KEGG   ORTHOLOGY: K04010
Entry
K04010                      KO                                     

Symbol
C5AR1, CD88
Name
C5a anaphylatoxin chemotactic receptor 1
Pathway
map04080  Neuroactive ligand-receptor interaction
map04610  Complement and coagulation cascades
map04613  Neutrophil extracellular trap formation
map04936  Alcoholic liver disease
map05150  Staphylococcus aureus infection
map05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
   04613 Neutrophil extracellular trap formation
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
   04090 CD molecules
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Peptide
   Anaphylatoxin
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
CD molecules [BR:ko04090]
 Proteins
  K04010  CD88, C5R1; complement component 5 receptor 1 (C5a ligand)
Other DBs
GO: 0004878
Genes
HSA: 728(C5AR1)
PTR: 468931(C5AR1)
PPS: 100975182(C5AR1)
PON: 100455789(C5AR1)
NLE: 100589337(C5AR1)
MCC: 718056(C5AR1)
MCF: 102122506(C5AR1)
CSAB: 103234937(C5AR1)
CATY: 105595203(C5AR1)
PANU: 101024314(C5AR1)
RRO: 104673388(C5AR1)
RBB: 108540047(C5AR1)
TFN: 117091470(C5AR1)
PTEH: 111556087(C5AR1)
CJC: 100409718(C5AR1)
SBQ: 101034910(C5AR1)
MMUR: 105869586(C5AR1)
MMU: 12273(C5ar1)
MCAL: 110299315(C5ar1)
MPAH: 110337033(C5ar1)
RNO: 113959(C5ar1)
MCOC: 116100387(C5ar1)
MUN: 110561320(C5ar1)
CGE: 113837324
PLEU: 114681439(C5ar1)
NGI: 103724910(C5ar1)
HGL: 101713576(C5ar1)
OCU: 100352978(C5AR1)
OPI: 101519644(C5AR1)
TUP: 102500766(C5AR1)
CFA: 442974(C5AR1)
VVP: 112931331(C5AR1)
AML: 100470118(C5AR1)
UMR: 103657079(C5AR1)
UAH: 113243378(C5AR1)
ORO: 101367254(C5AR1)
ELK: 111160717
MPUF: 101692871(C5AR1)
EJU: 114197037(C5AR1)
MLX: 117998197(C5AR1)
FCA: 101098593(C5AR1)
PYU: 121018682(C5AR1)
PBG: 122493874(C5AR1)
PTG: 102962094(C5AR1)
PPAD: 109253169(C5AR1)
AJU: 106973630(C5AR1)
HHV: 120242817(C5AR1)
BTA: 493645(C5AR1)
BOM: 102284060(C5AR1)
BIU: 109572958(C5AR1)
BBUB: 102400801(C5AR1)
CHX: 102178657(C5AR1)
OAS: 101118296(C5AR1)
ODA: 120872229(C5AR1)
CCAD: 122420396(C5AR1)
SSC: 100048955(C5AR1)
CFR: 102505946(C5AR1)
CBAI: 105062561(C5AR1)
CDK: 105098917(C5AR1)
BACU: 103000958(C5AR1)
LVE: 103088737(C5AR1)
OOR: 101270207(C5AR1)
DLE: 111180688(C5AR1)
PCAD: 102976859(C5AR1)
ECB: 100065997(C5AR1)
EPZ: 103567448(C5AR1)
EAI: 106845159(C5AR1)
MYB: 102247978(C5AR1)
MYD: 102755212
MMYO: 118652814(C5AR1)
MNA: 107540051(C5AR1)
PKL: 118706769(C5AR1)
HAI: 109372198(C5AR1)
DRO: 112312961(C5AR1)
SHON: 118996167(C5AR1)
AJM: 119056650(C5AR1)
MMF: 118639243(C5AR1)
PALE: 102879583(C5AR1)
PGIG: 120617902(C5AR1)
RAY: 107516012(C5AR1)
MJV: 108398858(C5AR1)
TOD: 119250459(C5AR1)
LAV: 100660750(C5AR1)
TMU: 101348527
MDO: 100020568(C5AR1)
SHR: 100918726(C5AR1) 105750200
PCW: 110202379(C5AR1)
OAA: 100090459(C3AR1) 100092664(C5AR1)
GGA: 430484(C5AR1)
PCOC: 116241391
MGP: 104916038
CJO: 107307624
NMEL: 110391146
LSR: 110483676
PMOA: 120511904(C5AR1)
OTC: 121341209(C5AR1)
PRUF: 121364650(C5AR1)
PHI: 102111852
PMAJ: 107199300
FPG: 101921487(C5AR1)
FCH: 102047388
CLV: 102094460(C5AR1)
EGZ: 104126435
NNI: 104011814
PADL: 103922286(C5AR1)
AROW: 112977457
DNE: 112993081
ASN: 102372244
AMJ: 102564012(C5AR1)
CMY: 102933214 102933448(C5AR1)
CPIC: 101947905 101948363(C5AR1)
TST: 117888880(C5AR1)
CABI: 116819223(C5AR1) 116819224
ACS: 100562629(c5ar1)
PVT: 110075705(C5AR1)
PBI: 103051246
PMUR: 107285685(C5AR1)
TSR: 106541066(C5AR1)
PGUT: 117677619(C5AR1)
PMUA: 114603411(C5AR1)
ZVI: 118086643(C5AR1)
GJA: 107106907(C5AR1)
XLA: 108698596(c5ar1.L) 108700674(c5ar1.S)
XTR: 100379958(c5ar1)
DRE: 100000959(c5ar1) 794255(c3ar1)
IPU: 108264848(c5ar1) 108277390
TRU: 105417034
LCO: 109141185
NCC: 104944122
CGOB: 115018190
ELY: 117259678
PLEP: 121943329
SLUC: 116043850
ECRA: 117942056
PFLV: 114553310
GAT: 120822456
PPUG: 119217494
MSAM: 119883099
CUD: 121524238
OLA: 101169056
OML: 112141280
XMA: 102232131
XCO: 114133225
XHE: 116707918
PRET: 103474750
CVG: 107101236
CTUL: 119784020
NFU: 107380692
KMR: 108238127
ALIM: 106522175
AOCE: 111569386
CSEM: 103377630
POV: 109634470
LCF: 108879410
SDU: 111222557
SLAL: 111651336
XGL: 120792055
BPEC: 110162019
RTP: 109924785
 » show all
Reference
PMID:2007135
  Authors
Boulay F, Mery L, Tardif M, Brouchon L, Vignais P
  Title
Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells.
  Journal
Biochemistry 30:2993-9 (1991)
DOI:10.1021/bi00226a002
  Sequence
[hsa:728]
Reference
  Authors
Cheng L, Bu H, Portillo JA, Li Y, Subauste CS, Huang SS, Kern TS, Lin F
  Title
Modulation of retinal Muller cells by complement receptor C5aR.
  Journal
Invest Ophthalmol Vis Sci 54:8191-8 (2013)
DOI:10.1167/iovs.13-12428
  Sequence
[hsa:728]
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