| Entry |
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| Symbol |
MOCS1
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| Name |
GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase [EC: 4.1.99.22 4.6.1.17]
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| Pathway |
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| Module |
| M00880 | Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor |
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| Reaction |
| R09394 | GTP 3',8-cyclase [(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate-forming] |
| R11372 | (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate lyase (cyclic pyranopterin phosphate-forming) |
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| Disease |
| H02311 | Molybdenum cofactor deficiency |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
K20967 MOCS1; GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase
Enzymes [BR:ko01000]
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.22 GTP 3',8-cyclase
K20967 MOCS1; GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.17 cyclic pyranopterin monophosphate synthase
K20967 MOCS1; GTP 3',8-cyclase / cyclic pyranopterin monophosphate synthase
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| Other DBs |
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| Genes |
» show all
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| Reference |
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| Authors |
Hanzelmann P, Schwarz G, Mendel RR |
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| Title |
Functionality of alternative splice forms of the first enzymes involved in human molybdenum cofactor biosynthesis. |
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| Journal |
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| Sequence |
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| LinkDB |
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