KEGG   ORTHOLOGY: K01003
Entry
K01003                      KO                                     
Symbol
bcpA
Name
oxaloacetate decarboxylase [EC:4.1.1.112]
Pathway
map00620  Pyruvate metabolism
map01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K01003  bcpA; oxaloacetate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.112  oxaloacetate decarboxylase
     K01003  bcpA; oxaloacetate decarboxylase
Other DBs
RN: R00217
COG: COG2513
GO: 0008948
Genes
PAE: PA4872
PAEV: N297_5042
PAEI: N296_5042
PAU: PA14_64440(bcpA)
PAP: PSPA7_5594
PAG: PLES_52581
PAF: PAM18_4984
PNC: NCGM2_0654(bcpA)
PAEB: NCGM1900_5613(bcpA)
PDK: PADK2_25850
PSG: G655_25700
PRP: M062_25710
PAEP: PA1S_26460
PAER: PA1R_gp2794
PAEM: U769_26725
PAEL: T223_26920
PAES: SCV20265_5532
PAEU: BN889_05423
PAEG: AI22_07535
PAEC: M802_5040
PAEO: M801_4907
PMY: Pmen_0689
PMK: MDS_0774
PRE: PCA10_51200
PPSE: BN5_0574
PFUW: KF707C_51420
PALC: A0T30_06335
PCQ: PcP3B5_56180
PMUI: G4G71_06270
PPU: PP_1389
PPF: Pput_4334
PPG: PputGB1_4424
PPW: PputW619_1029 PputW619_5152
PPT: PPS_4264
PPB: PPUBIRD1_4171
PPI: YSA_02878
PPX: T1E_0246 T1E_1251
PPUH: B479_21440
PPUT: L483_26510
PPUN: PP4_09380
PPUD: DW66_4652
PFV: Psefu_4085
PMON: X969_20985
PMOT: X970_20620
PMOS: O165_000295
PPJ: RK21_00264
POR: APT59_20885
PMOL: CLJ08_07525
PST: PSPTO_1443
PSB: Psyr_1256
PSYR: N018_19415
PSP: PSPPH_1328(bcpA)
PSAV: PSA3335_10410
PAMG: BKM19_009200
PCI: PCH70_11520
PAVL: BKM03_08075
PVD: CFBP1590__4140
PCAB: JGS08_18535
PFL: PFL_2455
PPRC: PFLCHA0_c25150
PPRO: PPC_2494
PFE: PSF113_3877
PFO: Pfl01_2052 Pfl01_2772
PFS: PFLU_3105
PFC: PflA506_2644
PPZ: H045_06690
PFB: VO64_0355
PMAN: OU5_5864
PTV: AA957_00130
PCG: AXG94_25285
PVR: PverR02_15105
PAZO: AYR47_22365
POI: BOP93_12215
PRX: HRH33_13955
PFW: PF1751_v1c26670
PFF: PFLUOLIPICF723000
PFX: A7318_13420
PEN: PSEEN4356
PSA: PST_3733(bcpA)
PSZ: PSTAB_3695(bcpA)
PSR: PSTAA_3825(bcpA)
PSC: A458_02800
PSJ: PSJM300_07670 PSJM300_17035
PSH: Psest_0551
PSTU: UIB01_02505
PSTT: CH92_18585
PCHL: LLJ08_02675
PBM: CL52_17970
PLUL: FOB45_09370
PBA: PSEBR_a1851
PBC: CD58_20180
PPUU: PputUW4_03216
PDR: H681_21810
PSV: PVLB_04965
PSK: U771_12260
PKC: PKB_5190
PCH: EY04_11210
PCZ: PCL1606_37440
PCP: JM49_18735
PFZ: AV641_11725
PALK: PSAKL28_40210
PRH: LT40_20090
PSW: LK03_01240
PPV: NJ69_13060
PSES: PSCI_0548
PSEM: TO66_12015
PSEC: CCOS191_4259
PPSY: AOC04_08840
PSOS: POS17_2450
PKR: AYO71_13380
PFK: PFAS1_22385
PANR: A7J50_2850
PPSL: BJP27_15590
PSET: THL1_3205 THL1_5159
PSIL: PMA3_17455
PYM: AK972_2128
PSED: DM292_00575
PKE: DLD99_10910
PALL: UYA_03295
PUM: HGP31_12610
POJ: PtoMrB4_50070
PGG: FX982_04278
PPSH: G5J76_14920
PGY: AWU82_18565
PLAL: FXN65_25080
PSEJ: HNQ25_20885
PVK: EPZ47_10060
PEZ: HWQ56_12770
PBZ: GN234_07975
PKH: JLK41_03530
PTY: JWV26_14290
PMAO: PMYSY11_4000
PATA: JWU58_16845
PDW: BV82_0637
PZE: HU754_018685
PMOE: HV782_011605
PCAM: HNE05_01855
PSEP: C4K39_2367
PVW: HU752_022620
PTRT: HU722_0014560
PXA: KSS93_08595
PSAM: HU731_001710
PTZ: HU718_011810
PQI: KH389_07390
PXN: HU772_005160
PHV: HU739_002595 HU739_007225
PPRG: HU725_004745
PANH: HU763_019625
PASG: KSS96_15025
PFAK: KSS94_05355
PMUY: KSS95_08190
PMAM: KSS90_20675
PAZE: KSS91_10870
PALV: KSS97_10730
PORY: EJA05_05395
PWZ: J7655_03415
PTK: EXN22_08005
PTW: TUM18999_54370
PZA: HU749_011075
PIE: HU724_011255
PWY: HU734_006185
AVN: Avin_20130
AVL: AvCA_20130
AVD: AvCA6_20130
ACX: Achr_24790
HPEG: EAO82_13660
CSA: Csal_0251
EME: CEM_228
HAA: A5892_05580
KUS: B9G99_04730
KMA: B9H00_10430
KUY: FY550_15420
MMW: Mmwyl1_2926
MME: Marme_2883
MPC: Mar181_1138
MPRI: MP3633_1287
MARD: IBG28_07245
MFOI: JSY38_02020
MPRF: J8N69_12985
MARS: A8C75_13560
BXE: Bxe_B2147
BXB: DR64_4476
PDIO: PDMSB3_0965.1
BBRO: BAU06_03205
BOZ: DBV39_02745
BJA: bll5266(bll5266)
BJU: BJ6T_45150
BJP: RN69_21910
BRA: BRADO3250
BBT: BBta_4901
BRS: S23_30220
AOL: S58_31240
BRC: BCCGELA001_22110
BRAD: BF49_6364
BIC: LMTR13_17365
BRO: BRAD285_3147(OAD)
BRK: CWS35_21195
BOT: CIT37_28005
BRQ: CIT40_18365
BGQ: X265_22215
BGZ: XH91_15160
BSYM: CIT39_17655
BBET: F8237_29990
BARH: WN72_29400
BVZ: BRAD3257_3821
BEL: BE61_49010
BDG: LPJ38_27985
BSEP: HAP48_0043225
BQB: J4P68_0002615
RPA: RPA3174
RPB: RPB_2368
RPC: RPC_3351
RPD: RPD_3092
RPE: RPE_3438
RPT: Rpal_3584
RPX: Rpdx1_2253
RBK: E0H22_11460
TRB: HB776_05445
STAR: G3545_12755
RHZ: RHPLAN_70690
TSO: IZ6_12760
SECH: B18_11500
RMT: IAI58_06050
SHUM: STHU_15720
SVC: STVA_37320
STEL: STAQ_11820
PARH: I5S86_06185
 » show all
Reference
PMID:18081320
  Authors
Narayanan BC, Niu W, Han Y, Zou J, Mariano PS, Dunaway-Mariano D, Herzberg O
  Title
Structure and function of PA4872 from Pseudomonas aeruginosa, a novel class of oxaloacetate decarboxylase from the PEP mutase/isocitrate lyase superfamily.
  Journal
Biochemistry 47:167-82 (2008)
DOI:10.1021/bi701954p
  Sequence
[pae:PA4872]
LinkDB

KEGG   ENZYME: 4.1.1.112
Entry
EC 4.1.1.112                Enzyme                                 
Name
oxaloacetate decarboxylase;
oxaloacetate beta-decarboxylase;
oxalacetic acid decarboxylase;
oxalate beta-decarboxylase;
oxaloacetate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
oxaloacetate carboxy-lyase (pyruvate-forming)
Reaction(IUBMB)
oxaloacetate = pyruvate + CO2 [RN:R00217]
Reaction(KEGG)
R00217;
(other) R00995
Substrate
oxaloacetate [CPD:C00036]
Product
pyruvate [CPD:C00022];
CO2 [CPD:C00011]
Comment
Requires a divalent metal cation. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn2+, while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg2+. Unlike EC 7.2.4.2 [oxaloacetate decarboxylase (Na+ extruding)], there is no evidence of the enzyme's involvement in Na+ transport.
History
EC 4.1.1.112 created 1961 as EC 4.1.1.3, modified 1986, modified 2000, part transferred 2018 to EC 4.1.1.112
Pathway
ec00620  Pyruvate metabolism
ec01100  Metabolic pathways
Orthology
K01003  oxaloacetate decarboxylase
Genes
PAE: PA4872
PAEV: N297_5042
PAEI: N296_5042
PAU: PA14_64440(bcpA)
PAP: PSPA7_5594
PAG: PLES_52581
PAF: PAM18_4984
PNC: NCGM2_0654(bcpA)
PAEB: NCGM1900_5613(bcpA)
PDK: PADK2_25850
PSG: G655_25700
PRP: M062_25710
PAEP: PA1S_26460
PAER: PA1R_gp2794
PAEM: U769_26725
PAEL: T223_26920
PAES: SCV20265_5532
PAEU: BN889_05423
PAEG: AI22_07535
PAEC: M802_5040
PAEO: M801_4907
PMY: Pmen_0689
PMK: MDS_0774
PRE: PCA10_51200
PPSE: BN5_0574
PFUW: KF707C_51420
PALC: A0T30_06335
PCQ: PcP3B5_56180
PMUI: G4G71_06270
PPU: PP_1389
PPF: Pput_4334
PPG: PputGB1_4424
PPW: PputW619_1029 PputW619_5152
PPT: PPS_4264
PPB: PPUBIRD1_4171
PPI: YSA_02878
PPX: T1E_0246 T1E_1251
PPUH: B479_21440
PPUT: L483_26510
PPUN: PP4_09380
PPUD: DW66_4652
PFV: Psefu_4085
PMON: X969_20985
PMOT: X970_20620
PMOS: O165_000295
PPJ: RK21_00264
POR: APT59_20885
PMOL: CLJ08_07525
PST: PSPTO_1443
PSB: Psyr_1256
PSYR: N018_19415
PSP: PSPPH_1328(bcpA)
PSAV: PSA3335_10410
PAMG: BKM19_009200
PCI: PCH70_11520
PAVL: BKM03_08075
PVD: CFBP1590__4140
PCAB: JGS08_18535
PFL: PFL_2455
PPRC: PFLCHA0_c25150
PPRO: PPC_2494
PFE: PSF113_3877
PFO: Pfl01_2052 Pfl01_2772
PFS: PFLU_3105
PFC: PflA506_2644
PPZ: H045_06690
PFB: VO64_0355
PMAN: OU5_5864
PTV: AA957_00130
PCG: AXG94_25285
PVR: PverR02_15105
PAZO: AYR47_22365
POI: BOP93_12215
PRX: HRH33_13955
PFW: PF1751_v1c26670
PFF: PFLUOLIPICF723000
PFX: A7318_13420
PEN: PSEEN4356
PSA: PST_3733(bcpA)
PSZ: PSTAB_3695(bcpA)
PSR: PSTAA_3825(bcpA)
PSC: A458_02800
PSJ: PSJM300_07670 PSJM300_17035
PSH: Psest_0551
PSTU: UIB01_02505
PSTT: CH92_18585
PCHL: LLJ08_02675
PBM: CL52_17970
PLUL: FOB45_09370
PBA: PSEBR_a1851
PBC: CD58_20180
PPUU: PputUW4_03216
PDR: H681_21810
PSV: PVLB_04965
PSK: U771_12260
PKC: PKB_5190
PCH: EY04_11210
PCZ: PCL1606_37440
PCP: JM49_18735
PFZ: AV641_11725
PALK: PSAKL28_40210
PRH: LT40_20090
PSW: LK03_01240
PPV: NJ69_13060
PSES: PSCI_0548
PSEM: TO66_12015
PSEC: CCOS191_4259
PPSY: AOC04_08840
PSOS: POS17_2450
PKR: AYO71_13380
PFK: PFAS1_22385
PANR: A7J50_2850
PPSL: BJP27_15590
PSET: THL1_3205 THL1_5159
PSIL: PMA3_17455
PYM: AK972_2128
PSED: DM292_00575
PKE: DLD99_10910
PALL: UYA_03295
PUM: HGP31_12610
POJ: PtoMrB4_50070
PGG: FX982_04278
PPSH: G5J76_14920
PGY: AWU82_18565
PLAL: FXN65_25080
PSEJ: HNQ25_20885
PVK: EPZ47_10060
PEZ: HWQ56_12770
PBZ: GN234_07975
PKH: JLK41_03530
PTY: JWV26_14290
PMAO: PMYSY11_4000
PATA: JWU58_16845
PDW: BV82_0637
PZE: HU754_018685
PMOE: HV782_011605
PCAM: HNE05_01855
PSEP: C4K39_2367
PVW: HU752_022620
PTRT: HU722_0014560
PXA: KSS93_08595
PSAM: HU731_001710
PTZ: HU718_011810
PQI: KH389_07390
PXN: HU772_005160
PHV: HU739_002595 HU739_007225
PPRG: HU725_004745
PANH: HU763_019625
PASG: KSS96_15025
PFAK: KSS94_05355
PMUY: KSS95_08190
PMAM: KSS90_20675
PAZE: KSS91_10870
PALV: KSS97_10730
PORY: EJA05_05395
PWZ: J7655_03415
PTK: EXN22_08005
PTW: TUM18999_54370
PZA: HU749_011075
PIE: HU724_011255
PWY: HU734_006185
AVN: Avin_20130
AVL: AvCA_20130
AVD: AvCA6_20130
ACX: Achr_24790
HPEG: EAO82_13660
CSA: Csal_0251
EME: CEM_228
HAA: A5892_05580
KUS: B9G99_04730
KMA: B9H00_10430
KUY: FY550_15420
MMW: Mmwyl1_2926
MME: Marme_2883
MPC: Mar181_1138
MPRI: MP3633_1287
MARD: IBG28_07245
MFOI: JSY38_02020
MPRF: J8N69_12985
MARS: A8C75_13560
BXE: Bxe_B2147
BXB: DR64_4476
PDIO: PDMSB3_0965.1
BBRO: BAU06_03205
BOZ: DBV39_02745
BJA: bll5266(bll5266)
BJU: BJ6T_45150
BJP: RN69_21910
BRA: BRADO3250
BBT: BBta_4901
BRS: S23_30220
AOL: S58_31240
BRC: BCCGELA001_22110
BRAD: BF49_6364
BIC: LMTR13_17365
BRO: BRAD285_3147(OAD)
BRK: CWS35_21195
BOT: CIT37_28005
BRQ: CIT40_18365
BGQ: X265_22215
BGZ: XH91_15160
BSYM: CIT39_17655
BBET: F8237_29990
BARH: WN72_29400
BVZ: BRAD3257_3821
BEL: BE61_49010
BDG: LPJ38_27985
BSEP: HAP48_0043225
BQB: J4P68_0002615
RPA: RPA3174
RPB: RPB_2368
RPC: RPC_3351
RPD: RPD_3092
RPE: RPE_3438
RPT: Rpal_3584
RPX: Rpdx1_2253
RBK: E0H22_11460
TRB: HB776_05445
STAR: G3545_12755
RHZ: RHPLAN_70690
TSO: IZ6_12760
SECH: B18_11500
RMT: IAI58_06050
SHUM: STHU_15720
SVC: STVA_37320
STEL: STAQ_11820
PARH: I5S86_06185
 » show all
Reference
1  [PMID:5972993]
  Authors
Schmitt A, Bottke I, Siebert G.
  Title
[Properties of oxaloacetate decarboxylase from codfish muscles]
  Journal
Hoppe Seylers Z Physiol Chem 347:18-34 (1966)
Reference
2
  Authors
Herbert, D.
  Title
Oxalacetic carboxylase of Micrococcus lysodeikticus.
  Journal
Methods Enzymol 1:753-757 (1955)
Reference
3  [PMID:14205502]
  Authors
HORTON AA, KORNBERG HL.
  Title
OXALOACETATE 4-CARBOXY-LYASE FROM PSEUDOMONAS OVALIS CHESTER.
  Journal
Biochim Biophys Acta 89:381-3 (1964)
DOI:10.1016/0926-6569(64)90236-6
Reference
4  [PMID:15251467]
  Authors
Sender PD, Martin MG, Peiru S, Magni C
  Title
Characterization of an oxaloacetate decarboxylase that belongs to the malic enzyme family.
  Journal
FEBS Lett 570:217-22 (2004)
DOI:10.1016/j.febslet.2004.06.038
Reference
5  [PMID:18081320]
  Authors
Narayanan BC, Niu W, Han Y, Zou J, Mariano PS, Dunaway-Mariano D, Herzberg O
  Title
Structure and function of PA4872 from Pseudomonas aeruginosa, a novel class of oxaloacetate decarboxylase from the PEP mutase/isocitrate lyase superfamily.
  Journal
Biochemistry 47:167-82 (2008)
DOI:10.1021/bi701954p
  Sequence
[pae:PA4872]
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.112
IUBMB Enzyme Nomenclature: 4.1.1.112
ExPASy - ENZYME nomenclature database: 4.1.1.112
BRENDA, the Enzyme Database: 4.1.1.112
CAS: 9024-98-0
LinkDB

KEGG   REACTION: R00217
Entry
R00217                      Reaction                               
Name
oxaloacetate carboxy-lyase (pyruvate-forming)
Definition
Oxaloacetate <=> Pyruvate + CO2
Equation
C00036 <=> C00022 + C00011
Reaction class
RC00040  C00022_C00036
Enzyme
1.1.1.38        1.1.1.40        4.1.1.112
Pathway
rn00620  Pyruvate metabolism
rn01100  Metabolic pathways
Orthology
K01003  oxaloacetate decarboxylase [EC:4.1.1.112]
Other DBs
RHEA: 15644
LinkDB

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