KEGG ORTHOLOGY: K04265

ORTHOLOGY: K04265

Entry

K04265                      KO

Symbol

ADORA1

Name

adenosine receptor A1

Pathway

map04022

cGMP-PKG signaling pathway

map04024

cAMP signaling pathway

map04071

Sphingolipid signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04923

Regulation of lipolysis in adipocytes

map04924

Renin secretion

map05032

Morphine addiction

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    K04265  ADORA1; adenosine receptor A1
   04024 cAMP signaling pathway
    K04265  ADORA1; adenosine receptor A1
   04022 cGMP-PKG signaling pathway
    K04265  ADORA1; adenosine receptor A1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04265  ADORA1; adenosine receptor A1
09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    K04265  ADORA1; adenosine receptor A1
   04924 Renin secretion
    K04265  ADORA1; adenosine receptor A1
09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    K04265  ADORA1; adenosine receptor A1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04265  ADORA1; adenosine receptor A1
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Base and nucleoside
   Adenosine
    K04265  ADORA1; adenosine receptor A1

Other DBs

GO:

0001609

TC:	9.A.14.3.4

Genes

HSA:	134(ADORA1)

PTR:	457638(ADORA1)

PPS:	100993503(ADORA1)

GGO:	101140567(ADORA1)

PON:	100171559(ADORA1)

NLE:	100599470(ADORA1)

HMH:	116457382(ADORA1)

MCC:	703638(ADORA1)

MTHB:

126939189

MNI:	105484761(ADORA1)

CSAB:

103230289(ADORA1)

CATY:

105575750(ADORA1)

PANU:

101000554(ADORA1)

TGE:	112611223(ADORA1)

MLEU:

105547086(ADORA1)

RRO:	104674493(ADORA1)

RBB:	108514998(ADORA1)

TFN:	117076241(ADORA1)

PTEH:

111522788(ADORA1)

CANG:

105504357(ADORA1)

CJC:	100394821(ADORA1)

SBQ:	101029943(ADORA1)

CIMI:

108302005(ADORA1)

CSYR:

103262817(ADORA1)

MMUR:

105868113(ADORA1)

LCAT:

123626974(ADORA1)

PCOQ:

105819633(ADORA1)

OGA:	100957132(ADORA1)

MMU:	11539(Adora1)

MCAL:

110290054(Adora1)

MPAH:

110321257(Adora1)

RNO:	29290(Adora1)

MCOC:

116099441(Adora1)

ANU:	117716248(Adora1)

MUN:	110546745(Adora1)

CGE:	100751346(Adora1)

MAUA:

101823380(Adora1)

PROB:

127236322(Adora1)

PLEU:

114698103(Adora1)

MORG:

121445962(Adora1)

MFOT:

126505002

AAMP:

119828152(Adora1)

NGI:	103731858(Adora1)

HGL:	101704638(Adora1)

CPOC:

100135472(Adora1)

CCAN:

109686310(Adora1)

DORD:

105986458(Adora1)

DSP:	122109495(Adora1)

PLOP:

125359648(Adora1)

NCAR:

124962441

MMMA:

107140690(Adora1)

OCU:	100328615(ADORA1)

OPI:	101532500(ADORA1)

TUP:	102474600(ADORA1)

GVR:	103594417(ADORA1)

CFA:	403961(ADORA1)

CLUD:

112667032(ADORA1)

VVP:	112934507(ADORA1)

VLG:	121493554(ADORA1)

NPO:	129505743(ADORA1)

AML:	100482278(ADORA1)

UMR:	103657790(ADORA1)

UAH:	113242522(ADORA1)

UAR:	123785722(ADORA1)

ELK:

111151074

LLV:

125085965

MPUF:

101682988(ADORA1)

MNP:	132025624(ADORA1)

MLK:	131815141(ADORA1)

NVS:	122918809(ADORA1)

ORO:	101374348(ADORA1)

EJU:	114221998(ADORA1)

ZCA:	113932308(ADORA1)

MLX:	118014180(ADORA1)

NSU:	110577304(ADORA1)

LWW:	102730849 102740567(ADORA1)

FCA:	101100536(ADORA1)

PYU:	121021623(ADORA1)

PCOO:

112857717

PBG:	122476195(ADORA1)

PVIV:

125155629(ADORA1)

LRUF:

124510399

PTG:	102954668(ADORA1)

PPAD:

109256643(ADORA1)

PUC:

125925425

AJU:

106971862

HHV:	120228840(ADORA1)

BTA:	282133(ADORA1)

BOM:	102268681(ADORA1)

BBUB:

102399744(ADORA1)

BBIS:

104998778(ADORA1)

CHX:	102181801(ADORA1)

OAS:	101109816(ADORA1)

BTAX:

128061784(ADORA1)

ODA:	120879988(ADORA1)

CCAD:

122451977(ADORA1)

MBEZ:

129551794(ADORA1)

SSC:	606743(ADORA1)

CFR:	102510349(ADORA1)

CBAI:

105062241(ADORA1)

CDK:	105092098(ADORA1)

VPC:	102538982(ADORA1)

BACU:

103010703(ADORA1)

BMUS:

118892263(ADORA1)

LVE:	103087697(ADORA1)

OOR:	101288190(ADORA1)

DLE:	111184588(ADORA1)

PCAD:

102995842

PSIU:

116741695(ADORA1)

NASI:

112403586(ADORA1)

ECB:	100052496(ADORA1)

EPZ:	103555122(ADORA1)

EAI:	106840068(ADORA1)

MYB:	102242144(ADORA1)

MYD:	102757676(ADORA1)

MMYO:

118653087(ADORA1)

MLF:	102441590(ADORA1) 111824436

PKL:	118710529(ADORA1)

EFUS:

103302922(ADORA1)

MNA:	107536004(ADORA1)

DRO:	112318875(ADORA1)

SHON:

119003903(ADORA1)

AJM:	119060807(ADORA1)

PDIC:

114512319(ADORA1)

PHAS:

123832995(ADORA1)

MMF:	118640633(ADORA1)

PPAM:

129072918(ADORA1)

HAI:	109380484(ADORA1)

RFQ:	117018518(ADORA1)

PALE:

102881697(ADORA1)

PGIG:

120619299(ADORA1)

PVP:	105296923(ADORA1)

RAY:	107503000(ADORA1)

MJV:	108401669(ADORA1)

TOD:	119233997(ADORA1)

SARA:

101537830(ADORA1)

SETR:

126004205(ADORA1)

LAV:	100676506(ADORA1)

TMU:

101358747

ETF:	101639707(ADORA1)

DNM:	101432615(ADORA1)

GAS:	123245518(ADORA1)

SHR:	100921347(ADORA1)

AFZ:

127562702

PCW:	110219653(ADORA1)

OAA:	107547061(ADORA1)

GGA:	374212(ADORA1)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

125684310(ADORA1)

NMEL:

110388309

APLA:

101799728(ADORA1)

ACYG:

106045857(ADORA1)

CATA:

118255367(ADORA1)

AFUL:

116498752(ADORA1)

TGU:	100222054(ADORA3)

LSR:

110469168

SCAN:

103822373

PMOA:

120497297

OTC:	121345590(ADORA1)

PRUF:

121365396

GFR:	102042862(ADORA1)

FAB:	101813655(ADORA1)

OMA:	130263767(ADORA1)

PHI:

102104539

PMAJ:

107215040

CCAE:

111939632

CCW:	104692466(ADORA1)

CBRC:

103616480(ADORA1)

ETL:	114071490(ADORA1)

ZAB:

102064597

ACHL:

103805611(ADORA1)

SVG:

106862788

MMEA:

130578338(ADORA1)

HRT:	120762770(ADORA1)

FPG:	101915753(ADORA1)

FCH:	102050136(ADORA1)

CLV:

102084846

EGZ:	104121992(ADORA1)

NNI:	104011090(ADORA1)

PCRI:

104036066(ADORA1)

PLET:

104621436(ADORA1)

EHS:	104514468(ADORA1)

PCAO:

104042760(ADORA1)

ACUN:

113488994

TALA:

104365072(ADORA1)

PADL:

103926257(ADORA1)

AFOR:

103901051(ADORA1)

ACHC:

115335186(ADORA1)

HALD:

104319041(ADORA1)

HLE:	104842307(ADORA1)

AGEN:

126052113

GCL:

127026357

CCRI:

104163304(ADORA1)

CMAC:

104487330

MUI:	104536004(ADORA1)

BREG:

104631344(ADORA1)

FGA:	104078921(ADORA1)

GSTE:

104254241(ADORA1)

LDI:	104346356(ADORA1)

MNB:	103768906(ADORA1)

OHA:	104337058(ADORA1)

NNT:	104404310(ADORA1)

SHAB:

115602304(ADORA1)

DPUB:

104296241(ADORA1)

PGUU:

104464017(ADORA1)

ACAR:

104527979(ADORA1)

CPEA:

104385639(ADORA1)

AVIT:

104278348(ADORA1)

CVF:	104283158(ADORA1)

RTD:	128900393(ADORA1)

CUCA:

104058999(ADORA1)

TEO:	104376639(ADORA1)

BRHI:

104493414(ADORA1)

AAM:	106485635(ADORA1)

AROW:

112965083(ADORA1)

NPD:	112959218(ADORA1)

TGT:	104569350(ADORA1)

DNE:	112983843(ADORA1)

SCAM:

104139249(ADORA1)

ASN:	102368890(ADORA1)

AMJ:	102561012(ADORA1)

CPOO:

109317591(ADORA1)

PSS:	102461617(ADORA1)

CMY:	102932493(ADORA1)

CCAY:

125625106(ADORA1)

DCC:	119846374(ADORA1)

CPIC:

101939990(ADORA1)

TST:	117875953(ADORA1)

CABI:

116837316(ADORA1)

MRV:	120404537(ADORA1)

ACS:

100567853

ASAO:

132773299(ADORA1)

PVT:

110073404

SUND:

121928781(ADORA1)

PBI:	103066676(ADORA3)

PMUR:

107294288

CTIG:

120297018(ADORA1)

TSR:

106548844

PGUT:

117663746(ADORA1)

APRI:

131194752(ADORA1)

PTEX:

113434261(ADORA1)

NSS:

113420772

VKO:	123031983(ADORA1)

PMUA:

114599442

PRAF:

128416254(ADORA1)

ZVI:

118089500

HCG:	128322318(ADORA1)

GJA:

107114828

STOW:

125433876

EMC:

129330764

XLA:	108709406(adora1.S) 378623(adora1.L)

XTR:	100127730(adora1)

NPR:	108796147(ADORA1)

RTEM:

120926999(ADORA1)

BBUF:

120994947

BGAR:

122930291

MUO:	115457449 115481670(ADORA1)

GSH:	117347870(ADORA1)

DRE:	100007535 100150997(adora1b) 108179103 562364(si:ch211-233f11.5) 571410

SRX:	107711940 107723864 107724513 107724526 107731293 107744374 107744409 107746529 107753800

SANH:

107655990 107666000 107666046 107666146 107668012 107674552 107680252 107696416 107696453 107696943

SGH:	107550463 107559159 107587646 107591868 107595403 107595437 107595453 107602815

CCAR:

109048780 109053466 109060195 109072096 109073747 109073748 109091695 109091728 109101732 109106703

CAUA:

113041023 113050144 113050145 113055056 113071176 113071177 113071178 113077666 113078332 113078337 113088843 113088857 113093922 113104330 113107626 113110963 113116727

CGIB:

127959953 127960097 127960285 127960287 127963021 127967872 127974851 128011196 128015176 128016010 128018664 128022486

PTET:

122329285 122346525 122346526(adora4a) 122346603 122350213(adora1b) 122354453

LROH:

127154783 127159783 127166909(adora4a) 127166911 127166912 127170256(adora1b) 127173383

OMC:	131532461 131542810 131542811 131542812(adora4a) 131546273(adora1b) 131549682

PPRM:

120464207 120469180(adora1b) 120493367 120493368 120493369

RKG:	130086587 130094627(adora1b) 130104016 130104017 130104018 130104135

MAMB:

125244184 125260121 125273309(adora4a) 125273322 125273323 125273324 125277701 125280392(adora1b)

CIDE:

127504913 127514474 127514475 127514476 127518012 127522719

MASI:

127414457 127419269 127423812 127426350 127428239 127446386 127448970

TROS:

130557146 130557147 130568658(adora1b) 130571096

TDW:	130409545 130410390 130424533 130424534(adora4a) 130425025 130440307(adora1b)

MANU:

129414855(adora1b) 129427951 129450099 129450100 129450634 129450635 129450852 129450870 129450880 129450881 129450985

IPU:	108255230 108265083(adora1b)

IFU:	128607894(adora1b) 128625344

PHYP:

113539504 113547473

SMEO:

124400493(adora1b) 124401996

TFD:	113641582 113655955(adora1b)

TVC:	132838432 132853319(adora1b)

AMEX:

103021694 103022025 103022582 103028963 103040267 103047448 103047745 111193393 111193665 111193686 111193687 111194551

EEE:	113568774 113571578 113571607 113571655 113585538

CHAR:

105889847 105898142 105907348 105907358 105907367 105907377 105907387 105907398 105907410 105907420 105912002

TRU:	101066824 101071030 101075254 101080153

TFS:	130524103 130530503(adora1b)

TNG:	GSTEN00013961G001 GSTEN00028166G001 GSTEN00033896G001 GSTEN00033897G001

LCO:	104918381 104926662 104935386 109140254 109140525

NCC:	104941391 104941431 104941554 104943008 104964417(adora1)

TBEN:

117486446 117489787 117489788 117489874 117494037(adora1b) 117494077

CGOB:

115008362 115008412 115008413 115010776 115010989

PGEO:

117446129 117446938 117447162 117447224 117449829(adora1b) 117450085

GACU:

117539484 117539580 117539581 117539597 117542073(adora1b) 117542103 117547540

EMAC:

134868179 134870660(adora1b) 134882534 134883257 134883464

ELY:	117256385 117256656 117257406 117257850(adora1b) 117257914

EFO:	125880418 125880466 125880538 125890411 125890420 125892331(adora1b) 125892397 125893490

PLEP:

121947068(adora1b) 121947394 121949137 121954275 121959369 121959385 121961540

SLUC:

116037522 116040998(adora1b) 116051612 116051615 116058552 116067218 116067219 116067221 116067314

ECRA:

117934980 117943325 117943547 117943548 117948098(adora1b)

ESP:	116688120 116688232 116688347 116692627 116707017

PFLV:

114554042 114554043 114554369 114557249 114558349 114559202

GAT:	120829476(adora1b) 120835291 120835356 120835357 120835657

PPUG:

119194111 119194183 119199475 119222793(adora1b) 119229753 119229754

AFB:	129099305 129100249(adora1b) 129105644 129106070 129106212 129106356 129106367 129114875

CLUM:

117730365 117730998 117731061 117731183 117733697(adora1b) 117733823

PSWI:

130200028 130200069(adora1b) 130208020 130208221 130208942

MSAM:

119886116 119886461 119886462 119886782 119896857 119904935(adora1b) 119906079

SCHU:

122868149 122882424 122883521(adora1b) 122884537 122884549 122884830

CUD:	121506955 121506956 121507030 121507284 121507550 121517920(adora1b) 121518089

ALAT:

119006161 119020553 119020554 119021947 119022415 119023569(adora1b)

MZE:	101465939 101466221 101483264 101484151 106674504

ONL:	100691101 100697719 100698410 100698466 100703648 100705788

OAU:	116309765(adora1b) 116317772 116317791 116326552 116330833 120440129

OLA:	101166301 101169688 101170509

OML:	112140782 112145352 112159329(adora1b)

CSAI:

133448807 133449302 133449303 133449304 133456466 133457243(adora1b)

XMA:	102230114 102230812 102230832 102231468 102231988 102236858 111608089

XCO:	114134903 114134950 114134951 114135725 114145253 114152202

XHE:	116709968 116709977 116709988 116710041 116710042 116710499 116721999 116726472

PRET:

103464675 103464702 103464703 103464836 103464901 103467282

PFOR:

103129675 103134595 103134596 103134708 103144349 103149627

PLAI:

106946654 106954206 106954207 106955213 106956282 106960250 106964313

PMEI:

106917388 106920997 106920999 106925448 106928278 106932892 106932894

GAF:	122828098 122833486 122833487 122834189 122837231(adora1b)

PPRL:

129358206 129372349 129372529(adora1b) 129372809 129372825 129372830

CVG:	107087471 107097102 107101078 107101204 107101311 107101312 107104125

CTUL:

119778972 119779017 119782157(adora1b) 119784315 119788628 119791749 119797861

GMU:	124856648 124857000 124857163 124857401 124862705 124865618 124872372(adora1b)

NFU:	107384929 107385566 107385935 107390814 107390952

KMR:	108231553 108231554 108231580 108236725(adora1b) 108246852

ALIM:

106513325 106517598 106518285 106525561

NWH:	119409676 119412458 119412625 119412808 119417285(adora1b)

AOCE:

111573852 111575919 111579627 111583423 111587437

MCEP:

124997681(adora1b) 125006101 125006523 125006929 125007283

CSEM:

103384601 103386155 103386545

POV:	109629057 109630902 109633188 109635100 109635377 109635451

SSEN:

122767659 122767716 122777112(adora1b) 122777299

HHIP:

117761355 117761463 117762079 117764020 117764834(adora1b)

HSP:	118104831 118104832 118105472 118110485(adora1b) 118111267

SMAU:

118307120 118309392 118309393 118309645 118316337(adora1b) 118316704

LCF:	108873564 108873569 108873604 108876537(adora1b) 108877936 108889424

SDU:	111218942 111219123 111219439 111219487 111221901 111233618

SLAL:

111648661 111660653 111662354 111662355 111667704 111669006 111670744

XGL:	120782935 120783024 120783127 120783261 120784003 120803304(adora1b)

HCQ:	109508136 109508429 109510346 109522680

SSCV:

125977536 125977635 125977637 125977647 125988849

SBIA:

133494897(adora1b) 133507469 133507541 133507574

PEE:	133408628 133409309 133409310 133411846(adora1b)

PTAO:

133479833 133483223 133483501 133483680 133485115(adora1b)

BPEC:

110159114 110164975 110171205 110174381 110174713

MALB:

109954023 109955910 109970633 109971202

BSPL:

114843573 114855419 114856111 114856349 114858471(adora1b) 114858878

SJO:	128355315 128355734 128355778 128355905 128357585(adora1b) 128357889 128367010

SASA:

106566069 106566075 106566076 106566082 106566400 106572854 106582617 106582690 106582721 106605680

STRU:

115151012 115151013 115151049 115168665 115207368 115207415 115207417 115207418

OTW:	112215245(adora1b) 112221791 112222402 112235405 112254164 112254199 112255443 112262653 112262659 112262666 112263095

OMY:	110491174 110493273 110494711 110494753 110495198 110527718 110527750 110527752 110532795(adora1b) 110537974

OGO:	123998034 124002436 124004349 124004354 124021078 124031600 124031601 124032361(adora1b)

ONE:	115101610 115116126 115120941 115123462 115135871 115143785 115143786 115143787 115145345

OKI:	109866024 109866120 109874228 109878374 109886965 109890141 109890841 109891502 109899614

OKE:	118360457 118374412 118380145 118389441 118389617 118389618 118399925 118399958 118399959

SALP:

111969702 111970626 111970632 111970636 111970648 112069855 112073031 112079991

SNH:	120020322 120024188 120024300 120059551(adora1b) 120061713 120065572 120065581 120065582

CCLU:

121537349 121546808 121574762 121575777 121575828 121578361 121578486 121578712

ELS:	105008158 105008641 105023759 105027121

SFM:	108918249 108931201 108938250(adora1) 108939165

PKI:	111837006 111837482 111837499 111855247 111856177

AANG:

118207226(adora1b) 118207588 118210962 118210963 118210964 118210965 118211742

LOC:	102689714 102691072(adora1) 102694730 107076769

PSPA:

121299663 121299737 121299913 121300190 121300288 121300293 121304781

ARUT:

117397011 117424804 117426491 117428822 117431118 117433483 117965982 117966030 117966051 117970437 117972105

PSEX:

120526241 120526244 120526267(adora1b)

LCM:	102365445 102365876

CMK:	103179076 103179090

RTP:

109915435

CPLA:

122544250 122563242 122563244

HOC:	132828118 132828415

LERI:

ACER:

ALAB:

ADR:

AFLR:

BPYO:

BPAS:

FVI:

OLG:

VPS:

VCRB:

NPT:

NFB:

NLO:

NVG:

HVI:

PTRU:

PPOI:

HRF:

CVN:

CANU:

OED:	125681749 130051629

MYI:

110460397

RPHI:

132729928

EPA:	110231452 110254651

ATEN:

116292388 116293038 116293464 116298397 116298414 116298416 116301085 116301094 116303337 116303518 116305726 116306855 116307100 116307121 116307482 116307629 116307817 116308620

ADF:	107329886 107335812 107336969 107352314

AMIL:

114967002 114977856

PDAM:

113668646 113669553 113670714 113672872 113673472 113684127 113685548

SPIS:

111331397 111338327 111341316 111341317 111343166

XEN:	124440023 124442728 124443497 124443998 124445629 124452274

HSY:	130614204 130646072 130649566

» show all

Reference

PMID:8300646

Authors

Ren H, Stiles GL

Title

Characterization of the human A1 adenosine receptor gene. Evidence for alternative splicing.

Journal

J Biol Chem 269:3104-10 (1994)

Sequence

[hsa:134]

LinkDB

DBGET integrated database retrieval system