Neonatal intractable myoclonus (NEIMY) is a neurologic disorder characterized by severe infantile-onset myoclonus, hypotonia, optic nerve abnormalities, dysphagia, apnea, and early developmental arrest. Mutations of KIF5A, which encodes a neuron-specific kinesin-heavy chain involved in the intracellular transport of mitochondria and other cargoes, have been reported to be associated with this disease.
