KEGG   DISEASE: Panic disorder
H01664                      Disease                                
Panic disorder
Panic disorder (PD) is a common type of anxiety disorder, characterized by unexpected and repeated panic attacks or fear of future panic attacks. It has a rapid onset and includes symptoms such as palpitations, chest pain, sweating and shaking. Some physical illnesses (e.g. asthma) commonly occur with panic disorder, and certain lifestyle factors (e.g. smoking) increase the risk for the disorder, but causal pathways are still unclear. In recent years, an association was found between panic symptoms and increased activity in the right frontal region of the brain. Genetic susceptibility factors also exist, but their exact nature and pathophysiological mechanisms remain unknown. Cognitive behavioural therapy (CBT) and several medications, including selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and benzodiazepines are effective for PD. Among these, SSRIs and SNRIs are considered to be first-line treatment agents because of their efficacy and favorable side effect profile.
Mental and behavioural disorder
Human diseases [BR:br08402]
 Other diseases
  Mental and behavioural disorders
   H01664  Panic disorder
Human diseases in ICD-11 classification [BR:br08403]
 06 Mental, behavioural or neurodevelopmental disorders
  Anxiety or fear-related disorders
   6B01  Panic disorder
    H01664  Panic disorder
Clonazepam [DR:D00280]
Alprazolam [DR:D00225]
Fluoxetine hydrochloride [DR:D00823]
Paroxetine hydrochloride hemihydrate [DR:D02260]
Paroxetine hydrochloride [DR:D05374]
Paroxetine mesylate [DR:D05375]
Sertraline hydrochloride [DR:D00825]
Venlafaxine hydrochloride [DR:D00821]
Other DBs
ICD-11: 6B01
ICD-10: F41.0
MeSH: D016584
OMIM: 167870
Roy-Byrne PP, Craske MG, Stein MB
Panic disorder.
Lancet 368:1023-32 (2006)
Li H, Wang J, Li C, Xiao Z
Repetitive transcranial magnetic stimulation (rTMS) for panic disorder in adults.
Cochrane Database Syst Rev CD009083 (2014)
Giampaolo P, Alessandra A, Raffaele B, Elisa M, Giuseppina D, Paolo C, Maria N, Daniela C
Is There Room for Second-Generation Antipsychotics in the Pharmacotherapy of Panic Disorder? A Systematic Review Based on PRISMA Guidelines.
Int J Mol Sci 17:551 (2016)

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