| Entry |
|
| Symbol |
hemH, FECH
|
| Name |
|
| Pathway |
| map01110 | Biosynthesis of secondary metabolites |
|
| Module |
| M00121 | Heme biosynthesis, plants and bacteria, glutamate => heme |
| M00868 | Heme biosynthesis, animals and fungi, glycine => heme |
| M00926 | Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme |
|
| Reaction |
| R00310 | protoheme ferro-lyase (protoporphyrin-forming) |
| R11329 | Fe-coproporphyrin-III ferro-lyase (coproporphyrin-III-forming) |
|
| Disease |
| H00201 | Erythropoietic porphyria |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
K01772 hemH, FECH; protoporphyrin/coproporphyrin ferrochelatase
Enzymes [BR:ko01000]
4. Lyases
4.98 ATP-independent chelatases
4.98.1 Forming coordination complexes
4.98.1.1 protoporphyrin ferrochelatase
K01772 hemH, FECH; protoporphyrin/coproporphyrin ferrochelatase
4.99 Other lyases
4.99.1 Sole sub-subclass for lyases that do not belong in the other subclasses
4.99.1.9 coproporphyrin ferrochelatase
K01772 hemH, FECH; protoporphyrin/coproporphyrin ferrochelatase
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| Other DBs |
|
| Genes |
» show all
|
| Reference |
|
| Authors |
Al-Karadaghi S, Hansson M, Nikonov S, Jonsson B, Hederstedt L |
| Title |
Crystal structure of ferrochelatase: the terminal enzyme in heme biosynthesis. |
| Journal |
|
| Sequence |
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| LinkDB |
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