| Entry |
|
|---|
| Name |
Seralutinib (USAN/INN) |
|---|
| Formula |
C27H27N5O3
|
|---|
| Exact mass |
469.2114
|
|---|
| Mol weight |
469.53
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
|
|---|
| Efficacy |
Receptor tyrosine kinase inhibitor |
|---|
| Comment |
Treatment of pulmonary arterial hypertension
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
D12002 Seralutinib
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
PDGFR family
PDGFR
D12002 Seralutinib (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 35
1 C8x C 7.7700 -12.3200
2 C8y C 7.7700 -13.7200
3 C8x C 8.9824 -14.4200
4 C8y C 10.1949 -13.7200
5 C8x C 10.1949 -12.3200
6 N5x N 8.9824 -11.6200
7 C5a C 11.4260 -14.4310
8 N1b N 12.6312 -13.7353
9 O5a O 11.4257 -15.8199
10 C8y C 13.8135 -14.4181
11 C8x C 13.8134 -15.8198
12 C8x C 15.0258 -16.5199
13 C8x C 16.2383 -15.8200
14 C8y C 16.2384 -14.4183
15 C8x C 15.0260 -13.7182
16 C1c C 17.4514 -13.7182
17 N1b N 18.6484 -14.4096
18 C8y C 19.8351 -13.7246
19 N5x N 21.0265 -14.4128
20 C8y C 22.2391 -13.7131
21 C8x C 22.2394 -12.3131
22 N5x N 21.0480 -11.6249
23 C8x C 19.8354 -12.3246
24 C8y C 23.4700 -14.4242
25 C8x C 23.4696 -15.8199
26 C8x C 24.6818 -16.5202
27 C8y C 25.8944 -15.8206
28 C8y C 25.8949 -14.4250
29 C8x C 24.6827 -13.7246
30 O2a O 27.1135 -13.7219
31 C1a C 28.3072 -14.4117
32 O2a O 27.1105 -16.5233
33 C1a C 28.3091 -15.8316
34 C1a C 17.4515 -12.3202
35 C1a C 6.5576 -14.4200
BOND 38
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 7 9 2
10 8 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 14 15 2
16 10 15 1
17 14 16 1
18 16 17 1
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 18 23 1
26 20 24 1
27 24 25 2
28 25 26 1
29 26 27 2
30 27 28 1
31 28 29 2
32 24 29 1
33 28 30 1
34 30 31 1
35 27 32 1
36 32 33 1
37 16 34 1 #Down
38 2 35 1
|
|---|
