| Entry |
|
|---|
| Name |
Trazpiroben (USAN/INN) |
|---|
| Formula |
C31H39N3O4
|
|---|
| Exact mass |
517.2941
|
|---|
| Mol weight |
517.66
|
|---|
| Structure |
|
|---|
| Efficacy |
Prokinetic, Dopamine receptor antagonist |
|---|
| Comment |
Treatment of gastrointestinal (GI) motility disorders
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D11982 Trazpiroben (USAN/INN)
DRD3
D11982 Trazpiroben (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 38
1 C8x C 8.6102 -23.4505
2 C8x C 8.6102 -24.8506
3 C8x C 9.8003 -25.5506
4 C8x C 11.0603 -24.8506
5 C8y C 11.0603 -23.4505
6 C8x C 9.8003 -22.7505
7 C5a C 12.2504 -22.7505
8 C1b C 13.4404 -23.4505
9 O5a O 12.2504 -21.3505
10 C1b C 14.6304 -22.7505
11 C1b C 15.8205 -23.4505
12 N1y N 17.0105 -22.7505
13 C1x C 18.2005 -23.4505
14 C1x C 19.4606 -22.7505
15 C1z C 19.4606 -21.3505
16 C1x C 18.2706 -20.6504
17 C1x C 17.0105 -21.3505
18 C5x C 19.4606 -19.9504
19 N1y N 20.7906 -21.7705
20 C1x C 21.6307 -20.6504
21 N1y N 20.7906 -19.5304
22 O5x O 18.3308 -19.1224
23 C1y C 20.7906 -23.1705
24 C1x C 19.5779 -23.8706
25 C1x C 19.5779 -25.2706
26 C1x C 20.7904 -25.9706
27 C1x C 22.0031 -25.2705
28 C1x C 22.0031 -23.8705
29 C1b C 21.2187 -18.1973
30 C8y C 22.6187 -18.1973
31 C8x C 23.3177 -19.4080
32 C8x C 24.7177 -19.4080
33 C8y C 25.4177 -18.1955
34 C8x C 24.7187 -16.9848
35 C8x C 23.3187 -16.9848
36 C6a C 26.8100 -18.1956
37 O6a O 27.5081 -16.9865
38 O6a O 27.5119 -19.4113
BOND 42
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 7 9 2
10 8 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 12 17 1
19 18 15 1
20 15 19 1
21 19 20 1
22 20 21 1
23 18 21 1
24 18 22 2
25 19 23 1
26 23 24 1
27 24 25 1
28 25 26 1
29 26 27 1
30 27 28 1
31 23 28 1
32 21 29 1
33 29 30 1
34 30 31 2
35 31 32 1
36 32 33 2
37 33 34 1
38 34 35 2
39 30 35 1
40 33 36 1
41 36 37 2
42 36 38 1
|
|---|
