Entry
Symbol
vorB
Name
2-oxoisovalerate ferredoxin oxidoreductase beta subunit [EC:
1.2.7.7 ]
Pathway
map00280 Valine, leucine and isoleucine degradation
map01210 2-Oxocarboxylic acid metabolism
Reaction
R07160 3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating;CoA-2-methylpropanoylating)
R08566 4-methyl-2-oxopentanoate:ferredoxin oxidoreductase (decarboxylating; CoA-3-methylbutanoylating)
R08567 (S)-3-methyl-2-oxopentanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylbutanoylating)
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
K00187 vorB; 2-oxoisovalerate ferredoxin oxidoreductase beta subunit
Enzymes [BR:ko01000 ]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.7 With an iron-sulfur protein as acceptor
1.2.7.7 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
K00187 vorB; 2-oxoisovalerate ferredoxin oxidoreductase beta subunit
Enzymes of 2-oxocarboxylic acid metabolism [br01601.html ]
2-Oxoacid oxidizing enzymes
K00187
BRITE hierarchy
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Genes
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Taxonomy UniProt
Reference
Authors
Heider J, Mai X, Adams MW
Title
Characterization of 2-ketoisovalerate ferredoxin oxidoreductase, a new and reversible coenzyme A-dependent enzyme involved in peptide fermentation by hyperthermophilic archaea.
Journal
Reference
Authors
Kletzin A, Adams MW
Title
Molecular and phylogenetic characterization of pyruvate and 2-ketoisovalerate ferredoxin oxidoreductases from Pyrococcus furiosus and pyruvate ferredoxin oxidoreductase from Thermotoga maritima.
Journal
Sequence
Reference
Authors
Tersteegen A, Linder D, Thauer RK, Hedderich R
Title
Structures and functions of four anabolic 2-oxoacid oxidoreductases in Methanobacterium thermoautotrophicum.
Journal
Sequence
LinkDB
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