| Entry |
|
|---|
| Name |
Fosigotifator sodium tromethamine (USAN) |
|---|
| Formula |
C25H26Cl2F2N2O9P. C4H11NO3. Na
|
|---|
| Exact mass |
781.1358
|
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| Mol weight |
782.48
|
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| Structure |
|
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| Remark |
|
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| Efficacy |
Antidepressant, Neurodegenerative diseases agent, eIF2B activator |
|---|
| Comment |
Treatment of vanishing white matter disease, amyotrophic lateral sclerosis and major depressive disorder
|
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| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Not elsewhere classified
Genetic information processing
Translation factor
EIF2B
D13119 Fosigotifator sodium tromethamine (USAN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 50
1 C8x C 8.7514 -18.4130
2 C8y C 8.7514 -19.8132
3 C8y C 9.9416 -20.5134
4 C8x C 11.2018 -19.8132
5 C8y C 11.2018 -18.4130
6 C8x C 9.9416 -17.7129
7 X Cl 7.6312 -20.5134
8 O2a O 12.4620 -17.7129
9 X F 9.9416 -21.9836
10 C1b C 13.7222 -18.4130
11 C5a C 14.9124 -17.7129
12 N1b N 16.1026 -18.4130
13 C1z C 17.3628 -17.7129
14 C1x C 18.5530 -18.4130
15 C1x C 19.8132 -17.7129
16 C1z C 19.8132 -16.2427
17 C1y C 18.6230 -15.4725
18 C1x C 17.3628 -16.2427
19 N1b N 21.0034 -15.4725
20 O5a O 14.9124 -16.2427
21 C8x C 28.4246 -15.4725
22 C8y C 28.4246 -14.0723
23 C8y C 27.1644 -13.3722
24 C8x C 25.9042 -14.0723
25 C8y C 25.9042 -15.4725
26 C8x C 27.1644 -16.2427
27 X Cl 29.5448 -13.3722
28 O2a O 24.7140 -16.2427
29 X F 27.1644 -11.9720
30 C1b C 23.4538 -15.4725
31 C5a C 22.1936 -16.2427
32 O5a O 22.1936 -17.7129
33 C1x C 19.3932 -17.1528
34 C1x C 18.4830 -17.7129
35 O2a O 18.6230 -14.0723
36 C1b C 19.8832 -13.3722
37 O2b O 19.8832 -11.9720
38 P1b P 21.0734 -11.2718
39 O1c O 22.3336 -10.5017
40 O1c O 21.7736 -12.4620
41 O1c O 20.3733 -10.0116 #-
42 Z Na 17.7100 -9.9400 #+
43 C1b C 26.4600 -18.9700
44 C1d C 27.6724 -19.6700
45 O1a O 25.2476 -19.6700
46 C1b C 28.8679 -18.9796
47 O1a O 30.0553 -19.6651
48 C1b C 27.6724 -21.0700
49 N1a N 27.6724 -18.2700
50 O1a O 28.8680 -21.7603
BOND 51
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 5 8 1
9 3 9 1
10 8 10 1
11 10 11 1
12 11 12 1
13 13 12 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 13 18 1
20 16 19 1
21 11 20 2
22 21 22 2
23 22 23 1
24 23 24 2
25 24 25 1
26 25 26 2
27 21 26 1
28 22 27 1
29 25 28 1
30 23 29 1
31 28 30 1
32 30 31 1
33 31 19 1
34 31 32 2
35 16 33 1
36 13 34 1
37 33 34 1
38 17 35 1 #Down
39 35 36 1
40 36 37 1
41 37 38 1
42 38 39 2
43 38 40 1
44 38 41 1
45 43 44 1
46 43 45 1
47 44 46 1
48 46 47 1
49 44 48 1
50 44 49 1
51 48 50 1
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