  O1c O    27.0900  -16.1700
            24  N1a N    16.1700  -19.6700
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    2  10 1
            12    8  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16    9  14 1
            17   12  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   13  18 1
            22    3  19 2
            23   14  20 1
            24   14  21 1
            25   17  22 1
            26   17  23 2
            27    5  24 1

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