Homo sapiens (human): 134 Help Entry 134               CDS       T01001                                  Symbol ADORA1, RDC7 Name (RefSeq) adenosine A1 receptor   KO K04265   adenosine receptor A1 Organism hsa  Homo sapiens (human) Pathway hsa04022   cGMP-PKG signaling pathway hsa04024   cAMP signaling pathway hsa04071   Sphingolipid signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04923   Regulation of lipolysis in adipocytes hsa04924   Renin secretion hsa05032   Morphine addiction Drug target Adenosine (DG00243):  D00045<JP/US> D02300<JP> D02769 D08646 D08647 Aminophylline (DG01062):  D00227 D05429<JP> D11630<US> Apaxifylline:  D02964 Bamifylline (DG01064):  D03051 D07491 Caffeine (DG00974):  D00528<JP> D01453<JP> D07603<US> Choline theophyllinate:  D02017 Diprophylline:  D00691<JP> Enprofylline:  D04006 Naxifylline:  D05125 Proxyphylline:  D01771 Rolofylline:  D08989 Selodenoson:  D05818 Tecadenoson:  D06019 Theophylline (DG01061):  D00371<JP/US> D01712 D06103 D06104 Tonapofylline:  D09684 Trabodenoson:  D10493 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04071 Sphingolipid signaling pathway     134 (ADORA1)    04024 cAMP signaling pathway     134 (ADORA1)    04022 cGMP-PKG signaling pathway     134 (ADORA1)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     134 (ADORA1)    04082 Neuroactive ligand signaling     134 (ADORA1)  09150 Organismal Systems   09152 Endocrine system    04923 Regulation of lipolysis in adipocytes     134 (ADORA1)    04924 Renin secretion     134 (ADORA1)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     134 (ADORA1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     134 (ADORA1) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Base and nucleoside    Adenosine     134 (ADORA1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx Motif Other DBs NCBI-GeneID:  134 NCBI-ProteinID:  NP_000665 OMIM:  102775 HGNC:  262 Ensembl:  ENSG00000163485 UniProt:  P30542 Structure PDBPDBj LinkDB All DBs Position 1:203127726..203167405 Genome browser AA seq 326 aa AA seqDB search MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL KIWNDHFRCQPAPPIDEDLPEERPDD NT seq 981 nt NT seq  +upstreamnt  +downstreamnt atgccgccctccatctcagctttccaggccgcctacatcggcatcgaggtgctcatcgcc ctggtctctgtgcccgggaacgtgctggtgatctgggcggtgaaggtgaaccaggcgctg cgggatgccaccttctgcttcatcgtgtcgctggcggtggctgatgtggccgtgggtgcc ctggtcatccccctcgccatcctcatcaacattgggccacagacctacttccacacctgc ctcatggttgcctgtccggtcctcatcctcacccagagctccatcctggccctgctggca attgctgtggaccgctacctccgggtcaagatccctctccggtacaagatggtggtgacc ccccggagggcggcggtggccatagccggctgctggatcctctccttcgtggtgggactg acccctatgtttggctggaacaatctgagtgcggtggagcgggcctgggcagccaacggc agcatgggggagcccgtgatcaagtgcgagttcgagaaggtcatcagcatggagtacatg gtctacttcaacttctttgtgtgggtgctgcccccgcttctcctcatggtcctcatctac ctggaggtcttctacctaatccgcaagcagctcaacaagaaggtgtcggcctcctccggc gacccgcagaagtactatgggaaggagctgaagatcgccaagtcgctggccctcatcctc ttcctctttgccctcagctggctgcctttgcacatcctcaactgcatcaccctcttctgc ccgtcctgccacaagcccagcatccttacctacattgccatcttcctcacgcacggcaac tcggccatgaaccccattgtctatgccttccgcatccagaagttccgcgtcaccttcctt aagatttggaatgaccatttccgctgccagcctgcacctcccattgacgaggatctccca gaagagaggcctgatgactag

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