KEGG   DRUG: Patritumab deruxtecan
Entry
D12184                      Drug                                   
Name
Patritumab deruxtecan (USAN/INN);
Patritumab deruxtecan (genetical recombination) (JAN)
Formula
C6542H10072N1740O2038S40. (C52H56FN9O13)n
Remark
ATC code: L01FX36
Efficacy
Antineoplasitc
  Type
Antibody-drug conjugate
Target
ERBB3 (HER3) [HSA:2065] [KO:K05084]
TOP1 [HSA:7150] [KO:K03163]
  Pathway
hsa04010  MAPK signaling pathway
hsa04012  ErbB signaling pathway
hsa04151  PI3K-Akt signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01F MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES
    L01FX Other monoclonal antibodies and antibody drug conjugates
     L01FX36 Patritumab deruxtecan
      D12184  Patritumab deruxtecan (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Receptor tyrosine kinases (RTK)
   EGFR family
    ERBB3 (HER3)
     D12184  Patritumab deruxtecan (USAN/INN)
 Enzymes
  Isomerases (EC5)
   DNA topoisomerase
    TOP1
     D12184  Patritumab deruxtecan (USAN/INN)
Other DBs
CAS: 2227102-46-5
PubChem: 497620597
LinkDB

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