ORTHOLOGY: K01131
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Entry
K01131 KO
Symbol
STS
Name
steryl-sulfatase [EC:
3.1.6.2
]
Pathway
map00140
Steroid hormone biosynthesis
map01100
Metabolic pathways
Reaction
R03404
3beta-hydroxyandrost-5-en-17-one 3-sulfate sulfohydrolase
R08941
cholesterol-sulfate sulfohydrolase
R08942
pregnenolone-sulfate sulfohydrolase
Disease
H00134
X-linked ichthyosis
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
K01131 STS; steryl-sulfatase
Enzymes [BR:
ko01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.6 Sulfuric-ester hydrolases
3.1.6.2 steryl-sulfatase
K01131 STS; steryl-sulfatase
BRITE hierarchy
Other DBs
GO:
0004773
Genes
HSA:
412
(STS)
PTR:
465478
(STS)
PPS:
100978949
(STS)
GGO:
101134717
(STS)
PON:
100438359
(STS)
PPYG:
129024327
(STS)
NLE:
100602490
(STS)
HMH:
116811507
(STS)
SSYN:
129476395
(STS)
MCC:
707799
(STS)
MCF:
102115360
(STS)
MTHB:
126946812
MNI:
105478088
(STS)
CSAB:
103231563
(STS)
CATY:
105574750
(STS)
PANU:
101007915
(STS)
TGE:
112615384
(STS)
MLEU:
105535170
(STS)
RRO:
104655513
(STS)
RBB:
108512225
(STS)
TFN:
117078216
(STS)
PTEH:
111536232
(STS)
CANG:
105522895
(STS)
CJC:
100414634
(STS)
SBQ:
101051637
(STS)
CIMI:
108291459
(STS)
ANAN:
105706914
(STS)
CSYR:
103261432
(STS)
MMUR:
105881028
(STS)
LCAT:
123628052
(STS)
PCOQ:
105820366
(STS)
OGA:
100950534
(STS)
MMU:
20905
(Sts)
MCAL:
110288170
RNO:
24800
(Sts)
MCOC:
116101779
(Sts)
ANU:
117695901
MUN:
110543032
CGE:
113838854
MAUA:
101836955
PLEU:
114689076
114689427
MORG:
121463704
(Sts)
MFOT:
126488878
AAMP:
119814254
(Sts)
NGI:
103751216
(Sts)
HGL:
101716720
(Sts)
CPOC:
100717716
106025956
CCAN:
109675117
(Sts)
DORD:
106000189
DSP:
122101927
122101928
122102695
PLOP:
125345315
(Sts)
NCAR:
124972128
MMMA:
107158749
(Sts)
OCU:
100344880
100356754
TUP:
102490574
(STS)
GVR:
103597154
(STS)
CFA:
491727
(STS)
CLUD:
112652465
(STS)
VVP:
112932375
(STS)
VLG:
121482271
(STS)
NPO:
129517538
(STS)
AML:
100483886
(STS)
UMR:
103666316
(STS)
UAH:
113240763
130543292
UAR:
123802745
(STS)
ELK:
111157126
LLV:
125091419
MPUF:
101684964
(STS)
MNP:
132007605
(STS)
MLK:
131822221
(STS)
NVS:
122897572
(STS)
ORO:
101384205
(STS)
EJU:
114218028
(STS)
ZCA:
113930607
(STS)
MLX:
118026690
(STS)
NSU:
110570193
(STS)
LWW:
102745530
FCA:
101082979
(STS)
PYU:
121020211
(STS)
PCOO:
112871636
(STS)
PBG:
122477937
(STS)
PVIV:
125157177
(STS)
LRUF:
124509333
PTG:
102957816
(STS)
PPAD:
109248261
(STS)
PUC:
125931461
AJU:
106969338
HHV:
120235971
(STS)
BTA:
509206
(STS)
BOM:
102264589
(STS)
BIU:
109555256
BBUB:
102399477
(STS)
BBIS:
104990343
CHX:
102187208
(STS)
OAS:
101118590
BTAX:
128070135
(STS)
ODA:
120881723
(STS)
CCAD:
122434703
(STS)
MBEZ:
129564114
(STS)
SSC:
448816
(STS)
CFR:
102508188
(STS)
CBAI:
105075975
(STS)
CDK:
105086567
(STS)
VPC:
102545057
(STS)
BACU:
103012756
(STS)
BMUS:
118888707
(STS)
LVE:
103084560
OOR:
101288711
(STS)
DLE:
111167220
(STS)
PCAD:
102976878
(STS)
PSIU:
116747748
(STS)
NASI:
112407106
(STS)
ECB:
100034102
(STS)
EPZ:
103542598
EAI:
106847868
(STS)
MYB:
102244992
(STS)
MYD:
102754250
(STS)
MMYO:
118657321
(STS)
MDT:
132223999
(STS)
PKL:
118721080
(STS)
EFUS:
103304599
(STS)
MNA:
107533017
(STS)
DRO:
112313384
(STS)
SHON:
118974306
(STS)
AJM:
119058289
(STS)
PHAS:
123829994
(STS)
MMF:
118636164
(STS)
PPAM:
129076887
(STS)
HAI:
109371890
(STS)
RFQ:
117021628
(STS)
PALE:
102882043
(STS)
PGIG:
120584068
(STS)
PVP:
105308972
(STS)
RAY:
107499525
(STS)
MJV:
108389387
(STS)
TOD:
119246360
(STS)
SARA:
101555515
(STS)
SETR:
126000580
(STS)
LAV:
100659001
(STS)
TMU:
101349984
ETF:
101658236
(STS)
DNM:
101424331
(STS)
MDO:
100032212
(STS)
GAS:
123242558
(STS)
SHR:
100928447
(STS)
AFZ:
127553661
PCW:
110221514
(STS)
TVP:
118837738
(STS)
OAA:
100084349
(STS)
GGA:
418654
(STS)
MGP:
100542513
(STS)
CJO:
107306057
(STS)
TPAI:
128092154
(STS)
LMUT:
125685466
(STS)
NMEL:
110405599
(STS)
APLA:
101798992
(STS)
ACYG:
106040526
(STS)
CATA:
118245687
(STS)
AFUL:
116486934
(STS)
TGU:
100226694
(STS)
LSR:
110476187
(STS)
SCAN:
103812668
(STS)
PMOA:
120504698
(STS)
OTC:
121342237
(STS)
PRUF:
121356187
(STS)
GFR:
102042856
(STS)
FAB:
101807918
(STS)
OMA:
130250205
(STS)
PHI:
102112221
(STS)
PMAJ:
107204502
(STS)
CCAE:
111922798
(STS)
CCW:
104686135
(STS)
CBRC:
103617572
(STS)
ETL:
114065003
(STS)
ZAB:
102073583
(STS)
ZLE:
135445754
(STS)
ACHL:
103801881
SVG:
106856803
MMEA:
130588896
(STS)
HRT:
120749228
(STS)
SATI:
136358038
(STS)
FPG:
101915634
(STS)
FCH:
102056250
(STS)
SHAB:
115603610
(STS)
ACUN:
113478121
(STS)
TALA:
116962051
(STS)
ACHC:
115334549
(STS)
HLE:
104839856
(STS)
AGEN:
126053066
GCL:
127025703
CSTI:
104559645
(STS)
LDI:
104345834
(STS)
DPUB:
104299247
(STS)
AVIT:
104281463
BRHI:
104492474
EGZ:
104127465
(STS)
NNI:
104014008
(STS)
PADL:
103924792
(STS)
AFOR:
103906010
(STS)
GSTE:
104260998
(STS)
CLV:
102091366
(STS)
PGUU:
104465575
(STS)
EHS:
104516970
(STS)
CUCA:
104063752
(STS)
TEO:
104383492
(STS)
OHA:
104337545
(STS)
ACAR:
104524946
CPEA:
104394981
(STS)
CVF:
104290360
(STS)
RTD:
128911239
(STS)
AAM:
106491417
(STS)
AROW:
112967786
(STS)
NPD:
112948174
(STS)
TGT:
104567037
(STS)
DNE:
112989575
(STS)
SCAM:
104149824
(STS)
ASN:
102368062
(STS)
AMJ:
102568637
(STS)
CPOO:
109306098
(STS)
GGN:
109302999
(STS)
PSS:
102454512
(STS)
CMY:
102945328
(STS)
CCAY:
125640965
(STS)
DCC:
119849802
(STS)
CPIC:
101931339
(STS)
TST:
117870274
(STS)
CABI:
116830519
(STS)
MRV:
120403749
(STS)
ACS:
100558860
(sts)
ASAO:
132771651
(STS)
PVT:
110075582
(STS)
SUND:
121925499
(STS)
PBI:
103055491
TSR:
106551577
(STS)
PGUT:
117673812
(STS)
APRI:
131199177
(STS)
PTEX:
113440748
(STS)
NSS:
113411689
(STS)
VKO:
123024611
(STS)
PMUA:
114596310
(STS)
PRAF:
128413231
(STS)
ZVI:
118085559
(STS)
HCG:
128351006
(STS)
GJA:
107120297
(STS)
STOW:
125431941
(STS)
EMC:
129325503
(STS)
XLA:
108709162
XTR:
100495327
(sts)
NPR:
108793972
RTEM:
120927460
BBUF:
120994885
(STS)
BGAR:
122932700
(STS)
DRE:
402795
(sts)
SRX:
107708663
107738478
SANH:
107691625
107699086
SGH:
107568784
107602762
CAUA:
113044420
(sts)
CGIB:
127948861
PTET:
122350209
(sts)
LROH:
127168055
(sts)
OMC:
131548909
(sts)
PPRM:
120468815
(sts)
RKG:
130087874
(sts)
MAMB:
125272373
(sts)
CIDE:
127510575
CERY:
137032673
(sts)
MASI:
127443545
127444923
TROS:
130553666
(sts)
TDW:
130436648
(sts)
MANU:
129426023
129436678
(sts)
IPU:
108259020
IFU:
128602035
(sts)
PHYP:
113537649
(sts)
SMEO:
124378280
(sts)
TFD:
113654085
(sts)
TVC:
132839431
(sts)
TRN:
134328615
(sts)
AMEX:
103021643
(sts)
CMAO:
118803053
(sts)
EEE:
113577503
(sts)
CHAR:
105904992
(sts)
TRU:
101066982
115248714
TFS:
130522990
(sts)
TNG:
GSTEN00027072G001
LCO:
104934755
(sts)
NCC:
104951992
(sts)
TBEN:
117498901
(sts)
PGEO:
117456579
(sts)
GACU:
117546614
(sts)
EMAC:
134860760
(sts)
SLUC:
116048610
(sts)
ECRA:
117939123
(sts)
ESP:
116674019
(sts)
PFLV:
114550907
(sts)
GAT:
120825392
(sts)
PPUG:
119218676
(sts)
AFB:
129111870
(sts)
CUD:
121506216
(sts)
ALAT:
119015463
(sts)
MZE:
101484545
106676298
ONL:
100696477
(sts)
OAU:
116322267
(sts)
OLA:
101168602
(sts)
OML:
112140215
(sts)
CSAI:
133425102
(sts)
PRET:
103477228
(sts)
PFOR:
103130065
(sts)
PLAI:
106964543
(sts)
PMEI:
106910080
(sts)
CTUL:
119776428
119778718
KMR:
108241831
(sts)
ALIM:
106511104
AOCE:
111580247
(sts)
MCEP:
125001248
(sts)
CSEM:
103389726
(sts)
POV:
109640051
(sts)
SSEN:
122765326
(sts)
HHIP:
117777846
(sts)
HSP:
118103625
(sts)
PPLT:
128431201
(sts)
LCF:
108902575
SDU:
111232859
(sts)
SLAL:
111670280
(sts)
XGL:
120797930
(sts)
BPEC:
110156608
(sts)
BSPL:
114851193
(sts)
SJO:
128354086
(sts)
SASA:
106575197
(sts)
STRU:
115179180
(sts)
OTW:
112253801
(sts)
OMY:
110527504
(sts)
OGO:
124008515
(sts)
ONE:
115133680
(sts)
OKI:
109890631
(sts)
OKE:
118370200
SALP:
111970941
(sts)
SNH:
120033393
(sts)
CCLU:
121586952
ELS:
105022503
SFM:
108929856
(sts)
PKI:
111846845
AANG:
118214200
(sts)
LOC:
102687095
(sts)
PSPA:
121327952
ARUT:
117405860
(sts)
PSEX:
120522858
(sts)
LCM:
102365522
(STS)
CMK:
103189013
(sts)
CPLA:
122550928
(sts)
HOC:
132816547
(sts)
LERI:
129714994
(sts)
PMRN:
116939360
LRJ:
133346984
BFO:
118404609
118404719
118404720
118404721
118404790
118404852
118409555
118410674
BBEL:
109464872
109467856
109468079
109473094
109476311
SCLV:
120328535
120337878
120337982
120338166
120338272
SPU:
591748
LPIC:
129261535
129264342
129264806
APLC:
110974921
110976705
110986317
110986341
ARUN:
117297577
117300929
117306817
AJC:
117115298
SKO:
100368835
100375077
100375222
100375374
100375449
100375528
100375822
BCOO:
119068978
HAME:
121864531
PPOI:
119092828
119092835
119113545
119114234
119114235
119114276
DSV:
119457648
RSAN:
119373975
RMP:
119167030
TUT:
107361477
DPTE:
113792690
DFR:
124499077
CSCU:
111623343
CVS:
136986907
PTEP:
107438283
ABRU:
129974881
UDV:
129217130
SDM:
118198367
LPOL:
106469933
HRO:
HELRODRAFT_97107
LGI:
LOTGIDRAFT_185807
PVUL:
126820339
126820340
130010508
PCAN:
112569296
112572657
GAE:
121370867
HRF:
124134869
HRJ:
124286141
CRG:
105341386
CANU:
128176015
128179034
CVN:
111129385
111129386
111131781
OED:
125650446
MYI:
110461470
110463928
110466093
PMAX:
117324155
117324491
117337486
MCAF:
127711041
MMER:
123545062
123545065
123545066
RPHI:
132750802
132750806
132757158
DPOL:
127872117
127873454
127874005
127878083
MAEA:
128209192
128234747
128236478
LJP:
135466297
135466310
135468765
135469057
LAK:
106173984
106176830
LLON:
135484470
NVE:
5505399
5507363
5507369
EPA:
110236969
110250465
ATEN:
116301967
ADF:
107341054
AMIL:
114960789
PDAM:
113672349
113677104
SPIS:
111330336
111331886
DGT:
114523510
114532458
114540707
XEN:
124441302
124447546
HMG:
100213116
HSY:
130613012
RES:
135683504
135683505
MBR:
MONBRDRAFT_32135
» show all
Taxonomy
UniProt
Reference
PMID:
2668275
Authors
Stein C, Hille A, Seidel J, Rijnbout S, Waheed A, Schmidt B, Geuze H, von Figura K
Title
Cloning and expression of human steroid-sulfatase. Membrane topology, glycosylation, and subcellular distribution in BHK-21 cells.
Journal
J Biol Chem 264:13865-72 (1989)
Sequence
[hsa:
412
]
LinkDB
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