Dyslexia is defined by severe difficulties in reading acquisition, often accompanied by spelling difficulties and affects a large number of people (5-10%). It is caused by multiple genetic and environmental risk factors as well as their interplay. Several candidate genes have been identified in the past decade. However, effects of individual genetic variations on dyslexia-associated deficits are only moderate. At the brain level, dyslexia is associated with aberrant structure and function, particularly in left hemisphere reading-language networks.
