Homo sapiens (human): 4337 Help Entry 4337              CDS       T01001                                  Symbol MOCS1, MIG11, MOCOD, MOCS1A, MOCS1B Name (RefSeq) molybdenum cofactor synthesis 1   KO K20967   GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase [EC:4.1.99.22 4.6.1.17] Organism hsa  Homo sapiens (human) Pathway hsa00790   Folate biosynthesis hsa01100   Metabolic pathways hsa01240   Biosynthesis of cofactors Module hsa_M00880   Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor Network nt06025  Molybdenum cofactor biosynthesis   Element N00890   Molybdenum cofactor biosynthesis N10026   Replacement of cofactor cPMP for deficient MOCS1 Disease H02311   Molybdenum cofactor deficiency Drug target Fosdenopterin (DG03102):  D11779 D11780<US> Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     4337 (MOCS1) Enzymes [BR:hsa01000]  4. Lyases   4.1  Carbon-carbon lyases    4.1.99  Other carbon-carbon lyases     4.1.99.22  GTP 3',8-cyclase      4337 (MOCS1)   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.17  cyclic pyranopterin monophosphate synthase      4337 (MOCS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Mob_synth_C Radical_SAM Fer4_12 Fer4_14 Radical_SAM_2 Motif Other DBs NCBI-GeneID:  4337 NCBI-ProteinID:  NP_001068566 OMIM:  603707 HGNC:  7190 Ensembl:  ENSG00000124615 Pharos:  Q9NZB8(Tbio) UniProt:  Q9NZB8 A0A024RD17 LinkDB All DBs Position 6:complement(39904170..39934462) Genome browser AA seq 385 aa AA seqDB search MAARPLSRMLRRLLRSSARSCSSGAPVTQPCPGESARAASEEVSRRRQFLREHAAPFSAF LTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLLTTEEILTLARLFVKEGID KIRLTGGEPLIRPDVVDIVAQLQRLEGLRTIGVTTNGINLARLLPQLQKAGLSAINISLD TLVPAKFEFIVRRKGFHKVMEGIHKAIELGYNPVKVNCVVMRGLNEDELLDFAALTEGLP LDVRFIEYMPFDGNKWNFKKMVSYKEMLDTVRQQWPELEKVPEEESSTAKAFKIPGFQGQ ISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLRAGASEQELLRIIGAAVG RKKRQHAGMFSISQMKNRPMILIGG NT seq 1158 nt NT seq  +upstreamnt  +downstreamnt atggcggcgcggccactgtcccggatgctgcggcggcttctgaggtccagcgcccggagc tgcagctcaggggctccggtgacccagccctgccccggggagtccgcgcgagctgcctcg gaggaggtgtccaggcggaggcagttcctgcgggagcatgcggcccccttctccgccttc ctcacagacagcttcggccggcagcacagctacctgcggatctccctcacagagaagtgc aacctcagatgtcagtactgcatgcccgaggagggggtcccgctgacccccaaagccaac ctgctgaccacagaggagatcctgaccctcgcccggctctttgtgaaggaaggcatcgac aagatccggctcacaggtggagagccgcttatccggccggacgtggtggacattgtggcc cagctccagcggctggaagggctgagaaccataggtgttaccaccaatggcatcaacctg gcccggctactgccccagcttcagaaggctggtctcagtgccatcaacatcagcctggac accctggtgcctgccaagtttgagttcattgtccgcaggaaaggcttccacaaggtcatg gagggcatccacaaggccatcgagctgggctacaaccctgtgaaggtgaactgtgtggtg atgcgaggccttaacgaggatgaactcctggactttgcggccttgactgagggcctcccc ctggatgtgcgcttcatagagtatatgccctttgatggcaacaagtggaacttcaagaag atggtcagctataaggagatgctagacactgtccggcagcagtggccagagctggagaag gtgccagaggaggaatccagcacagccaaggcctttaaaatccctggcttccaaggccag atcagcttcatcacatccatgtctgagcatttctgtgggacctgcaaccgcctgcgaatc acagctgatgggaacctcaaggtctgcctctttggaaactctgaggtatccctgcgggat cacctgcgagctggggcctctgagcaggagctgctgagaatcattggggctgctgtgggc aggaagaagcggcagcatgcaggcatgttcagtatttcccagatgaagaaccggcccatg atcctcatcggtgggtga

DBGET integrated database retrieval system