KEGG ORTHOLOGY: K03992

ORTHOLOGY: K03992

Entry

K03992                      KO

Symbol

MASP1

Name

mannan-binding lectin serine protease 1 [EC:3.4.21.-]

Pathway

map04610

Complement and coagulation cascades

map05150

Staphylococcus aureus infection

map05171

Coronavirus disease - COVID-19

Disease

H01887

3MC syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03992  MASP1; mannan-binding lectin serine protease 1
09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K03992  MASP1; mannan-binding lectin serine protease 1
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K03992  MASP1; mannan-binding lectin serine protease 1
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K03992  MASP1; mannan-binding lectin serine protease 1
Peptidases and inhibitors [BR:ko01002]
Serine peptidases
  Family S1: chymotrypsin family
   K03992  MASP1; mannan-binding lectin serine protease 1

Genes

HSA:	5648(MASP1)

PTR:	460925(MASP1)

PPS:	100970830(MASP1)

GGO:	101144543(MASP1)

PON:	100439814(MASP1)

PPYG:

129033709(MASP1)

NLE:	100601109(MASP1)

HMH:	116479952(MASP1)

SSYN:

134732982(MASP1)

MCC:	708206(MASP1)

MCF:	101866962(MASP1)

MTHB:

126946326

MNI:	105470889(MASP1)

CSAB:

103241880(MASP1)

CATY:

105575210(MASP1)

PANU:

101017684(MASP1)

TGE:	112619025(MASP1)

MLEU:

105527857(MASP1)

RRO:	104653539(MASP1)

RBB:	108530465(MASP1)

TFN:	117084356(MASP1)

PTEH:

111544269(MASP1)

CANG:

105525819(MASP1)

CJC:	100407253(MASP1)

SBQ:	101033147(MASP1)

CIMI:

108318507(MASP1)

ANAN:

105729900(MASP1)

CSYR:

103258708(MASP1)

MMUR:

105885053(MASP1)

LCAT:

123630375(MASP1)

ERUF:

138387961(MASP1)

PCOQ:

105807740(MASP1)

OGA:	100957750(MASP1)

MMU:	17174(Masp1)

MCAL:

110311194(Masp1)

MPAH:

110329505(Masp1)

RNO:	64023(Masp1)

MCOC:

116085754(Masp1)

ANU:	117717904(Masp1)

ASYL:

127666038(Masp1)

MUN:	110548132(Masp1)

CGE:	100774526(Masp1)

MAUA:

101823015(Masp1)

PROB:

127227005(Masp1)

PLEU:

114697103(Masp1)

PMAV:

102919197(Masp1)

MORG:

121465105(Masp1)

MFOT:

126512280

AAMP:

119824601(Masp1)

CNL:	130871168(Masp1)

NGI:	103750158(Masp1)

HGL:	101716867(Masp1)

CPOC:

100730575(Masp1)

CCAN:

109691384(Masp1)

DORD:

105999697(Masp1)

DSP:	122098289(Masp1)

DMER:

138832218(Masp1)

PLOP:

125351891(Masp1)

NCAR:

124993448

MMMA:

107154360(Masp1)

ITI:	101969600(Masp1)

OCU:

100009493

OPI:	101532013(MASP1)

OCZ:	121171179(MASP1)

TUP:	102495635(MASP1)

GVR:	103606680(MASP1)

CFA:	488121(MASP1)

CLUD:

112662696(MASP1)

VVP:	112926302(MASP1)

VLG:	121477498(MASP1)

NPO:	129498823(MASP1)

AML:	100480813(MASP1)

UMR:	103676043(MASP1)

UAH:	113253785(MASP1)

UAR:	123801287(MASP1)

ELK:

111147948

LLV:

125101939

MPUF:

101674101(MASP1)

MNP:	132011947(MASP1)

MLK:	131824743(MASP1)

NVS:	122908793(MASP1)

ORO:	101378116(MASP1)

EJU:	114207048(MASP1)

ZCA:	113917040(MASP1)

MLX:

118006928

MANO:

123863528(MASP1)

NSU:	110582385(MASP1)

LWW:	102742998(MASP1)

FCA:	101097166(MASP1)

PYU:	121034132(MASP1)

PCOO:

112849568(MASP1)

PBG:	122491622(MASP1)

PVIV:

125175034(MASP1)

LRUF:

124527013

LGF:	123611116(MASP1)

AJU:

106968007

PTG:	102955238(MASP1)

PPAD:

109275285(MASP1)

PUC:

125921819

PLEZ:

122230342(MASP1)

HHV:	120233096(MASP1)

CCRU:

144223731(MASP1)

BTA:	522347(MASP1)

BOM:	102281916(MASP1)

BIU:	109556918(MASP1)

BJV:	133245438(MASP1)

BKE:	129643729(MASP1)

BBIS:

104998636(MASP1)

CHX:	102171378(MASP1)

OAS:	101111065(MASP1)

OCAN:

138422746(MASP1)

BTAX:

128047794(MASP1)

CSUM:

138073551(MASP1)

ODA:	120872517(MASP1)

CCAD:

122444808(MASP1)

MREE:

136173056(MASP1)

OVR:	110122555(MASP1)

MBEZ:

129544622(MASP1)

SSC:	100152125(MASP1)

CFR:	102513366(MASP1)

CBAI:

105072340(MASP1)

CDK:	105085838(MASP1)

VPC:	102527442(MASP1)

BACU:

103011616(MASP1)

BMUS:

118894189(MASP1)

LVE:	103086594(MASP1)

OOR:	101285880(MASP1)

LALB:

132521071(MASP1)

GMF:	115855642(MASP1)

DDP:	132424838(MASP1)

DLE:	111172796(MASP1)

PCAD:

102991396(MASP1)

PSIU:

116753625(MASP1)

PPHC:

136122159(MASP1)

NASI:

112415119(MASP1)

ECB:	100068261(MASP1)

EPZ:	103560383(MASP1)

EAI:	106832546(MASP1)

MYB:	102243096(MASP1)

MYD:	102755101(MASP1)

MMYO:

118676900(MASP1)

MLF:	102427812(MASP1)

MDT:	132230214(MASP1)

MYUM:

139004004(MASP1)

PKL:	118723319(MASP1)

EFUS:

103295152(MASP1)

MNA:	107527305(MASP1)

DRO:	112305221(MASP1)

SHON:

118980417(MASP1)

AJM:	119039107(MASP1)

PDIC:

114490965(MASP1)

PHAS:

123826786(MASP1)

MMF:	118617162(MASP1)

PPAM:

129079869(MASP1)

HAI:	109371149(MASP1)

RFQ:	117032206(MASP1)

PALE:

102887394(MASP1)

PGIG:

120592859(MASP1)

PVP:	105306678(MASP1)

RAY:	107505896(MASP1)

MJV:	108401267(MASP1)

TOD:	119257384(MASP1)

SARA:

101540190(MASP1)

SFUM:

130030134(MASP1)

SETR:

126011932(MASP1)

LAV:	100664949(MASP1)

TMU:

101351430

ETF:	101648510(MASP1)

DNM:	101439403(MASP1)

MDO:	100012016(MASP1)

GAS:	123242800(MASP1)

SHR:	100928712(MASP1)

AFZ:

127556964

PCW:

110210181

TVP:	118846436(MASP1)

PBRV:

138157664(MASP1)

MLAO:

141490596(MASP1)

OAA:	100082252(MASP1)

TACU:

119930502(MASP1)

GGA:	407088(MASP1)

PCOC:

116235505(MASP1)

MGP:	100551064(MASP1)

CJO:	107318290(MASP1)

TPAI:

128082607(MASP1)

LMUT:

125697416(MASP1)

NMEL:

110398922(MASP1)

APLA:

101804768(MASP1)

AACU:

137861084(MASP1)

OJA:	118157700 118157707

ACYG:

106044834(MASP1)

CATA:

118247075(MASP1)

AFUL:

116492504(MASP1)

TGU:	100231782(MASP1)

LSR:	110473898(MASP1)

VMC:	128812395(MASP1)

VCHA:

128792885(MASP1)

AIB:	137479908(MASP1)

SCAN:

103815377(MASP1)

PMOA:

120504390(MASP1)

OTC:	121336542(MASP1)

PRUF:

121353768(MASP1)

ATRC:

139594995

MAEN:

136560658(MASP1)

GFR:	102035329(MASP1)

FAB:	101806498(MASP1)

OMA:	130256554(MASP1)

PHI:	102100134(MASP1)

PMAJ:

107209043(MASP1)

CCAE:

111933612(MASP1)

CCW:	104688121(MASP1)

CBRC:

103625156(MASP1)

ACOE:

138114800(MASP1)

ETL:	114057583(MASP1)

ZAB:

102067528

ZLE:	135451865(MASP1)

ACHL:

103812001(MASP1)

SVG:	106850391(MASP1)

MMEA:

130579654(MASP1)

HRT:	120757056(MASP1)

SATI:

136365464(MASP1)

CFAI:

136295089(MASP1)

CCIC:

134047577(MASP1)

FPG:	101918512(MASP1)

FCH:	102049370(MASP1)

FRS:	119156804(MASP1)

CCRI:

104157521

NNT:	104407852(MASP1)

SHAB:

115611918(MASP1)

POCC:

134168909(MASP1)

ACUN:

113483356(MASP1)

ANOC:

141963130(MASP1)

SURA:

141947251(MASP1)

TALA:

104368302

ACHC:

115347608(MASP1)

HLE:	104835231(MASP1)

AGEN:

126039832

HHAR:

128149496(MASP1)

BBUT:

142032685(MASP1)

GCL:

127020043

CSTI:

104556491(MASP1)

LDI:	104348825(MASP1)

MNB:	103776653(MASP1) 103780567

DPUB:

104302940(MASP1)

PPUS:

135187120(MASP1)

IIN:	128970602(MASP1)

AVIT:

104270298

BRHI:

104488963(MASP1)

EGZ:	104123371(MASP1)

NNI:	104015662(MASP1)

PCRI:

104035259(MASP1)

PCAO:

104052805

PARX:

142059834(MASP1)

PADL:

103916576(MASP1)

AFOR:

103901466(MASP1)

FGA:

104076480

CBOR:

142085344

GSTE:

104260888(MASP1)

CBOY:

140654274(MASP1)

MAME:

142412830 142413039

CLV:	102098561(MASP1)

CNIC:

135991745

MUI:

104545739

PGUU:

104460579(MASP1) 104461006

PLET:

104627977(MASP1)

EHS:	104507405(MASP1)

CMAC:

104479683(MASP1)

CUCA:

104063448(MASP1)

PCUR:

138724440(MASP1)

TEO:	104379676(MASP1)

BREG:

104637499(MASP1)

GAME:

129210251(MASP1)

OHA:	104326844(MASP1)

ACAR:

104529394(MASP1)

CPEA:

104391213(MASP1)

CVF:	104284965(MASP1)

RTD:	128910999(MASP1)

CRID:

134517782(MASP1)

LMIC:

141745251(MASP1)

NARQ:

141468304(MASP1)

AAM:	106498133(MASP1)

AROW:

112968506(MASP1)

NPD:	112952502(MASP1)

TGT:	104567275 104571092(MASP1)

DNE:	112979399(MASP1)

SCAM:

104148804(MASP1)

ASN:	102384513(MASP1)

AMJ:	102571302(MASP1)

CPOO:

109308542(MASP1)

GGN:	109288095(MASP1)

PSS:

102444258

CIZ:	142018414(MASP1)

CMY:	102939563(MASP1)

CCAY:

125643204(MASP1)

LKP:	140917056(MASP1)

NDS:	141993753(MASP1)

DCC:	119861602(MASP1)

CPIC:

101942804(MASP1)

TST:	117883406(MASP1)

EOB:	135883469(MASP1)

CABI:

116823020(MASP1)

MRV:	120372171(MASP1)

EMQ:	137161678(MASP1)

ACS:	100561598(masp1)

ASAO:

132770375(MASP1)

SUND:

121924980(MASP1)

PBI:	103054041(MASP1)

PMUR:

107298710(MASP1)

CTIG:

120296897(MASP1)

PGUT:

117657509

APRI:

131200709(MASP1)

NSS:	113428915(MASP1)

VKO:	123036801(MASP1)

PMUA:

114598179(MASP1)

PRAF:

128413332(MASP1)

ZVI:	118093632(MASP1)

HCG:	128350891(MASP1)

GJA:	107113844(MASP1)

STOW:

125438228(MASP1)

EMC:	129331885(MASP1)

XLA:	398413(masp1.S) 398414(ovch2l.L)

XTR:	100038300(masp1)

NPR:	108791178(MASP1)

RTEM:

120936866(MASP1)

ACAT:

141139874(MASP1)

PADS:

140328558(MASP1)

BBUF:

120997992(MASP1)

BGAR:

122934268(MASP1)

DTC:	141100725(MASP1)

PCOB:

134909527(MASP1)

PWL:	138265235(MASP1)

MUO:	115478624(MASP1)

GSH:	117366325(MASP1)

DRE:	100002060(masp1)

DAES:

130242361(masp1)

SRX:	107721148 107739768

SANH:

107683390 107704738

SGH:	107582221 107586740

CCAR:

109084544(masp1) 109104125

CAUA:

113058755 113078811 113114955

CGIB:

127972200 128028965

PTET:

122359497(masp1)

LROH:

127177170(masp1)

GRF:	141284996(masp1)

OMC:	131520763(masp1)

PPRM:

120478780(masp1)

RKG:	130077919(masp1)

MAMB:

125249372(masp1)

CIDE:

127496027

CERY:

137004801(masp1)

MASI:

127421764 127430241

TROS:

130565339(masp1)

TDW:	130429045(masp1)

MANU:

129438358(masp1)

PDAB:

135770831(masp1)

IPU:

108278363

IFU:	128621861(masp1)

PHYP:

113544654(masp1)

SMEO:

124394072(masp1)

TFD:	113637927(masp1)

TVC:	132846341(c1s.2) 132858078(masp1)

CGAR:

128532985(masp1)

NGRA:

132886394(c1s.2) 132900148(masp1)

TRN:	134334234(masp1)

AMEX:

103022902(masp1)

CMAO:

118798843(masp1)

EEE:	113588982(masp1) 113592077

CHAR:

105891531(masp1)

SPIL:

134099594(masp1)

ASAD:

121684217(masp1)

TRU:

101068213

TFS:

130535455

TNG:	GSTEN00021129G001 GSTEN00021132G001

LCO:	104934180(masp1)

TBEN:

117474434

CGOB:

115017421(masp1)

GACU:

117562557

EMAC:

134880146(masp1)

ELY:	117259113(masp1)

EFO:	125888591(masp1)

PLEP:

121944740(masp1)

SLUC:

116057060

GAT:	120816250(masp1)

PPUG:

119219088(masp1)

AFB:	129088929(masp1)

CLUM:

117745440

CANA:

137790350(masp1)

CVE:	137868516(masp1)

MSAM:

119883060(masp1)

SCHU:

122878608(masp1)

EARM:

139284868(masp1)

CUD:	121527182(masp1)

SPUL:

138596719(masp1)

LMIX:

132980969(masp1)

HTC:	141798178(masp1)

ALAT:

119012416(masp1)

ASTR:

137596318(masp1)

PKLU:

139200453(masp1)

MZE:	101472632(masp1)

ONL:

100694109

OAU:	116335343(masp1)

OML:	112149270(masp1)

CSAI:

133442053(masp1)

XMA:	102236429(masp1)

XCO:	114161716(masp1)

XHE:	116737665(masp1)

PRET:

103475256(masp1)

PFOR:

103152966(masp1)

PLAI:

106951496(masp1)

PMEI:

106914301(masp1)

GAF:	122832814(masp1)

PPRL:

129359237(masp1)

CTUL:

119791586(masp1)

GMU:	124884099(masp1)

NFU:

107379927

KMR:	108250973(masp1)

ALIM:

106534438(masp1)

NWH:	119411451(masp1)

LTU:	140313841(masp1)

AOCE:

111573564(masp1)

EJA:	138212672(masp1)

BFRE:

138627835(masp1)

MCEP:

125013715(masp1)

CSEM:

103378121(masp1)

POV:	109645354(masp1)

SSEN:

122760752

SSOE:

131462109(masp1)

HHIP:

117772444(masp1)

HSP:

118105987

PPLT:

128440511(masp1)

SMAU:

118297111(masp1)

LCF:

108902922

SDU:	111216830(masp1)

SLAL:

111646697(masp1)

XGL:	120791819(masp1)

HCQ:	109526211(masp1)

SBIA:

133505273(masp1)

PEE:

133405384

PTAO:

133482393(masp1)

BPEC:

110172161(masp1)

ENY:	140376552(masp1)

MALB:

109972737(masp1)

BSPL:

114868001(masp1)

SJO:	128360966(masp1)

SSCO:

133979976

TTY:	137186608(masp1)

GMH:	115528837(masp1)

SASA:

106612353(masp1)

STRU:

115205811(masp1)

OTW:	112247114(masp1)

OMY:	100301640(masp1)

OGO:	123994825(masp1)

ONE:	115106763(masp1)

OKI:	109864469(masp1)

OKE:	118366016(masp1)

OMM:	135514646(masp1)

OCLA:

139393150

SALP:

111960634(masp1)

SNH:	120028968(masp1)

SFON:

129832483(masp1)

CCLU:

121567273(masp1)

ELS:	105008657(masp1)

OEP:	134028998(masp1)

SFM:	108922148(masp1)

PKI:	111842724(masp1)

AANG:

118210203(masp1)

AROT:

135235669(masp1)

CCOG:

133108005(masp1)

LOC:	102695805(masp1)

PSPA:

121326814

ARUT:

117417277 117423734

PSEX:

120537096(masp1)

LCM:	102365424(MASP1)

CMK:	103190722(masp1)

RTP:	109920571(masp1)

CPLA:

122556089(masp1)

CPUN:

140478807(masp1)

HOC:	132821825(masp1)

SCAU:

119975878(masp1)

LERI:

129703175(masp1)

HAKA:

140725802(masp1)

PMRN:

116946805 116946910 116946911

LRJ:	133351126 133351128

BFO:

118430323

BBEL:

109468835 109479848

CIN:	100181065 100183415 100185892 100186241

SCLV:

120328427 120328428 120328726 120328886 120335519

CLEP:

143449738 143450305 143468417 143468663

APLC:

110986473 110989287 110989288

ARUN:

117302271 117302272 117302643

AAMU:

139950548 139950549 139950550 139950551 139950552 139950557 139950912

AFIL:

140156658

AJC:

117100518

PFLL:

139136178 139137091 139137749

RSAN:

PTEP:

ABRU:

HRJ:

NVE:	5501844 5505914 5516231

EPA:

110254010

ATEN:

116292343 116301129

ADF:	107334181 107334686 107354865

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

111332800 111332818 111338418

DGT:

114525919

XEN:	124444094 124452767

HMG:

100198529

HSY:

130628734

RES:	135688584 135696787

CCLM:

134182433

» show all

Reference

PMID:17182967

Authors

Moller-Kristensen M, Thiel S, Sjoholm A, Matsushita M, Jensenius JC

Title

Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway.

Journal

Int Immunol 19:141-9 (2007)
DOI:10.1093/intimm/dxl131

Sequence

[hsa:5648]

Reference

PMID:8240317

Authors

Takada F, Takayama Y, Hatsuse H, Kawakami M

Title

A new member of the C1s family of complement proteins found in a bactericidal factor, Ra-reactive factor, in human serum.

Journal

Biochem Biophys Res Commun 196:1003-9 (1993)
DOI:10.1006/bbrc.1993.2349

Sequence

[hsa:5648]

LinkDB

DBGET integrated database retrieval system