KEGG   DRUG: Donidalorsen sodium
Entry
D13154                      Drug                                   
Name
Donidalorsen sodium (USAN);
Dawnzera (TN)
Formula
C296H415N83Na20O151P20S15
Exact mass
9106.5863
Mol weight
9112.21
Sequence
  Type
Nucleotide
Efficacy
Antiangioedema, Plasma kallikrein inhibitor
  Disease
Hereditary angioedema [DS:H01006]
  Type
Antisense oligonucleotide
Comment
Treatment and/or prevention of hereditary angioedema
Target
KLKB1 (PKK) [HSA:3818] [KO:K01324] (mRNA)
  Pathway
hsa04610  Complement and coagulation cascades
  Network
nt06514  Coagulation cascade
Brite
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D13154
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D13154
Other DBs
CAS: 2304701-45-7
LinkDB

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