ORTHOLOGY: K01742
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Entry
K01742 Tight KO
Symbol
THS
Name
thebaine synthase [EC:
4.2.99.24
]
Pathway
map00950
Isoquinoline alkaloid biosynthesis
map01100
Metabolic pathways
map01110
Biosynthesis of secondary metabolites
Module
M00944
Morphine biosynthesis, (S)-reticuline => morphine
Reaction
R04769
salutaridinol 7-O-acetate acetate-lyase (thebaine forming)
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00950 Isoquinoline alkaloid biosynthesis
K01742 THS; thebaine synthase
Enzymes [BR:
ko01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.99 Other carbon-oxygen lyases
4.2.99.24 thebaine synthase
K01742 THS; thebaine synthase
BRITE hierarchy
Genes
PSOM:
113322169
113340172
Taxonomy
UniProt
Reference
PMID:
29807982
Authors
Chen X, Hagel JM, Chang L, Tucker JE, Shiigi SA, Yelpaala Y, Chen HY, Estrada R, Colbeck J, Enquist-Newman M, Ibanez AB, Cottarel G, Vidanes GM, Facchini PJ
Title
A pathogenesis-related 10 protein catalyzes the final step in thebaine biosynthesis.
Journal
Nat Chem Biol 14:738-743 (2018)
DOI:
10.1038/s41589-018-0059-7
Sequence
[psom:
113322169
]
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