KEGG ORTHOLOGY: K02578

KEGG

ORTHOLOGY: K02578

Entry

K02578                      KO

Symbol

NDST3

Name

heparan sulfate N-deacetylase/N-sulfotransferase NDST3 [EC:3.5.1.- 2.8.2.8]

Pathway

Glycosaminoglycan biosynthesis - heparan sulfate / heparin

Metabolic pathways

Module

Glycosaminoglycan biosynthesis, heparan sulfate backbone

Reaction

poly[(1->4)-beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl] amidohydrolase

3'-phosphoadenylyl-sulfate:heparosan-D-glucuronate N-sulfonotransferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
    K02578  NDST3; heparan sulfate N-deacetylase/N-sulfotransferase NDST3
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K02578  NDST3; heparan sulfate N-deacetylase/N-sulfotransferase NDST3
Enzymes [BR:ko01000]
2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.2  Sulfotransferases
    2.8.2.8  [heparan sulfate]-glucosamine N-sulfotransferase
     K02578  NDST3; heparan sulfate N-deacetylase/N-sulfotransferase NDST3
Glycosyltransferases [BR:ko01003]
Unclassified
  Sulfotransferases
   K02578  NDST3; heparan sulfate N-deacetylase/N-sulfotransferase NDST3

Other DBs

GO:	0102140 0015016

Genes

HSA:	9348(NDST3)

PTR:	471290(NDST3)

PPS:	100988204(NDST3)

GGO:	101143819(NDST3)

PON:	100443724(NDST3)

PPYG:

NLE:	100599264(NDST3)

HMH:

SSYN:

MCC:	704244(NDST3)

MCF:	102130633(NDST3)

MTHB:

MNI:	105486196(NDST3)

CSAB:

103236166(NDST3)

CATY:

105571481(NDST3)

PANU:

101015932(NDST3)

TGE:	112624565(NDST3)

MLEU:

105537921(NDST3)

RRO:	104663579(NDST3)

RBB:	108528882(NDST3)

TFN:	117085824(NDST3)

PTEH:

111547911(NDST3)

CANG:

105501414(NDST3)

CJC:

SBQ:	101039804(NDST3)

CIMI:

ANAN:

CSYR:

MMUR:

105883318(NDST3)

LCAT:

123627692(NDST3)

PCOQ:

105811231(NDST3)

OGA:	100951503(NDST3)

MMU:	83398(Ndst3)

MCAL:

MPAH:

RNO:	295430(Ndst3)

MCOC:

116093741(Ndst3)

ANU:	117707810(Ndst3)

ASYL:

MUN:	110556747(Ndst3)

CGE:

MAUA:

101840021(Ndst3)

PROB:

127223064(Ndst3)

PLEU:

114701386(Ndst3)

MORG:

MFOT:

AAMP:

119801084(Ndst3)

NGI:	103744298(Ndst3)

HGL:	101708542(Ndst3)

CPOC:

100719907(Ndst3)

CCAN:

DORD:

105991174(Ndst3)

DSP:	122123182(Ndst3)

PLOP:

NCAR:

MMMA:

ITI:

OCU:

OPI:

TUP:	102498357(NDST3)

GVR:	103607706(NDST3)

CFA:	487918(NDST3)

CLUD:

VVP:	112930966(NDST3)

VLG:	121492416(NDST3)

NPO:

AML:	100484094(NDST3)

UMR:	103661774(NDST3)

UAH:

UAR:	123793328(NDST3)

ELK:

LLV:

MPUF:

101686055(NDST3)

MNP:

MLK:

NVS:	122889205(NDST3)

ORO:	101368828(NDST3)

EJU:	114196676(NDST3)

ZCA:	113924105(NDST3)

MLX:	118027121(NDST3)

NSU:

LWW:	102741513(NDST3)

FCA:	101095009(NDST3)

PYU:

PCOO:

PBG:	122476798(NDST3)

PVIV:

LRUF:

LGF:	123593380(NDST3)

AJU:

PTG:	102964925(NDST3)

PPAD:

109248590(NDST3)

PUC:

PLEZ:

HHV:	120226337 120246339

BTA:	524136(NDST3)

BOM:

BIU:	109560231(NDST3)

BBUB:

102410649(NDST3)

BBIS:

104999674(NDST3)

CHX:	102171771(NDST3)

OAS:

BTAX:

CSUM:

ODA:	120861692(NDST3)

CCAD:

MREE:

OVR:

MBEZ:

SSC:	100525060(NDST3)

CFR:	102521813(NDST3)

CBAI:

105067137(NDST3)

CDK:	105093638(NDST3)

VPC:	102542828(NDST3)

BACU:

103003177(NDST3)

BMUS:

LVE:	103078588(NDST3)

OOR:

LALB:

DLE:	111186065(NDST3)

PCAD:

PSIU:

NASI:

ECB:	100064122(NDST3)

EPZ:

EAI:

MNA:	107527842(NDST3)

DRO:

PPAM:

HAI:	109373498(NDST3)

RFQ:

PALE:

PGIG:

PVP:

RAY:

MJV:

TOD:

SARA:

101552197(NDST3)

SFUM:

SETR:

LAV:

TMU:

ETF:	101643363(NDST3)

DNM:	101439444(NDST3)

MDO:	100011021(NDST3)

GAS:

PCW:

TVP:

PBRV:

OAA:

TACU:

GGA:	428769(NDST3)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

TGU:

LSR:

SCAN:

PMOA:

OTC:

PRUF:

ATRC:

GFR:	102042999(NDST3)

FAB:	101812030(NDST3)

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ACOE:

ETL:

ZAB:

ZLE:

ACHL:

103811573(NDST3)

SVG:

MMEA:

HRT:

SATI:

CCIC:

FPG:	101915418(NDST3)

FCH:

CCRI:

SHAB:

ACUN:

TALA:

ACHC:

HALD:

HLE:	104836803(NDST3)

AGEN:

HHAR:

GCL:

LDI:

MNB:

DPUB:

104310339(NDST3)

PPUS:

AVIT:

BRHI:

104491799(NDST3)

EGZ:

NNI:	104019134(NDST3)

PCRI:

PCAO:

PADL:

103926100(NDST3) 103926126

AFOR:

FGA:

GSTE:

CLV:

MUI:

PGUU:

PLET:

EHS:

CMAC:

104482331(NDST3)

CUCA:

TEO:

BREG:

OHA:

ACAR:

CPEA:

104389552(NDST3)

CVF:	104288998(NDST3)

RTD:

CRID:

AAM:

AROW:

NPD:

TGT:	104578392(NDST3)

DNE:

SCAM:

104144068(NDST3)

ASN:

AMJ:	102575391(NDST3)

CPOO:

GGN:

PSS:

CMY:

CCAY:

DCC:

CPIC:

TST:

CABI:

116814727 116830850

MRV:

ACS:	100568181(ndst3)

ASAO:

PVT:

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

APRI:

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:

HCG:

GJA:

STOW:

EMC:

XLA:	108706715 108710474

XTR:	100145653(ndst3)

NPR:

RTEM:

BBUF:

BGAR:

PWL:

MUO:

GSH:

LCM:	102347296(NDST3)

ARUN:

NVE:

HMG:

HSY:

Reference

Authors

Aikawa J, Esko JD

Title

Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family.

Journal

J Biol Chem 274:2690-5 (1999)
DOI:10.1074/jbc.274.5.2690

Sequence

[hsa:9348]

LinkDB

DBGET integrated database retrieval system