| Entry |
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| Name |
Dordaviprone (USAN/INN) |
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| Formula |
C24H26N4O
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| Exact mass |
386.2107
|
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| Mol weight |
386.49
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| Structure |
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| Class |
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| Remark |
| Product (DG03280): | D12734<US> |
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| Efficacy |
Antineoplastic |
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| Target |
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]; CYP2B6 [HSA: 1555], CYP2C8 [HSA: 1558], CYP2C9 [HSA: 1559], CYP2D6 [HSA: 1565], CYP3A5 [HSA: 1577]
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| Interaction |
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| Brite |
Drug groups [BR:br08330]
Metabolizing enzyme substrate
DG02919 CYP2B6 substrate
DG03280 Dordaviprone
D12733 Dordaviprone
DG02918 CYP2C8 substrate
DG03280 Dordaviprone
D12733 Dordaviprone
DG01642 CYP2C9 substrate
DG03280 Dordaviprone
D12733 Dordaviprone
DG01644 CYP2D6 substrate
DG03280 Dordaviprone
D12733 Dordaviprone
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG03280 Dordaviprone
D12733 Dordaviprone
DG02925 CYP3A5 substrate
DG03280 Dordaviprone
D12733 Dordaviprone
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D12733 Dordaviprone (USAN/INN)
Peptidases and inhibitors
Serine peptidases
ClpP endopeptidase family
CLPP
D12733 Dordaviprone (USAN/INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D12733
Drug groups [BR:br08330]
Metabolizing enzyme substrate
DG02919 CYP2B6 substrate
DG03280 Dordaviprone
DG02918 CYP2C8 substrate
DG03280 Dordaviprone
DG01642 CYP2C9 substrate
DG03280 Dordaviprone
DG01644 CYP2D6 substrate
DG03280 Dordaviprone
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG03280 Dordaviprone
DG02925 CYP3A5 substrate
DG03280 Dordaviprone
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 29
1 C8y C 17.6338 -16.5867
2 C8y C 17.6338 -15.1926
3 C8y C 18.8188 -14.4955
4 N4y N 20.0735 -15.1926
5 C8y C 20.0735 -16.5867
6 N4y N 18.8188 -17.2838
7 C1x C 16.4488 -17.2838
8 C1x C 15.1940 -16.5867
9 N1y N 15.1940 -15.1926
10 C1x C 16.4488 -14.4955
11 C1b C 14.0090 -14.4955
12 C8y C 12.8240 -15.1926
13 C8x C 12.8240 -16.5867
14 C8x C 11.5693 -17.2838
15 C8x C 10.3843 -16.5867
16 C8x C 10.3843 -15.1926
17 C8x C 11.5693 -14.4955
18 O5x O 18.8188 -13.1014
19 C1b C 21.2585 -14.4955
20 C8y C 22.4435 -15.1926
21 C8y C 23.6286 -14.4955
22 C8x C 24.8833 -15.1926
23 C8x C 24.8833 -16.5867
24 C8x C 23.6983 -17.2838
25 C8x C 22.4435 -16.5867
26 C1a C 23.6286 -13.1014
27 N2x N 21.1191 -17.4929
28 C1x C 20.4917 -18.8173
29 C1x C 19.0976 -18.6779
BOND 33
1 1 2 2
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 2 10 1
12 9 11 1
13 11 12 1
14 12 13 2
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 12 17 1
20 3 18 2
21 4 19 1
22 19 20 1
23 20 21 2
24 21 22 1
25 22 23 2
26 23 24 1
27 24 25 2
28 20 25 1
29 21 26 1
30 5 27 2
31 27 28 1
32 28 29 1
33 6 29 1
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